Summaries & Associations of Study Results
TR-321 Bromodichloromethane
Target Organs and Levels of Evidence
NTP Technical Report Number 321
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| BROMODICHLOROMETHANE 75-27-4 | 08/19/86 | SOLVENT. CHEMICAL INTERMEDIATE. FLAME RETARDANT. (TDB) | Gavage R: 0,50,100 MM:0,25,50 FM: 0,75,150 MG/KG/50 PER GROUP | T.S.I. Mason Laboratories, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: CLEAR EVIDENCE | KIDNEY TUBULAR CELL: ADENOMA 0/50 1/50 3/50; ADENOCARCINOMA 0/50 0/50 10/50; COMBINED 0/50 1/50 13/50 | |||
| INTESTINES: ADENOMATOUS POLYP 0/50 3/50 33/50; ADENOCARCINOMA 0/50 11/50 38/50 | ||||
| FR: CLEAR EVIDENCE | KIDNEY TUBULAR CELL: ADENOMA 0/50 1/50 6/50; ADENOCARCINOMA 0/50 0/50 9/50; COMBINED 0/50 1/50 15/50 | |||
| INTESTINES: ADENOMATOUS POLYP 0/46 0/50 7/47; ADENOCARCINOMA 0/46 0/50 6/47 | ||||
| MM: CLEAR EVIDENCE | KIDNEY TUBULAR CELL: ADENOMA 1/49 2/50 6/50; ADENOCARCINOMA 0/49 0/50 4/50; COMBINED 1/49 2/50 9/50 | |||
| FM: CLEAR EVIDENCE | LIVER: ADENOMA 1/50 13/48 23/50; CARCINOMA 2/50 5/48 10/50 | |||
Web page last updated on October 25, 2007
