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Selected Publications

Clinical Pathology Group

  1. Auerbach SS, Mahler J, Travlos GS, Irwin RD. A comparative 90 day toxicity study of allyl acetate, allyl alcohol and acrolein. Toxicology 253(1-3):79-88, 2008.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18817840) Exit NIEHS
  2. Auman JT, Boorman GA, Wilson RE, Travlos GS, Paules RS. Heat map visualization of high-density clinical chemistry data. Physiol. Genomics 31(2):352-356, 2007.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17652165?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum) Exit NIEHS
  3. Baird DD, Travlos GS. Obesity and insulin-like growth factor-1 in African Americans and Whites. Cancer Epidemiol. Biomarkers Prev. 16(7):1526, 2007.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17627022?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum) Exit NIEHS
  4. Dunnick, JK, Thayer, KA, Travlos, GS. Inclusion of Biomarkers for Detecting Perturbations in the Heart and Lung and Lipid/Carbohydrate Metabolism in National Toxicology Program Studies. Toxicol. Sci. 100(1):29-35, 2007.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17490986) Exit NIEHS
  5. Travlos, G. S.: Histopathology of bone marrow. Toxicol. Pathol., 34:566-598, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17067944) Exit NIEHS
  6. Travlos, G. S.: Normal structure, function, and histology of the bone marrow. Toxicol. Pathol., 34:548-565, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17067943) Exit NIEHS
  7. Peddada SD, Haseman JK, Tan, X, Travlos G. Tests for simple tree order restriction with application to dose-response studies. Appl. Statist. 55:493-506, 2006.
  8. Anderson LM, Riffle L, Wilson, R, Travlos GS, Lubomirski MS, Alvord WG. Preconceptional fasting of fathers alters serum glucose in offspring of mice. Nutrition. 22:327-331, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16500559) Exit NIEHS
  9. Chan P, Mahler J, Travlos GS, Nyska A, Wenk M. Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice. Arch Toxicol. 23:1-12, 2005.
  10. Rhodes MC, Hebert CD, Herbert RA, Morinello EJ, Roycroft JH, Travlos GS, Abdo KM. Absence of toxic effects in F344/N rats and B6C3F1 mice following subchronic administration of chromium picolinate monohydrate. Food Chem Toxicol. 43 (1):21-29, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15582192) Exit NIEHS
  11. Boorman GA, Irwin RD, Vallant MK, Gerken DK, Lobenhofer EK, Hejmancik MR, Hurban P, Brys AM, Travlos GS, Parker JS, Portier CJ. Variation in the hepatic gene expression in individual male Fisher rats. Toxicol Pathol. 33 (1):102-110, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15805061) Exit NIEHS
  12. Heinloth, AN, Irwin, RD, Boorman, GA, Nettesheim, P, Fannin, RD, Sieber, SO, Snell, ML, Tucker, CJ, Li, L, Travlos, GS, Vansant, G, Blackshear, PE, Tennant, RW, Cunningham, ML, Paules RS. Gene expression profiling of rat livers reveals indicators of potential adverse effects. Toxicol Sci. 80(1):193-202, 2004.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15084756) Exit NIEHS
  13. Cisneros, F. J., Wilson, R., Travlos, G. S., Anderson, L. M. and Branch, S. Susceptibility to postnatal growth retardation induced by 5-aza-2'-deoxycytidine In Utero: Gender specificity and correlation with reduced insulin-like growth factor. FASEB J. 17: A779-A779 Part 2 Suppl. S Mar., 2003.
  14. Cisneros, F. J., Wilson, R., Travlos, G. S., Anderson, L. M. and Branch, S. Susceptibility to Postnatal Growth Retardation Induced by 5-Aza-2'-deoxycytidine In Utero: Gender Specificity and Correlation with Reduced Insulin-like Growth Factor 1. Life Sci. 72:2887-2894, 2003.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12697271) Exit NIEHS
  15. Ress, N.B., Maronpot, R.A., Hailey, J.R., Bucher, J.R., Travlos, G.S., Haseman, J.K., Hejtmancik, M.R. Toxicology and carcinogenesis studies of microencapsulated citral in rats and mice. Toxicol. Sci.: 71; 198-206, 2003.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12563105) Exit NIEHS
  16. Nyska, A., Moomaw, C. R., Foley, J. F., Maronpot, R. R., Malarky, D. E., Cummings, C. A.,Peddada, S., Moyer, C. F., Allen, D. G., Travlos, G. S., and Chan, P. C.: The Hepatic Endothelial Carcinogen Riddelliine Induces Endothelial Apoptosis, Mitosis, S Phase, and p53 and Hepatic Vascular Endothelial Growth Factor Expression after Short-term Exposure. Tox. Appl. Pharm. 184: 153-164, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12460743) Exit NIEHS
  17. London, S. J., Yuan, J. M., Travlos, G. S., Gao, Y. T., Wilson, R. E., Ross, R. K. and Yu, M. C. Insulin-like growth factor I, IGF-binding protein 3, and lung cancer risk in a prospective study of men in China. J. Natl. Cancer I. 94 (10): 749-754. 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12011225) Exit NIEHS
  18. Abdo, K. M., Cunningham, M. L., Snell, M. L., Herbert, R. A., Travlos, G. S., Eldridge, S. R. and Bucher, J. R.: 14-Week Toxicity and Cell Proliferation of Methyleugenol Administered by Gavage to F344 Rats and B6C3F1 Mice. Food Chem. Toxicol., 39: 303-316, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11295478) Exit NIEHS
  19. Hooth, M. J., DeAngelo, A. B., George, M. H., Gaillard, E. T., Travlos, G. S., Boorman, G. A. andWolf, D. C.: Subchronic Sodium Chlorate Exposure in Drinking Water Results in a Concentration-Dependent Increase in Rat Thyroid Follicular Cell Hyperplasia. Toxicol. Pathol., 29: 250-259, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11421493) Exit NIEHS
  20. Chhabra, R.S., Herbert, R. A., Bucher, J. R., Travlos, G. S., Johnson, J. D. and Hejtmancik, M. R.: Toxicology and Carcinogenesis Studies of p, p'-Dichlorodiphenyl Sulfone in Rats and Mice. Toxicol. Sci. 60: 28-37, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11222870) Exit NIEHS
  21. Travlos, G. S., Wilson, R. E., Murrell, J. A., Chignell, C. F. and Boorman, G. A.: The Effect of Short Intermittent Light Exposures on the Melatonin Circadian Rhythm and NMU-Induced Breast Cancer in Female F344/N Rats. Toxicol. Pathol., 29: 126-136, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11215676) Exit NIEHS
  22. Davis, B. J., Travlos, G. S. and McShane, T.Reproductive Endrocrinology and Toxicological Pathology over the Life Span of the Female Rodent. Toxicol. Pathol., 29: 77-83, 2001.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11215687) Exit NIEHS
  23. Nyska, A., Maronpot, R. R., Long, P. H., Roycroft, J. H., Hailey, J. R., Travlos, G. S., and Ghanayem, B. I.: Disseminated Thrombosis and Bone Marrow Infarction in Female Rats Following Inhalation Exposure to 2-Butoxyethanol. Toxicol. Pathol., 27: 287-294, 1999.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10356705) Exit NIEHS
  24. van Birgelen, A., Herbert, C. D., Wenk, M. L., Grimes, L. K., Chapin, R. E., Travlos, G. S., Mahler, J., and Bucher, J. R.: Toxicity of 3, 3’, 4, 4’-Tetrachloroazoxybenzene in Rats and Mice. Toxicol. Appl. Pharmacol., 156: 206-221, 1999.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10222313) Exit NIEHS
  25. van Birgelen, A., Herbert, C. D., Wenk, M. L., Grimes, L. K., Chapin, R. E., Mahler, J., Travlos, G. S., and Bucher, J. R.: Toxicity of 3, 3’, 4, 4’-Tetrachloroazobenzene in Rats and Mice. Toxicol. Appl. Pharmacol., 156: 147-159, 1998.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10198280) Exit NIEHS
  26. Janke, G. D., Marr, M., Myers, C., Wilson, R., Travlos, G., and Price, C.: Maternal and Developmental Toxicity Evaluation of Melatonin Administered Orally to Pregnant Sprague Dawley Rats - A Screening Study. Toxicol. Sci. 50: 271-279, 1999.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10478864) Exit NIEHS
  27. Qu, W., Rippe, R. A., Ma, J., Scarborough, P., Biagini, C., Fiedorek, F. T., Travlos, G. S., Parker, C., and Zeldin, D. C.: Nutritional Status Modulates Rat Liver P450 Arachidonic Acid Metabolism. Mol. Pharmacol. 54: 504-513, 1998.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9730909) Exit NIEHS
  28. Baldwin, W. S., Travlos, G. S., Risinger, J. I., and Barrett, J. C.: Melatonin Does Not Inhibit Estradiol-Stimulated Proliferation in MCF-7 and BG-1 Cells. Carcinogenesis 19: 1895-1900, 1998.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9854999) Exit NIEHS
  29. Dunn, S. E., Kari, F. W., French, J., Leininger, J. R., Travlos, G., Wilson, R., and Barrett, J. C.: Dietary Restricion Reduces Insulin-like Growth Factor I Levels, Which Modulates Apoptosis, Cell Proliferation, and Tumor Prgression in p53-deficient mice. Cancer Res. 57: 4667-4672, 1997.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9354418) Exit NIEHS
  30. Davis, B. J., Almekinder, J. L., Johnson, T. R., Flagler, N., Travlos, G. S., Wilson, R., and Maronpot, R. R.: Ovarian Luteal Cell Toxicity of Ethylene Glycol Monomethyl Ether and Methoxy Acetic Acid in Vivo and in Vitro. Tox. Appl. Pharm. 142: 328-337, 1997.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9070356) Exit NIEHS
  31. Boorman, G. A., Gauger, J. R., Johnson, T. R., Tomlinson, M. J., Travlos, G. S. and McCormick, D. L.: Eight Week Toxicity Study of 60 Hz Magnetic Fields in F344 rats and B6C3F1 Mice.Fundam. Appl. Toxicol. 35: 55-63, 1997.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9024673) Exit NIEHS
  32. Travlos, G. S., Mahler, J., Ragan, H. A., Chou, B. J., and Bucher, J. R.: 13-Week Inhalation Toxicity of 2-and 4-Chloronitrobenzene in F344/N Rats and B6C3F1 Mice. Fundam. Appl. Toxicol., 30: 75-92, 1996.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8812232) Exit NIEHS
  33. Travlos, G. S., Morris, R. W., Elwell, M. R., Duke, A., Kennedy, S., and Thompson, M. B.: Frequency and Relationships of Clinical Chemistry and Liver and Kidney Histopathology Findings in 13-Week Toxicity Studies in Rats. Toxicol. 107: 17-29, 1996.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8597028) Exit NIEHS
  34. Bucher, J. R., Morgan, D. L., Adkins, B., Travlos, G. S., Davis, B. J., Morris, R., and Elwell, M. R.: Early Changes in Sex Hormones are not Evident in Mice Exposed to the Uterine Carcinogens Chloroethane or Bromoethane. Tox. Appl. Pharm. 130: 169-173, 1995.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7839365) Exit NIEHS
  35. Chan, P. C., Mahler, J., Bucher, J. R., Travlos, G. S., and Reid, J. B.: Toxicity and Carcinogenicity of Riddelliine Following 13 Weeks of Treatment to Rats and Mice. Toxicon. 32 (8): 891-908, 1994.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7985194) Exit NIEHS
  36. Hebert, C. D., Elwell, M. R., Travlos, G. S., Fitz, C. J., and Bucher, J. R.: Subchronic Toxicity of Cupric Sulfate Administered in Drinking Water and Feed to Rats and Mice. Fundam. Appl. Toxicol. 21:461-475, 1993.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8253299) Exit NIEHS
  37. Hebert, C. D., Elwell, M. R., Travlos, G. S., Zieger, E. French, J. E., and Bucher, J. R.: Inhalation Toxicity of 1,6-Hexanediamine Dihydrochloride in F344/N Rats and B6C3F1 Mice. Fundam. Appl. Toxicol. 20: 348-359, 1993.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8504909) Exit NIEHS
  38. Morgan DL, Price HC, O’Connor RW, Seely JC, Ward SM, Wilson RE, Cunningham MC. Upper respiratory tract toxicity of inhaled methylvinyl ketone in F344 rats and B6C3F1 mice. Toxicol Sci. 2000 Nov;58(1):182-94.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11053555) Exit NIEHS
  39. Trempus CS, Mahler JF, Ward SM, Wilson R, Streicker M, Moser G, Tice R, Goldsworthy TL, Tennant RW. Toxicity associated with topical exposure of v-Ha-ras Tg.AC mice Toxicity associated with topical exposure.
  40. Ghanayem BI, Ward SM, Chanas B, Nyska A. Comparison of the acute hematotoxicity of 2-butoxyethanol in male and female F344 rats. Hum Exp Toxicol. 2000 Mar;19(3):185-92.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10889517) Exit NIEHS
  41. Klein J-LD, Roberts JD, George MD, Kurtzberg J, Breton P, Chermann J-C, Olden K. Swainsonine protects both murine and human haematopoietic systems from chemotherapeutic toxicity. Brit J Cancer. 1999;80(1/2):87-95. Acknowledgement to Sandra Ward.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10389983) Exit NIEHS
  42. Effect of Gender on the hematotoxicity of 2-butoxyethanol (BE) in F344 rats. Chanas B, Ward S, Healy R, Nyska A, Ghanayem B. Abstract presented at SOT Annual Meeting 1999.
  43. Inhalation toxicity studies of methylvinyl ketone in rats and mice. Morgan DL, Price HC, O’Connor RW, Mahler JF, Ward SM, Wilson RE, Cunningham ME. Abstract presented at SOT Annual Meeting 1999.
  44. Trempus CS, Ward SM, Farris G, Malarkey D, Faircloth RS, Cannon RE, Mahler JF. Association of v-Ha-ras transgene expression wit development of erythroleukemia in Tg.AC transgenic mice. Amer J Path. 1998 July;153(1)247-53.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9665485) Exit NIEHS
  45. Morgan DL, Shines CJ, Jeter SP, Blazka ME, Elwell MR, Wilson RE, Ward SM, Price HC, Moskowitz PD. Comparative pulmonary absorption, distribution, and toxicity of copper gallium diselenide, copper indium diselenide, and cadmium telluride in Sprague-Dawley rats. Toxicol Appl Pharmacol. 1997 Dec;147(2):399-410.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9439735) Exit NIEHS
  46. Chapin RE, Harris MW, Davis BJ, Ward SM, Wilson RE, Mauney MA, Lockhart AC, Smialowicz RJ, Moser VC, Burka LT, Collins BJ. The effects of perinatal/juvenile methoxychlor exposure on adult rat nervous, immune and reproductive system function. Fundam Appl Toxicol. 1997 Nov;40(1):138-157.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9398496) Exit NIEHS

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Last Reviewed: January 12, 2009