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September 2005 Director's Status Report

Budget and Appropriations

FY 2006 President's Budget

The FY 2006 President’s Budget for NIA (including AIDS) is $1,057,203,000, an increase of 0.5 percent over the FY 2005 appropriation amount of $1,051,990,000. Funding for AIDS- related research decreases from $5,459,000 in FY 2005 to $5,443,000 in FY 2006, a decrease of 0.3 percent. Also included in the FY 2006 request is NIA’s support for the trans-NIH Roadmap initiatives, estimated at 0.89 percent of the FY 2006 budget request ($9.454 M).

The FY 2006 President’s Budget for NIH (including AIDS) increases from $28,594,357,000 in FY 2005 to $28,740,073,000 in FY 2006, an increase of 0.5 percent.

Overall Budget Policy

NIH’s highest priority is the funding of medical research through research project grants (RPGs). Support for RPGs allows NIH to sustain the scientific momentum of investigator-initiated research while pursuing new research opportunities. For NIA, the average cost of competing RPGs will be $400,000 in FY 2006. While no inflationary increases are provided for direct, recurring costs in non-competing RPGs, NIA will honor commitments to programmatic increases.

The continuing vibrancy of medical research depends on attracting, training, and retaining the best and the brightest individuals to pursue careers in biomedical and behavioral research. In the FY 2006 request, most stipend levels for individuals supported by the Ruth L. Kirschstein National Research Service Awards are maintained at the FY 2005 levels. To help prevent the potential attrition of our next generation of highly trained post-doctoral trainees, stipend levels for those with one to two years of experience are increased by 4.0 percent. In addition, individual post-doctoral fellows will receive an increase of $500 in their institutional allowance for rising health benefit costs. The need for increased health benefits is particularly acute for these post-doctoral trainees, who, because of their age and stage of life are more likely to have family responsibilities. Because NIH believes it is important to support and compensate adequately those who are participating in these training programs, the increases in stipends and health insurance are financed within the FY 2006 request by reducing the number of Full-Time Training Positions so that the programs can continue to attract and retain the trainees most likely to pursue careers in biomedical, behavioral and clinical research. NIA will support 541 pre- and postdoctoral trainees in full-time training positions.

NIA FY 2006 President’s Budget - Mechanism Discussion

The FY 2006 request includes funding for 1,422 research project grants, compared to 1,439 in FY 2005 and 1,392 in FY 2004. Of these 1,422 awards, 390 will be competing research project grants and 1,032 will be noncompeting awards. In addition, the request includes funding for 87 SBIR/STTR grants.

Funding for the Centers mechanism increases by 1.3 percent over the FY 2005 Appropriation.

The FY 2006 request includes an increase of 1.8 percent over the FY 2005 Appropriation for Other Research.

Funding for Contracts in FY 2006 increases by 1.0 percent over the FY 2005 Appropriation.

The FY 2006 request includes a 1 percent increase above the FY 2005 Appropriation for Intramural Research and a 0.5 percent increase above the FY 2005 Appropriation for RMS.

(Contact: Mr. Patrick Shirdon, BO, 301-496-9147)

Legislative Update

I. Significant Legislative/Executive Action

President’s Proposed FY 2006 Budget and Senate and House Appropriations Bills for NIH/NIA - The House and Senate have passed the FY 2006 Labor, Health and Human Services, Education and Related Agencies Appropriations bills. The two measures are different and will have to be reconciled in conference. The House measure appropriates the President’s Budget amount of $1,057,203,000 for NIA. The Senate has approved a 3.16 percent increase over the President’s Budget or $1,090,600,000. The FY 2006 President’s Budget for NIA is an increase of 0.5 percent over the FY 2005 Appropriation amount of $1,051,990,000.

II. Congressional Briefings and Hearings

  • Senate HELP Committee Briefing on Aging Related Statistics - On May 3, at the request of Nancy Falk, Legislative Fellow on Aging and Health to Senator Jeff Bingaman (D-NM), NIA participated in a briefing on aging-related statistics. Dr. Richard Suzman, Associate Director, Behavioral and Social Research, NIA, discussed research on population aging and implications for the future.

  • Alliance for Aging Research Congressional Breakfast - On May 17, at the request of the Alliance for Aging Research, Dr. Chhanda Dutta, Chief, Clinical Gerontology Branch, Geriatrics and Clinical Gerontology Program, NIA, participated in a congressional briefing on "Prevalent Diseases that Remain in the Shadows: Vertigo, Sarcopenia, and Restless Leg Syndrome."

  • Senate Staff on Aging Research - On June 1, at the request of Casey Hemard, Senior Investigator, Senate Special Committee on Aging, Dr. Judy Salerno, Deputy Director, NIA, provided an overview of aging-related research.

III. Professional Organization and International Outreach Activities

  • On September 2, NIA staff will participate on a panel at the Meals on Wheels Messages Association of America Annual Convention in Richmond, Virginia, to discuss the development of the NIA, Administration on Aging, and Meals on Wheels Association of America partnership booklet on Safe Use of Medicines and how to successfully market health messages. This brochure also received a 2005 National Mature Media Award.

  • NIA will host a booth exhibit at the United States Senate Elder Care Fair on September 8 from 9:30 a.m. to 4:00 p.m. in Room 902, Hart Senate Office Building, Washington, DC, 20510

  • NIA researchers will present at a Friends of NIA Hill event on September 20 in Washington, DC.

(Contact: Dr. Tamara Jones, NIA/OD, Ph: 401-451-8835)

Staff Changes

Dr. Suzana Petanceska joined the Neuroscience and Neuropsychology of Aging (NNA) Program as a Health Scientist Administrator for the Neurobiology of Aging and the Dementias Branches in July. Dr. Petanceska holds a Ph.D. in Pharmacology from New York University. Her postdoctoral training at the Rockefeller University, New York, NY, was in Molecular and Cellular Neuroscience with an emphasis on the molecular basis of Alzheimer’s disease pathogenesis. Prior to coming to the NIA, Dr. Petanceska was an Assistant Professor of Psychiatry and Pharmacology at the Nathan Kline Institute in Orangeburg, NY, and New York University, New York, NY. Her research was on the role of disrupted sterol metabolism in the development of Alzheimer’s amyloidosis and the mechanisms by which estrogens and cholesterol-lowering drugs might exert neuroprotection. She has extensive experience in preclinical studies using various AD-relevant transgenic mouse models.

Dr. Laurie Ryan joined the NNA Program on September 6 as a Health Scientist Administrator for the Alzheimer’s disease clinical trials program. Dr. Ryan has a Ph.D. in clinical psychology with a specialty in clinical neuropsychology. Since 1999 she has been Assistant Director for Research and a neuropsychologist at the Defense and Veterans Brain Injury Center, Department of Neurology, Walter Reed Army Medical Center, Washington, DC, and also Assistant Professor of Neurology at the F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD.

Dr. Nina Silverberg recently joined NNA as Assistant Director of the Alzheimer’s Disease Centers (ADC) Program. Dr. Silverberg received her Ph.D. in Cognitive Psychology from the University of Arizona and worked in research at Massachusetts General Hospital, Temple University Department of Neurology and most recently as a Clinical Research Scientist at the Sun Health Research Institute in Phoenix and on the staff of the Arizona Alzheimer’s Disease Center where she coordinated the Native American Outreach Program. She was principal investigator on an Alzheimer’s Association grant to assess cultural fairness of neuropsychological assessment instruments used with Native American populations. At NNA, in addition to her responsibilities with the ADCs, she will continue to work with programs related to cultural diversity and assessment of cognition.

Dr. Alfonso R. Latoni accepted a position as Scientific Review Administrator (SRA) in the Health of the Population (HOP) Integrated Review Group (IRG), Division of Clinical and Population-Based Studies, at the Center for Scientific Review (CSR). Dr. Latoni joined CSR in August, after three years as an SRA in the Scientific Review Office of the NIA.

Ms. Lorraine Fitzsimmons, Chief of NIA's Office of Planning and Evaluation (OPAE), retired on August 1 from Federal service. A recruitment for her replacement has been initiated. In the interim, Dr. Tamara Jones, Legislative and International Activities, will serve as Acting Chief of OPAE.

Mr. Patrick Shirdon, Chief, Financial Management Branch, NIA, is leaving NIA to accept a position as Deputy Executive Officer at the National Institute of Mental Health (NIMH) on October 1.

Institute-Sponsored Meetings, Workshops, Conferences, and Public Information Activities

I. Meetings Held

The Report of the National Institutes of Health (NIH) Critical Evaluation Study for the Cognitive and Emotional Health Project -The Neuroscience and Neuropsychology of Aging (NNA) Program of NIA along with NIMH and the National Institute of Neurological Disorders and Stroke (NINDS) sponsored a symposium highlighting the trans-NIH initiative, "The Cognitive and Emotional Health Project," on June 21, 2005, in Washington, DC. The symposium was held as an ancillary event to the Alzheimer’s Association International Conference on Prevention of Dementia: Early Diagnosis and Intervention. The NIH Cognitive and Emotional Health Project (CEHP) has been a joint venture of the NIA, the NIMH, and the NINDS. The goals of the project have been (1) to assess the state of longitudinal and epidemiological research on demographic, social, and biologic determinants of cognitive and emotional health among adults, (2) to determine how these pathways may reciprocally influence each other, (3) to identify gaps in that knowledge, and (4) to promote further research as deemed necessary to resolve inconsistencies and to accelerate the pace of scientific advances in the fields of cognition and emotion. The overarching goal was to determine how cognitive and emotional health can be maintained and enhanced as people grow older by unearthing the risk and preventive factors for cognitive and emotional dysfunction.

A central activity of the CEHP was the execution of the Critical Evaluation Study, the purpose of which was to critically evaluate the extant literature and resulting findings from longitudinal studies that targeted factors involved in the maintenance of cognitive and/or emotional health in the adult. A blue-ribbon committee of extramural and intramural experts formulated the structure of the Critical Evaluation Study, set the criteria for inclusion of studies to be examined, conducted an exhaustive search of relevant studies and resultant publications, and analyzed the outcomes of the published research. The purpose of this symposium was to present the structure and outcomes of the study to the clinical and research communities and to offer suggestions for future research directions and opportunities. (Contact: Dr. Molly Wagster, NNA, Ph: 301-496-9350 or wagsterm@nia.nih.gov <mailto:wagsterm@nia.nih.gov>)

Neuroeconomics and Aging - On August 12 and 26, 2005, two conference calls were held with leaders in the fields of neuroeconomics and decision science to explore how the Behavioral and Social Research Program (BSR) can develop multi-level economic research aimed at understanding how older adults negotiate important life decisions regarding retirement, Medicare, and healthcare management. Colleagues from NNA and the National Science Foundation (NSF) participated. Discussion focused on areas of research that explore interactions among psychological, physiological, social, and economic factors. Eleven researchers from the fields of psychology, neuroscience, economics, and decision making prepared short statements of research ideas which served as the basis for the discussions. Plans were made to develop ideas from these (and potentially further) discussions into an initiative on neuroeconomic and integrative science approaches to studying economic and healthcare decision-making in older adults. (Contacts: Drs. Lis Nielsen, Jeff Elias, and John Phillips, BSR, Ph: 301-496-3136)

II. Meetings Planned

Expert Meeting on the Future of the National Long-term Care Survey - On October 7, 2005, the Committee on Population and the Committee on National Statistics of the NAS National Research Council will host this exploratory meeting in Washington, DC, with funding provided through an NIA/BSR inter-agency agreement. Its purpose is to discuss past and future uses of data from the National Long-term Care Survey for research on disability trends and dynamics among older Americans, in both community and institutional populations. Topics discussed will include comparability of data over time, the uses of panel data, and trends and gaps in the availability of data on disability and its precursors and consequences. Participants will include epidemiologists, demographers, statisticians, gerontologists, and other researchers and officials concerned with disability research. (Contact: Dr. John Haaga, BSR, Ph: 301-496-3131)

Decision Making and Aging - On November 29 in Washington, DC, the National Academy of Sciences, in conjunction with BSR, will conduct a meeting on decision making and aging. Topics to be discussed include: (1) Neural basis of decision making in older adults, (2) Design of health decision aids for older adults, (3) Role of affect and emotion in decision making by older adults, (4) Effects of age and social context on decision making, and (5) Aging and decision making competence. A panel will comment on papers prepared in advance. The meeting is exploratory to help develop directions for future NIA research in this area. (Contact: Dr. Jeff Elias, BSR, Ph: 301-402-4156)

Signaling Defects in the Aging Immune System - An exploratory workshop on Signaling Defects in the Aging Immune System is currently being planned and is scheduled to be held on October 24-25, 2005 in Potomac, MD. The purpose of the workshop is to bring together investigators with expertise in signal transduction, lipid raft formation and lipid metabolism to discuss recent findings on how aging affects these processes. The workshop will help to identify important gaps in knowledge which will aid in focusing future research efforts. The workshop is also expected to promote interaction between researchers working in these different areas of research. A report of the meeting will be made available to NIA staff. (Contact: Dr. Rebecca Fuldner, BAP, Ph: 301-496-6402)

Expert Meeting on Identifying Interventions to Accelerate Disability Decline in Elderly Populations - The Committee on Population of the NAS National Research Council is organizing an exploratory meeting to be held in November 2005 in Washington, DC. Funding will be provided through an NIA/BSR inter-agency agreement. The purpose of the meeting is to discuss what is known about modifiable risk factors for major sources of disability in the elderly, lessons from previous multi-level interventions, and promising new areas for interventions to accelerate the disability decline. Participants will include economists, psychologists, epidemiologists, public health specialists, and health policy researchers. (Contact: Dr. John Haaga, BSR, Ph: 301-496-3131)

NIA Workshop on Molecular and Cellular Basis of Cognitive Aging - The NNA Program is sponsoring an exploratory workshop on the state of molecular and cellular neuroscience approaches and advances in the study of cognitive aging that will take place in the fall 2005 (date TBD) in Bethesda, MD. Significant and compelling advances are being made each day in the field of molecular neuroscience of learning, memory, and other cognitive processes. NIA has been fortunate to support several research programs that direct these approaches to the issue of cognitive aging in the hopes of reaching a better understanding of the basis of cognitive change with age and of directing preventions or interventions toward this problem. Despite these longstanding and productive research programs, there is not an influx of young investigators with a background in molecular and cellular cognitive neuroscience into the field of aging. The objective of this proposed workshop is (1) to invite young investigators (post-docs, junior investigators) in the field of molecular and cellular cognitive neuroscience (but who are not currently applying their knowledge to questions of aging), (2) to highlight through presentations by funded investigators the research accomplishments of their programs and recent progress, (3) to hold a half-day poster session in which the young investigators can discuss their work with senior investigators in a one-on-one basis, (4) to hold a half day session with the senior investigators to determine the impediments to young investigators in the application of their training to questions of cognitive aging. (Contact: Dr. Molly V. Wagster, NNA, Ph: 301-496-9350, wagsterm@nia.nih.gov <mailto:wagsterm@nia.nih.gov>)

Meeting to Evaluate Alzheimer’s Disease Research and Directions for the Future - The NNA Program is planning to hold a large advisory meeting in 2006 with scientists from a broad range of disciplines to evaluate the current state of Alzheimer’s disease research and suggest research directions for the future. A smaller group of investigators will be asked to participate in a "summit meeting" the fall of 2005 to plan the agenda for the larger meeting. (Contact: Dr. Neil Buckholtz, NNA, Ph: 301-496-9350)

General Information/Staff Awards

NIH Invited Electronic Grant Applications for June and July 

Over the past 22 months, NIH’s electronic Research Administration (eRA) has successfully received more than 100 new and competing grant applications from 30 institutions.

NIH invites electronic submission of modular R01, R03 and R21 grant applications. All SBIR applications must be submitted electronically starting December 1.

Currently, there are two ways an applicant can submit grants electronically to NIH:

  1. Through a service provider-one of six companies that have developed high-end software systems compatible with NIH systems.
  2. Through a direct system-to-system interface that an institution can develop with NIH.

At the end of the year, applicants will be able to submit through www.Grants.gov, a federal Web portal that provides grant info and the ability to apply for grants from 26 federal agencies. For updates on NIH’s progress with www.Grants.gov and detailed information on electronic submission, visit NIH Eletronic Research Administration.

Awards

Dr. Richard Suzman, Associate Director, BSR, was honored with an NIH Director’s Award on July 14, 2005.

The Office of Communications and Public Liaison (OCPL) won the following publication awards:

  • APEX Award for Publication Excellence for NIA Publications CD-ROM 
  • Mature Media, Brochure/Booklet category, Silver Award for What’s Your Aging IQ?
  • Mature Media, Brochure/Booklet category, Bronze Award for Safe Use of Medicines
  • Mature Media, Annual Report category, Silver Award for 2003 Progress Report on AD
  • Mature Media, Miscellaneous Publication category, Silver Award for Working with Your Older Patient

(Contact: Ms. Vicky Cahan, OCPL, Ph: 301-496-1752)

NIA News Releases/Outreach

Over 10 press releases were distributed between April and August 2005, generating over 200 clips and reaching nearly 21 million people in print, the most current NIA press releases can be found online at: http://www.nia.nih.gov/NewsAndEvents/PressReleases/.

  • Diane Rehm Show on Alzheimer’s Disease: Nationally syndicated radio show featuring Dr. Marcelle Morrison-Bogorad as a guest aired April 28; prompted triple usual level of calls to ADEAR 
  • The Media Network conducted an outreach campaign promoting Conversando con su Medico; resulted in requests for 36,914 books and 247 promotional posters
  • NIH Science in the Cinema: Dr. Marcelle Morrison-Bogorad presented on AD, in conjunction with a showing of "The Notebook"

(Contact: Ms. Vicky Cahan, OCPL, Ph: 301-496-1752)

Publications

BSR updated its informational CD in July of 2005.

New Publications

The following new publications were printed and disseminated:

Aging Hearts and Arteries: A Scientific Quest

Genes, Lifestyles, and Crossword Puzzles: Can AD be Prevented?

There’s No Place Like Home-For Growing Old: Tips from the NIA

Connections, Vol. 12, No. 3-4

NIA Exercise Video (DVD format)

The following publications were updated or reprinted:

Age Pages (Spanish): Stroke, HIV/AIDS, Diabetes

Age Pages: Smoking, Good Nutrition, Depression, Osteoporosis

Age Page CD-ROM

NIA Publications CD-ROM

NIA Exercise Video (VHS)

(Contact: Ms. Vicky Cahan, OCPL, Ph: 301-496-1752)

To receive a copy of any publications, e-mail niaic@jbs1.com order online at www.niapublications.org, or call the NIA Information Center at Ph: 1-800-222-2225.

NIH Senior Health

  • Seven new topics were added to the NIHSeniorHealth website, bringing to 20 the number of topics the site currently offers to the public. New topics are, in conjunction with the National Eye Institute: Low Vision, Age-related Macular Degeneration, Diabetic Retinopathy, Glaucoma, Cataracts, and, in conjunction with the National Institute on Dental and Craniofacial Disorders: Problems with Taste, Problems with Smell. An additional 12 new topics are currently in development.

  • OCPL received an Express Evaluation Award to evaluate a program to train older adults to search for health information on the Web using NIHSeniorHealth (<http://NIHSeniorHealth.gov>) and MedlinePlus (<http://MedlinePlus.gov/>) as models. The evaluation will start in August.

  • From April to June (3rd quarter) there were over 170,000 unique visitors to the website - representing a 21 percent increase over the 2nd quarter.

(Contact: Ms. Vicky Cahan, OCPL, Ph: 301-496-1752)

Meetings and Exhibits

NIA and ADEAR publications were distributed at the American College of Physicians, Montgomery County Women’s Fair, ADC/ADCS meetings, National Women’s Health Week observance at NIH Clinical Center, NIH Take Your Child to Work Day, NIA Mini-Med School at the Smithsonian, Assisted Living Federation of America, Secretary’s Walk on the Mall, National Hispanic Council on Aging, Family Caregiver Expo, NIH Share the Health Fair, American Geriatrics Society, National Rural Health Association, Medical Library Association, American Academy of Physician Assistants, National Senior Games, Endocrine Society, American Academy of Nurse Practitioners, Alzheimer’s Association Prevention Conference, National Association of Nutrition and Aging Services Programs, Summer Institute on Aging Research, National Association of Hispanic Journalists, National Black Nurses Association, and the Stone Soul Picnic.

(Contact: Ms. Vicky Cahan, OCPL, Ph: 301-496-1752)

New Notices and Initiatives Relevant to the National Institute on Aging (NIA)

Excerpts from the NIH GUIDE - from April 16, 2005 to August 26, 2005

Includes Notices and Initiatives (Requests for Applications (RFAs) and Program Announcements (PAs), published since the May 2005 Council presentation of the Director's Status Report (DSR) to the National Advisory Council on Aging (NACA). Also check our NIA website for “Funding Opportunities”. *

(Shown here are selected Notices relevant to NIA /NIH/DHHS)

* Funding Opportunities

New Notices and Initiatives Relevant to the National Institute on Aging (NIA)

Excerpts from the NIH GUIDE - from April 16, 2005— August 26, 2005

Includes Notices and Initiatives (Requests for Applications (RFAs) and Program Announcements (PAs), published since the May 2005 Council presentation of the Director's Status Report (DSR) to the National Advisory Council on Aging (NACA). Also check our NIA website for “Funding Opportunities" at:

(Shown here are selected Notices relevant to NIA and selected Initiatives).

* Funding Opportunities

 

NOTICES ISSUED BY NIA
(Notices are sorted by release date. Most recent notices are at the end of this list.)

Notice

Issuing
Release Date
Expiration Date
Title
Number
Organization
NIA
8/24/2005
n/a

Notice Announcing Change in Funds Available for RFA-AG-06-001: The Claude D. Pepper Older Americans Independence Centers (OAICs)

NIA
8/11/2005
n/a
Request for Information on the Testosterone Formulations, Doses and Availability
NIA
8/10/2005
n/a
Clarification on Receipt Dates for PAR-05-148

NOTICES ISSUED BY OTHER INSTITUTES/CENTERS AT NIH (with NIA involvement)
(Notices are sorted by release date. Most recent notices are at the end of this list.)

Announcement Number
Issuing Organization
Release Date
Expiration Date
Title
NIMH
7/13/2005
n/a

Expiration of Human Brain Project (HBP) Program Announcements

NHGRI
5/31/2005
n/a

Extension of Bioengineering Nanotechnology Initiative (SBIR) Program Announcement (PA-02-125)

NIBIB
5/4/2005
n/a
Extension of Bioengineering Research Grant (BRG) Program Announcement (PA-02-011)
NIMH
4/28/2005
n/a
Correction to PAR-05-055: Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences
NOTICES ISSUED BY NIH (Central)
(Notices are sorted by release date. Most recent notices are at the end of this list.)
NIH
8/24/2005
n/a
October SCAW Advanced IACUC Workshop in Chicago, Illinois
NIH
8/24/2005
n/a
Conference, “Minimizing the Challenges Associated with an Academic IACUC Program” in Pennsylvania in October-November
NIH
8/23/2005
n/a
NIH Offers Commercialization Assistance Program to SBIR Phase II Awardees
NIH
8/19/2005
n/a
Security and Privacy Issues for Reviewer Registration with CCR
NIH
8/19/2005
n/a
NIH Announces Initial Plans to Transition to the SF424(R&R) Application and Electronic Submission through Grants.gov
NIH
8/19/2005
n/a
Small Business Innovation Research Program and Small Business Technology Transfer Research Program Electronic Registration
NIH
8/8/2005
n/a
Notice of Intent to Publish Four Requests for Applications (RFAs) for Knockout Mouse Project (KOMP)-This Notice announces the NIH's intention to issue three Requests for Applications (RFAs) in the late summer of 2005 for the Knockout Mouse Project (KOMP). A fourth RFA, for repositories for the resources generated by the other RFAs, will be published in the Fall 2005.
NIH
8/5/2005
n/a
New Process for Reimbursement of NIH Peer Reviewers-A new system will be implemented to reimburse reviewers who participate in NIH peer review meetings that take place after September 30, 2005 . This new system will ensure that expenses incurred while serving as a peer reviewer will be reimbursed at a comparable level to what is now reimbursed. Reviewers will no longer be required to submit vouchers and receipts for standard expenses.
NIH
8/4/2005
n/a
Small Business Innovation Research Program Contract Solicitation
NIH
8/4/2005
n/a
Guidelines for Inclusion of Clinical Practice Compensation in Institutional Base Salary Charged to NIH Grants and Contracts
NIH
8/2/2005
n/a
November 6 IACUC 101 Training to be held in St. Louis , Missouri
NIH
8/2/2005
n/a
Notice of Change for Fiscal Year 2006 Competing Applications for Ruth L. Kirschstein National Research Service Award (NRSA) T32 Institutional Training Grant Support
NIH
8/1/2005
n/a
Extramural Pediatric Research Loan Repayment Program
NIH
8/1/2005
n/a
Extramural Loan Repayment Program for Clinical Researchers
NIH
7/29/2005
n/a
Request for Information on the Plan to Recognize Multiple Principal Investigators on NIH Grants
NIH
7/15/2005
n/a
Announcing Locations for 2006 NIH Regional Seminars in Program Funding and Grants Administration
NIH
6/17/2005
n/a
Use of Current PHS 416-1 and PHS 416-9 Individual National Research Service Award (NRSA) Applications and Related Forms (OMB NO. 0925-0002)
NIH
6/17/2005
n/a
NIH Announces New Closeout Feature in the eRA Commons and Reminds Grantees of Required Closeout Reports for NIH Assistance Awards
NIH
5/3/2005
n/a
Extension of Expiration Dates for Various Ruth L. Kirschstein National Research Service Award Training and NIH Career Development Program Announcements and Notices
NIH
4/29/2005
n/a
Registration Open For Final 2005 NIH Regional Seminar In Program Funding And Grants Administration
NIH
4/29/2005
n/a
Implementation of Policy on Enhancing Public Access to Archived Publications Resulting from NIH-Funded Research
NIH
4/29/2005
n/a
Notice of Change in Number of Revisions of Small Grant Applications (R03)

 

FUNDING OPPORTUNITIES - RFAs and PAs - issued by NIA
(Opportunities are sorted by release date. Most recent items are at the end of this list.)

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
1
NIA
8/25/2005
11/24/2005
K23
Paul B. Beeson Career Development Awards in Aging

This program provides three to five years of mentored career development support to clinically-trained faculty members in strong research environments to enable them to gain skills and experience in aging research, under the guidance of a mentor or mentors, and to establish an independent program of research in this field.

Scientific/Research Contact:
Dr. Robin A. Barr
Office of Extramural Affairs
National Institute on Aging
Email: BarrR@mail.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
2
NIA
8/18/2005
9/2/2008

R01, R21

The Secretory Pattern of Senescent Cells The Secretory Pattern of Senescent Cells

This PA encourages applications that examine the changes in microenvironment that are induced by cell senescence, both in vivo and in vitro, and as a result of senescence being attained by any of the known inducers of this process.

Scientific/Research Contact:
Felipe Sierra, Ph.D.
Biology of Aging Program
National Institute on Aging
Email: sierraf@nia.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
3
NIA
8/12/2005
1/21/2006
R01, R21, R34
Anemia in the Elderly

The goal of this program is to foster biomedical research leading to a better understanding of the epidemiology, pathophysiology, and clinical aspects of anemia in the elderly.

Scientific/Research Contact:
Susan G. Nayfield, M.D., M.Sc.
Geriatrics and Clinical Gerontology Program
National Institute on Aging
Email: nayfiels@mail.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
4
NIA
8/3/2005
3/2/2008
U01
Alzheimer's Disease Drug Development Program

The objective of this solicitation is to stimulate research in the pre-clinical development and testing of novel therapeutic compounds aimed at slowing, halting, or reversing the progressive decline in cognitive function and modifying the behavioral symptoms in Alzheimer's disease (AD); or delaying the onset of or preventing AD, mild cognitive impairment (MCI), or age-related cognitive decline.

Scientific/Research Contact:
Neil S. Buckholtz, Ph.D.
Neuroscience and Neuropsychology of Aging Program
National Institute on Aging
Email: Bucknoln@nia.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
5
NIA
8/3/2005
10/26/2005
P30
Claude D. Pepper Older Americans Independence Centers (OAICs)

The Claude D. Pepper Older American Independence Centers (OAIC) program was established in honor of the late Representative to establish “centers of excellence” in geriatrics research and training. The goal of the OAIC program is to increase scientific knowledge that will lead to better ways to maintain or restore independence in older persons.

Scientific/Research Contact:
Susan G. Nayfield, M.D., M.Sc.
Geriatrics and Clinical Gerontology Program
National Institute on Aging
Email: nayfiels@mail.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
6
NIA
7/13/2005
9/2/2008
R01, R21
Testing Stem Cell Therapy in Mouse Models of Premature Aging

This PA encourages applications that test stem cell therapy in mouse models of accelerated aging, defined as mouse strains in which a genetic or other manipulation results in a shortened lifespan, and an accelerated appearance of a significant subset of age-related pathologies. The purpose is to use these models of accelerated aging to test whether stem cells extend the lifespan and/or reduce age-related pathology.

Scientific/Research Contact:
Felipe Sierra, Ph.D.
Biology of Aging Program
National Institute on Aging
Email: sierraf@nia.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
7
NIA
6/27/2005
4/2/2008
R41, R42, R43, R44
Applications of Imaging and Sensor Technologies for Clinical Aging Research (SBIR/STTR)

This initiative invites applications for the development and validation of new or improved imaging and sensor technologies that will enhance opportunities to address key research questions about human aging.

Scientific/Research Contact:
For scientific questions please contact:
Winifred K. Rossi, MA
Geriatrics and Clinical Gerontology Program
National Institute on Aging
Email: winnie_rossi@nih.gov
or
For questions regarding the SBIR/STTR Program please contact:
Michael-David Alphonsus Rodriguez Richardson Kerns, M.B.A., M.S., Ph.D.
Office of Extramural Affairs
National Institute on Aging
Email: kernsmd@mail.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
8
NIA
6/8/2005
9/15/2005
R01, R21
Inflammation, Inflammatory Mediators and Aging

This RFA seeks studies to determine relationships of age-related changes in inflammation and inflammatory mediators to physiologic and pathophysiologic aging changes, risks and progression of age-related morbidity and disability, and changes in tissue and organ function.

National Institute on Aging-Scientific/Research Contacts:
Sherry Sherman, Ph.D.
Geriatrics and Clinical Gerontology Program
Email: shermans@nia.nih.gov
or
Jill Carrington, Ph.D.
Biology of Aging Program
Email: carringj@nia.nih.gov
or

Andrew Monjan, Ph.D.
Neuroscience and Neuropsychology of Aging Program
Email: monjana@mail.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
9
NIA
4/21/2005
9/21/2005
P30
Alzheimer's Disease Core Centers

This initiative invites applications from qualified institutions for support of Alzheimer's Disease Core Centers (ADCCs). These Centers are designed to serve as shared research resources that will facilitate research on Alzheimer's disease (AD) and related disorders, distinguish them from the process of normal brain aging and mild cognitive impairment (MCI), and lead to better diagnostic and treatment strategies.

Scientific/Research Contact:
Creighton H. Phelps, Ph.D.
Neuroscience and Neuropsychology of Aging Program
National Institute on Aging
Email: phelpsc@nia.nih

FUNDING OPPORTUNITIES - Other RFAs and PAs with NIA involvement, but issued by NIH (central) or other Institutes at NIH
(Notices are sorted by release date. Most recent notices are at the top of this list.)

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
1
NBNR
8/19/2005
10/26/2005
R01, R21
New Ways to Image Neural Activity

This RFA is an initiative of the NIH Blueprint for Neuroscience Research (http://neuroscienceblueprint.nih.gov), a coordinated effort of 15 NIH Institutes and Centers to accelerate progress in neuroscience by supporting research and development of enabling tools and resources. This RFA will be administered by the NIBIB on behalf of the Neuroscience Blueprint.

Scientific/Research Contact:
Molly Wagster, Ph.D.
Neuroscience and Neuropsychology of Aging Program
National Institute on Aging
Email: wagsterm@nia.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
2
NIH
8/8/2005
9/2/2008

F30

Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral MD/PhD Fellows (F30)

Several Institutes/Centers at NIH including NIA are interested in supporting individual predoctoral fellowships for combined MD/PhD training in research areas relevant to the mission of the participating Institutes. Integrated curricula that combine training for the MD degree with extensive research experience have been developed because scientists who are both medical doctors and trained scientists play a vital role in helping to bring the highest scientific standards into basic, clinical, translational, epidemiologic, prevention, and services research settings.

Scientific/Research Contact:
Dr. Robin Barr
Office of Extramural Affairs
National Institute on Aging
Email: BarrR@mail.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
3
NIH
7/22/2005
9/2/2008

K23

Mentored Patient-Oriented Research Career Development Award (K23)

The purpose of the Mentored Patient-Oriented Research (POR) Career Development Award (K23) is to support the career development of investigators who have made a commitment to focus their research endeavors on patient-oriented research.

Scientific/Research Contact:
Dr. Robin A. Barr
Office of Extramural Affairs
National Institute on Aging
Email: BarrR@mail.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title

4

NICHD
7/6/2005
9/2/2008

R25

Educational Programs for Population Research

This announcement provides a mechanism to support specialized educational needs within population research. Meeting these needs will advance population research by enhancing the development of interdisciplinary scientists and facilitating interdisciplinary studies, improving the dissemination and use of existing data sets in population research, and advancing the adoption of quantitative and qualitative methodologies.

Scientific/Research Contact:
John G. Haaga, Ph.D.
Behavioral and Social Research Program
National Institute on Aging
Email: HaagaJ@mail.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
5
NIH
6/30/2005
9/9/2005

T15

Short-Term Courses In Human Embryonic Stem Cell Culture Techniques

The objective of this grant program is to support the development, implementation and evaluation of short-term continuing education programs on skills and techniques in human embryonic stem cell research, and the dissemination of course materials and programmatic instructional experience to the larger scientific community.

Scientific/Research Contact:
Jill L. Carrington, Ph.D.
Chief, Systems Branch, Director, Musculoskeletal Biology
Biology of Aging Program
National Institute on Aging
E-mail: CarringtonJ@nia.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
6
NIMH
6/14/2005
4/2/2008

R01, R21

Development of PET and SPECT Ligands for Brain Imaging (SBIR/STTR AWARD)

This initiative is intended to stimulate the development of radioligands for molecular targets (e.g., receptors, cell adhesion molecules, intracellular messengers, and disease related proteins) that are of broad interest to the scientific community.

Scientific/Research Contact:
Susan Molchan, M.D.
Program Director, Alzheimer's Disease Clinical Trials
Neuroscience and Neuropsychology of Aging Program
National Institute on Aging
Email: molchans@mail.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
7
NIMH
6/13/2005
4/2/2008
R41, R42, R43, R44
Probes for Microimaging The Nervous System (SBIR/STTR AWARD)

This initiative program encourages grant applications that propose research and development of probes useful in imaging the structure and function of the brain and other parts of the nervous system, with award duration and amounts greater than those routinely allowed under the SBIR/STTR programs.

Scientific/Research Contact:
D. Stephen Snyder, Ph.D.
Neuroscience and Neuropsychology of Aging
National Institute on Aging
Email: ss82f@nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
8
NIH
6/32005
9/2/2008
T35
Ruth L. Kirschstein National Research Service Award Short-Term Institutional Research Training Grants (T35)

The T35 program provides short-term support for training experiences under the supervision of experienced researchers and exposes students to individuals with active research careers as well as providing them with knowledge about further research training and biomedical or behavioral research career opportunities.

Scientific/Research Contact:
Dr. Robin A. Barr
Office of Extramural Affairs
National Institute on Aging
Email: BarrR@nia.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
9
NIDDK
5/6/2005
7/2/2008
R01, R21
Pilot and Feasibility Program Related to the Kidney

This initiative encourages investigator-initiated high-risk pilot and feasibility research by newly independent or established investigators, to develop new ideas sufficiently to allow for subsequent submission of R01 applications focusing on research problems relevant to the study of both acute and chronic kidney diseases, and their complications, in both the adult and pediatric populations.

Scientific/Research Contact:
Frank Bellino, PhD
Biology of Aging Program
National Institute on Aging
Email: fb12a@nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
10
FIC
5/3/2005
8/24/2007
R01, R21
Brain Disorders in the Developing World: Research Across the Lifespan

The purpose of the Brain Disorders in the Developing World: Research Across the Lifespan PA is to support the development and conduct of innovative, collaborative research and research training projects, between developed and developing country scientists, on brain disorders throughout life, relevant to low- and middle-income nations.
Scientific/Research Contact:

Andrew A. Monjan, Ph.D., M.P.H.
Chief, Neurobiology of Aging Branch
Neuroscience and Neuropsychology of Aging Program
National Institute on Aging
Email: monjana@nia.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
11
NINDS
4/26/2005
7/2/2008
R01, R03, R21
Mechanisms of Transmission and Dissemination of Transmissible Spongiform Encephalopathies (TSEs)

This initiative encourages investigator-initiated research grant applications to study the mechanisms of transmission and dissemination of transmissible spongiform encephalopathies (TSEs).

Scientific/Research Contact:
Andrew A. Monjan, Ph.D.
Chief, Neurobiology of Aging Branch
Neuroscience and Neurophysiology of Aging
National Institute on Aging
Email: am39m@nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
12
NINDS
4/25/2005
7/2/2008
R01, R21
Collaborative Awards in Epilepsy Research for Junior Investigators

This initiative encourages those interested in promoting collaborations among junior investigators (Postdoctoral trained researchers with institutional appointments through Assistant Professors, or equivalent) to stimulate research in the field of epilepsy.

Scientific/Research Contact:
Bradley C. Wise
Neuroscience and Neuropsychology of Aging Program
National Institute on Aging
Email : wiseb@nia.nih.gov

Number

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
13
NINDS
4/21/2005
5/2/2008
R01, R03, R21
Interactions Between Stem and Progenitor Cells and the Microenvironment In Vivo

The objective of this initiative is to promote a thorough exploration and characterization of the bi-directional communication between multipotent cells and the three-dimensional local milieu or niche that they encounter in vivo under normal and compromised states, such as with aging or following injury, disease or drug exposure.

Scientific/Research Contact:
Bradley C. Wise, Ph.D.
Neuroscience and Neuropsychology of Aging Program
National Institute on Aging
E-mail: wiseb@nia.nih.gov

NIH Roadmap Initiatives

NIH Roadmap Initiatives have been planned to help enable NIH to sustain its historic record of cutting-edge contributions that are central to extending the quality of healthy life for people in this country and around the world. All NIH Institutes and Centers participate in Roadmap initiatives. Below is a list of Roadmap initiatives released since the last presentation of the Director's Status Report (DSR) at the May 2005 council meeting. Releases are sorted with the most recent ones at the end of the list. (For more information visit the NIH Roadmap Initiatives website.)

Announcement Number

Issuing Organization
Release Date
Expiration Date
Activity Code(s)
Title
Roadmap
7/9/2005
5/19/2006
X01
Solicitation of Assays for High Throughput Screening (HTS) in the Molecular Libraries Screening Centers Network (MLSCN)
The goal of the MLSCN is to empower the research community to use small molecule compounds in their research, whether as tools to modulate genes and pathways, as imaging probes in basic or clinical applications, or as starting points for the development of new therapeutics for human disease. The MLSCN will be the engine of discovery in the NIH Roadmap Molecular Libraries initiative.

Budget Table

NIA Mechanism Table—September 2005 Director's Status Report
(Dollars in Thousands)

Includes Aids

2004
Actual

2005
Appropriation

%chg
of $$$
2006 Est
%chg
of $$$
Incr/Decr
No.
Amount
No.
Amount
No.
Amount
No.
Amount
Res. Proj. Grants
Noncompeting
973
$500,991
1,090
$541,578
8.1%
1,032
$526,623
-2.8%
(58)
($14,955)
Competing
419
166,194
349
139,520
-16.0%
390
156,132
11.9%
41
16,612
Subtotal, Res. Proj.
1,392
667,185
1,439
681,098
2.1%
1,422
682,755
0.2%
(17)
1,657
SBIR/STTR
87
24,535
87
24,927
1.6%
87
24,927
0.0%
0
0
Total, Res. Proj.
1,479
691,720
1,526
706,025
2.1%
1,509
707,682
0.2%
(17)
1,657
Research Centers
77
83,758
76
86,615
3.4%
77
87,712
1.3%
1
1,097
Other Research
Research Careers
194
25,213
204
25,601
1.5%
206
26,017
1.6%
2
416
Other
32
6,993
30
6,608
-5.5%
30
6,784
2.7%
0
176
Total, Other
226
32,206
234
32,209
0.0%
236
32,801
1.8%
2
592
Total, Res. Grants
1,782
807,684
1,836
824,849
2.1%
1,822
828,195
0.4%
(14)
3,346
Research Training
Individual
62
2,610
62
2,717
4.1%
61
2,717
0.0%
(1)
0
Institutional
488
21,132
481
21,666
2.5%
480
21,666
0.0%
(1)
0
Total, Training
550
23,742
543
24,383
2.7%
541
24,383
0.0%
(2)
0
R&D Contracts
132
56,797
132
61,576
8.4%
133
62,197
1.0%
1
621
Intramural Res.
99,962
103,491
3.5%
104,548
1.0%
1,057
Res. Mgt. & Support
36,413
37,691
3.5%
37,880
0.5%
189
Total, NIA
1,024,598
1,051,990
2.7%
1,057,203
0.5%
5,213

Page last updated Sep 26, 2008