NIAID Category A, B, and C Priority Pathogens
Category A
- Bacillus anthracis (anthrax)
- Clostridium botulinum toxin (botulism)
- Yersinia pestis (plague)
- Variola major (smallpox) and other related pox viruses
- Francisella tularensis (tularemia)
- Viral hemorrhagic fevers
- Arenaviruses
- LCM, Junin virus, Machupo virus, Guanarito virus
- Lassa Fever
- Bunyaviruses
- Hantaviruses
- Rift Valley Fever
- Flaviruses
- Filoviruses
Category B
- Burkholderia pseudomallei
- Coxiella burnetii (Q fever)
- Brucella species (brucellosis)
- Burkholderia mallei (glanders)
- Chlamydia psittaci (Psittacosis)
- Ricin toxin (from Ricinus communis)
- Epsilon toxin of Clostridium perfringens
- Staphylococcus enterotoxin B
- Typhus fever (Rickettsia prowazekii)
- Food- and Waterborne Pathogens
- Bacteria
- Diarrheagenic E.coli
- Pathogenic Vibrios
- Shigella species
- Salmonella
- Listeria monocytogenes
- Campylobacter jejuni
- Yersinia enterocolitica)
- Viruses (Caliciviruses, Hepatitis A)
- Protozoa
- Cryptosporidium parvum
- Cyclospora cayatanensis
- Giardia lamblia
- Entamoeba histolytica
- Toxoplasma
- Fungi
- Additional viral encephalitides
- West Nile Virus
- LaCrosse
- California encephalitis
- VEE
- EEE
- WEE
- Japanese Encephalitis Virus
- Kyasanur Forest Virus
Category C
Emerging infectious disease threats such as Nipah virus and additional hantaviruses.
NIAID priority areas:
- Tickborne hemorrhagic fever viruses
- Crimean-Congo Hemorrhagic fever virus
- Tickborne encephalitis viruses
- Yellow fever
- Multi-drug resistant TB
- Influenza
- Other Rickettsias
- Rabies
- Prions
- Chikungunya virus
- Severe acute respiratory syndrome associated coronavirus (SARS-CoV)
- Antimicrobial resistance, excluding research on sexually transmitted organisms*
- Research on mechanisms of antimicrobial resistance
- Studies of the emergence and/or spread of antimicrobial resistance genes within pathogen populations
- Studies of the emergence and/or spread of antimicrobial-resistant pathogens in human populations
- Research on therapeutic approaches that target resistance mechanisms
- Modification of existing antimicrobials to overcome emergent resistance
- Antimicrobial research, as related to engineered threats and naturally occurring drug-resistant pathogens, focused on development of broad-spectrum antimicrobials
- Innate immunity, defined as the study of nonadaptive immune mechanisms that recognize, and respond to, microorganisms, microbial products, and antigens
- Coccidioides immitis (added February 2008)
- Coccidioides posadasii (added February 2008)
*NIAID Category C Antimicrobial Resistance—Sexually Transmitted Excluded Organisms
Bacterial vaginosis, Chlamydia trachomatis, Cytomegalovirus, Granuloma inguinale, Hemophilus ducreyi, Hepatitis B virus, Hepatitis C virus, Herpes Simplex virus, Human immunodeficiency virus, Human papillomavirus, Neisseria gonorrhea, Treponema pallidum, Trichomonas vaginalis
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