Membrane Biology Section, MPTB
NATIONAL INSTITUTES OF HEALTH/NIDCR
BUILDING 10 ROOM 1A01
10 CENTER DR MSC 1190
BETHESDA MD 20892-1190
Phone: (301) 402-1060
Fax: (301) 402-1228
E-mail: Dr. R. James Turner
Research Interests
Structure and function of membrane transport systems.
Education
B.Sc. 1967 Queen's University, Canada
M.Sc. 1968 University of Toronto, Canada
Ph.D. 1971 University of Toronto, Canada
Recent Publications
Dohke, Y. and Turner, R.J. Evidence that the transmembrane biogenesis of aquaporin 1 is cotranslational in intact mammalian cells. J. Biol. Chem. 277:15215-15219 (2002).
Dehaye, J.P., Nagy, A., Premkumar, A. and Turner, R.J. Identification of a functionally important conformation-sensitive region of the secretory Na+-K+-2Cl- cotransporter (NKCC1).J Biol Chem. 278:11811-7 (2003).
Dohke, Y., Oh, Y.S., Ambudkar, I.S. and Turner, R.J. Biogenesis and topology of the transient receptor potential Ca2+ channel TRPC1. J. Biol. Chem. 279:12242-8 (2004).
Tanimura, A., Nezu, A., Morita, T., Turner, R.J., and Tojyo, Y. Fluorescent biosensor for quantitative real-time measurements of inositol 1,4,5-trisphosphate in single living cells J. Biol. Chem. 279:38095-8 (2004).
Oh, Y.S. and Turner, R.J. Evidence that the C-terminus of human presenilin 1 is located in the extra-cytoplasmic space. Am. J. Physiol. 289:C576-81 (2005).
Oh, Y.S. and Turner, R.J. Topology of the C-terminal fragment of human presenilin 1. Biochemistry 44:11821-8 (2005).
Oh, Y.S. and Turner, R.J. Effect of γ-secretase inhibitors on muscarinic receptor-mediated calcium signaling in human salivary gland epithelial cells. Am. J. Physiol. Cell Physiol. 291:C76-82 (2006).
Gerelsaikhan, T., Parvin, M.N., Turner, R.J. Biogenesis and topology of the secretory Na+-K+-2Cl- cotransporter NKCC1 studied in intact mammalian cells. Biochemistry 45:12060-7 (2006).