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Non-Human Lentiviral Models of the Neurological Complications of AIDS (R01)
Release Date: March 25, 2005
Announcement Number: PAS-05-078
Application Receipt Date:
May 1, 2005
September 1, 2005
January 2, 2006
May 1, 2006
September 1, 2006
January 2, 2007
Funding Contact: NINDS Funding
Program Area: Neural Environment
Brief Description:
The National Institute of Neurological Disorders and Stroke (NINDS), the National Institute on Drug Abuse (NIDA) and the National
Institute of Mental Health (NIMH) invite research grant applications aimed at developing non-human lentiviral in vivo model
systems for study of the neurologic complications of AIDS, with or without a history of drug use. Recent advances in the development
of the SIV model system highlight the power of animal model systems for study of the mechanisms underlying the pathology associated
with lentiviral infection in the nervous system. These models will be key for developing therapeutic approaches for the treatment
of patients suffering from NeuroAIDS and for understanding the basic biology of infection with HIV/AIDS.
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