Welcome to the Dog Genome Project at the National Human Genome Research Institute (formerly at the Fred Hutchinson Cancer Research Center). We are working to develop resources necessary to map and clone canine genes in an effort to utilize dogs as a model system for genetics and cancer research.

A Single IGF1 Allele Is a Major Determinant of Small Size in Dogs - a paper in Science Magazine.

• Click here for the abstract or the full length paper.

• For additional questions about this study, please see our Frequently Asked Questions page.

Health Update for the Malignant Histiocytosis Study
Owners of dogs who have taken part of the Malignant Histiocytosis Study can submit updates of their dog's health. For more information about current studies of Transitional Cell Carcinoma, Malignant Histiocytosis, Squamous Cell Carcinoma, Hemangiosarcoma, and T-Cell Lymphoma please contact us at: dog_genome@mail.nih.gov.

Genetic Structure of the Purebred Domestic Dog - a paper in Science Magazine.
A phylogenetic analysis of the genetic relationships within and between a diverse collection of breeds. See References for the paper citation.

• Click here for the abstract or the full length paper.

• Supporting information for this paper can be found in Supplemental Info For Recent Publications.

• For additional questions about this study, please see our Frequently Asked Questions page.

A 1 Mb Resolution Radiation Hybrid Map of the Canine Genome
A 3270 marker Canine Radiation Hybrid Map with Minimal Screening Set 2. Info on markers and radiation hybrid maps can be found here. This work includes markers added to the canine genome since the Integrated Cytogenetic, Linkage and RH Map below.

Canine Cytogenetic, Linkage, and Radiation Hybrid Map (2001)
An integrated 1800 marker Canine Linkage and Radiation Hybrid Map, anchored to all chromosomes by FISH. Info on markers and maps can be found here. This map includes the most recent version of the meiotic linkage map.

Genome Map History
Past versions of the Canine genomic map.

Supplemental Information for Recent Publications
Links to supporting methods, tables, and figures from recently published NHGRI Dog Genome Project and other Ostrander Group studies.

Methods and Protocols
Methods and protocols used in building the canine genomic map.

References
References to NHGRI Dog Genome Project publications in Canine research.

Links
Links to other canine and genome information resources.

Information for Dog Owners
An overview of the Dog Genome Research Project geared towards dog owners.

• Send questions and comments to dog_genome@mail.nih.gov