NINDS Neuroscience Funding Announcements

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Mechanisms of Orofacial Pain: Anatomy, Genomics, and Proteomics
Release Date: November 19, 2003
Announcement Number: RFA-DE-05-004
Application Receipt Date:
May 14, 2004   
Letter of Intent Date: April 19, 2004

Funding Contact: Linda Porter, Ph.D.
Program Area: Systems and Cognitive Neuroscience

Brief Description:
The purpose of this RFA is to encourage the use of genomic and proteomic approaches and imaging techniques to clarify the molecular events involved in: 1) acute orofacial pain, 2) the transition from unrelieved acute pain to chronic pain (i.e. neuroplasticity), 3) neuronal hyperexcitability as manifested by hyperalgesia and allodynia, and 4) chronic orofacial pain disorders of an inflammatory and neuropathic origin. This improved understanding could lead to new therapeutic interventions to effectively treat chronic pain conditions. Collaborative projects involving interdisciplinary teams of investigators are strongly encouraged. This Request for Applications contributes to the goals of the NIH Pain Consortium, which is co-chaired by NIDCR, NINDS, and the National Institute of Nursing Research (NINR).

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