NINDS Neuroscience Funding Announcements

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Precursor Cells in Skeletal Muscle Repair and Hypertrophy
Release Date: July 25, 2002
Announcement Number: PA-02-136
Application Receipt Date:
February 1, 2003
June 1, 2003
October 1, 2003
February 1, 2004
June 1, 2004
October 1, 2004
February 1, 2005
June 1, 2005
October 1, 2005
February 1, 2006   

Funding Contact: John Porter, Ph.D.
Program Area: Channels, Synapses and Neural Circuits

Brief Description:
encourage investigator-initiated research grant applications to isolate, characterize and identify precursor cells required for normal growth and repair of injured, aged, or diseased muscle. Goals include determining factors responsible for migration, proliferation, and differentiation of precursor cells following muscle injury or increased exercise. This includes characterizing molecular controls responsible for the quiescence of muscle satellite cells and determining metabolic and motile properties of satellite cells while they are quiescent. Researchers are encouraged to develop strategies using muscle satellite and stem cells in therapies for human disease and enhanced repair of muscle injury and as cellular vectors of genes.

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