Membrane Biology and Protein Processing Study Section [MBPP]

[MBPP Membership Roster] [MBPP Meeting Rosters]


The Membrane Biology and Protein Processing [MBPP] Study Section reviews applications primarily concerned with protein synthesis, processing, maturation, targeting and degradation as well as membrane structure, function and trafficking.  These topics are investigated using cell biological, molecular, biochemical, morphologic, electrophysiological and structural approaches and employing various model systems  including yeast, flies, worms, plants, cultured cells and mice.  Specific areas covered by MBPP include:

 

  • Molecular regulation of vesicle-mediated trafficking along the secretory and endocytic pathways with an emphasis on the mechanisms of cargo sorting as well as vesicle formation, targeting and fusion
  • Regulation, functions and mechanisms of the ubiquitin/proteasome system
  • Mechanisms and regulation of protein synthesis, processing, folding (chaperones), quality control (ERAD), targeting, and degradation
  • Post-translational modifications with an emphasis on glycosylation, ubiquitination, lipidation and phosphorylation
  • Membrane biogenesis, structure, and function, with an emphasis on the organization and interactions of proteins, carbohydrates, and lipids in cell membranes; metabolism and trafficking of lipids; and function of lipid domains
  • Organelle biogenesis, structure, function and dynamics with an emphasis on chloroplasts, mitochondria and peroxisomes
  • Transport of small molecules across membranes via channels, transporters and gap junctions


Study sections with most closely related areas of similar science listed in rank order are:

Synapses, Cytoskeleton, and Trafficking [SYN]
Macromolecular Structure and Function B [MSFB]
Cell Structure and Function [CSF]
Biochemistry and Biophysics of Membranes [BBM]
Molecular Genetics A [MGA]


 



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