[TTT Membership Roster] [TTT Meeting Rosters]
The Transplantation, Tolerance and Tumor Immunology (TTT) Study Section reviews applications involving the making and breaking of immune tolerance. This includes human and animal studies of immune-mediated transplant rejection, basic mechanisms of acquired immune tolerance, and studies of tumor immunology and vaccine development. Emphasis is on immune mechanisms. Specific areas covered by TTT:
- Transplantation: studies of transplant rejection when the major focus is on the immune response to the transplanted organ and immune mechanisms behind immunosuppressive drugs and therapies for prevention of transplant rejection; solid organ and hematopoietic transplant tolerance, in both small and large animal models as well as clinical studies and clinical trials; mechanisms of development and strategies for prevention of graft vs. host disease, including promotion of graft vs. tumor/leukemia effects.
- Tolerance: mechanisms of immune tolerance, both central and peripheral, using a variety of systems including engineered mice and tumor, autoimmune, or transplant models.
- Tumor Immunology: immune surveillance, mechanisms of immune evasion, or immune suppression in the tumor microenvironment, in both humans and animal models; identification of new tumor associated antigens; early stage development and testing of tumor vaccines in animal models.
Study sections with the most closely related areas of science listed in rank order are:
Cancer Immunopathology and Immunotherapy (CII)
Hypersensitivity, Autoimmune, and Immune-Mediated Diseases (HAI)
Cellular and Molecular Immunology A (CMIA)
Cellular and Molecular Immunology B (CMIB)
Innate Immunity and Inflammation (III)