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Genetic and Genomic Analyses of Xenopus
Release Date: September 20, 2005
Announcement Number: PAR-05-166
Application Receipt Date:
January 18, 2006
January 18, 2007
Funding Contact: Danilo Tagle, Ph.D.
Program Area: Neurogenetics
Brief Description:
For the past few years, the international research community has been generating genetic and genomic data and reagents for
the model systems, X. tropicalis and X. laevis . These products include: 1) cDNA libraries and EST sequences, 2) UniGene
clusters, 3) full-insert cDNA clones and sequences, 4) a genetic map, 5) genomic libraries and genomic sequences, 6) a physical
map, 7) genome sequence, 8) microarrays, and 9) transgenic and mutant animals (see http://www.nih.gov/science/models/xenopus).
These diverse data and reagents are being generated by investigators from several different research communities, including
geneticists, gene sequencers, gene mappers, cell biologists, developmental biologists, and bioinformatics experts. These materials
and data can now be used to enhance Xenopus' role as a model system. This PAR solicits applications from investigators in
these different fields to combine these data, reagents and methodologies to elucidate the genetic basis of cell biological
events, including embryonic development and organogenesis.
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