Agent Name |
n-Propyl alcohol |
Alternative Name |
n-Propanol |
CAS Number |
71-23-8 |
Formula |
C3-H8-O |
Major Category |
Solvents |
Synonyms |
1-Hydroxypropane; 1-Propyl alcohol; Albacol; Alcohol, propyl; Alcool propilico [Italian]; Alcool propylique [French]; Ethyl carbinol; Ethylcarbinol; Optal; Osmosol Extra; Propanol; Propanol-1; Propanole [German]; Propanolen [Dutch]; Propanoli [Italian]; Propyl alcohol (natural); Propyl alcohol, normal; Propylic alcohol; Propylowy alkohol [Polish]; n-Propan-1-ol; n-Propanol; n-Propyl alcohol; n-Propyl alkohol [German]; [ChemIDplus] UN1274 |
Category |
Alcohols and Polyols |
Description |
Colorless liquid with a mild, alcohol-like odor; [NIOSH] |
Sources/Uses |
Used as a solvent, antiseptic, and chemical intermediate; [ACGIH] Used as a solvent in inks, pesticides, and lacquers; [HSDB] |
Comments |
A mucous membrane irritant similar to isopropyl alcohol, n-propyl alcohol produces narcosis in animals inhaling high concentrations. It causes severe liver injury in chronic feeding studies of laboratory animals. [ACGIH] Irritating to the eyes; Inhalation of high concentrations can cause CNS depression; [ICSC] |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
100 ppm |
STEL (ACGIH) |
400 ppm |
PEL (OSHA) |
200 ppm |
IDLH (NIOSH) |
800 ppm |
Excerpts from Documentation for IDLHs |
Human data: Mild irritation of the eyes, nose, and throat have been reported at 400 ppm [Nelson et al. 1943]. It has been reported that 5,700 mg/kg is the lethal oral dose [Durwald and Degen 1956]. [Note: An oral dose of 5,700 mg/kg is equivalent to a 70�kg worker being exposed to about 94,000 ppm for 30 minutes, assuming a breathing rate of 50 liters per minute and 100% absorption.] |
Vapor Pressure |
21 mm Hg |
Odor Threshold Low |
0.03 ppm |
Odor Threshold High |
41 ppm |
Lethal Concentration |
LCLo (rats) = 4,000 ppm/4H |
Explanatory Notes |
Detection odor threshold from AIHA (mean = 5.3 ppm); Flash point = 23 deg C; |
Half Life |
No reports found; [TDR, p. 1052] |
Flammability (NFPA) |
3: may ignite at ambient temperature |
Adverse Effects |
Neurotoxin |
CNS Solvent Syndrome |
Hepatotoxin |
Hepatotoxin, Secondary |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: N-PROPANOL
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