| Development and Commercialization of Agents That Regulate Proliferation and Survival of Stem Cells |
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Institute : National Institute of Neurological Disorders and Stroke (NINDS)
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| Description of Technology/Invention :
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The National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health (NIH) seeks a Cooperative Research and Development Agreement (CRADA) Collaborator to work with NINDS in the development, manufacture and commercialization of agents than inhibit or induce phosphorylation of a key regulator of proliferation and survival of stem cells and precursor cells.
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| Potential Areas of Application : |
∙ Clinical treatment for stroke and other neurodegenerative diseases by administration of agents that promote stem cell survival and proliferation
∙ Increased generation of stem cells in vitro
∙ Diagnostic assay for cancer to determine the phosphorylation state of the protein in tumors
∙ Screening assays for agents that promote proliferation of stem cells or inhibit
proliferation of cancer cells
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| Main Advantages of Technology/Invention
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∙ Treatment for neurodegenerative disorders such as Parkinson’s disease or stroke
∙ Prognostic marker to help determine response of individuals with cancer
∙ Commercial suppliers or large-scale users of stem cells
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| Current State of Development : |
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| Patent Status : |
| U.S. Provisional Application No. 60/715,935 filed 08 Sep 2005 |
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| NIH Reference Number: |
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| Contact Information : |
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| Last Updated: 7/25/2006 |
