Synapses, Cytoskeleton and Trafficking Study Section [SYN]

[SYN Membership Roster] [SYN Meeting Rosters]


The Synapses, Cytoskeleton and Trafficking [SYN] Study Section reviews applications on the basic cell biology of nerve, muscle and other excitable cells, including synaptic plasticity, protein and organelle trafficking, cell surface and extracellular matrix molecules in cell recognition and function, and cytoskeletal functions across the life span. Emphasis is on fundamental mechanisms of excitable cell function, including those relevant to disease processes.

  • Formation, regulation, maintenance, and dynamics of synaptic structure and function in the central and peripheral nervous systems.
  • Molecular neuronal mechanisms of endocytosis, exocytosis and membrane recycling; protein assembly, folding and targeting; organelle, protein, and mRNA localization and trafficking.
  • Transcriptional and translational regulation as they relate to synaptic function and plasticity.
  • Structure, function, modification, assembly and regulation of cytoskeletal proteins and molecular motors; axonal and dendritic transport; neuronal polarity, growth cones, and structural plasticity; cytoskeletal pathology; the regulation and role of the proteosome/ubiquitin system in these processes.
  • Cell surface, extracellular matrix, transmembrane components, and their function; cell recognition as it relates to synaptic assembly and function.

Study sections with most closely related areas of science listed in rank order are:

Neurodifferentiation, Plasticity and Regeneration [NDPR]
Neurotransporters, Receptors, Channels and Calcium Signaling [NTRC] 
Cellular and Molecular Biology of Neurodegeneration [CMND]
Biophysics of Neuronal Systems [BPNS]  
Molecular Neuropharmacology and Signaling [MNPS]

 



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