Clinical Trials
HIV/AIDS
Featured Studies
Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
The Use of a Distress Thermometer in a Pediatric Research Setting: An Exploratory, Pilot Study.
Evaluation study. PRECIS: OBJECTIVE: The purpose of this protocol is to evaluate a measure that would assist clinicians in assessing the presence of psychological distress in children and adolescents with serious medical illnesses. Ages 7-21. Location in Bethesda, MD.
- HIV Prevention and Trauma Treatment in Men Who Have Sex With Men and Who Have a History of Sexual Abuse.
Interventional study. This study will develop a therapy for men who have sex with men who also have a history of childhood sexual abuse to reduce behaviors that put them at a high risk of HIV infection. Ages 18 and over. Location in Boston, MA.
- Effectiveness of Armodafinil for Treating Fatigue in Adults With HIV/AIDS.
Interventional study. This study will determine whether armodafinil (Nuvigil), an FDA approved medication, is effective in reducing fatigue in adults with HIV/AIDS. Ages 18-70. Location in New York, NY.
- Effectiveness of Community-Level Behavioral and Biomedical Interventions for Reducing HIV/STIs in Men in Peru.
Interventional study. This study will evaluate the effectiveness of community-level behavioral and biomedical interventions, each alone and combined, in reducing sexual risk behavior and HIV/sexually transmitted infections in Peruvian men who have sex with men. Ages 18-45. Location in Lima, Peru.
- Adult Sexual Risk Behavior Among Women With a History of Childhood Sexual Abuse.
Evaluation study. This study will evaluate whether childhood experiences are related to current sexual behavior of adult women. Ages 18 and over. Location in Rochester, NY.
- Providing Voluntary HIV Counseling and Testing Plus Linkage to Care in Uganda.
Interventional study. This study will compare the effectiveness of brief versus detailed HIV counseling sessions, paired with referrals to either HIV-specific medical care or usual care, in reducing HIV risk behavior and in increasing treatment adherence in Uganda. Ages 18 and over. Location in Kampala, Uganda.
- Effectiveness of HIV/Sexually Transmitted Infection Training for Physicians in China.
Interventional study. This study will evaluate the effectiveness of a physician training program, the Ai Shi Zi program, in improving HIV/sexually transmitted infection diagnosis, treatment, and management by Chinese physicians and in reducing the number of subsequent infections in their patients. Ages 18-45. Location in Hefei, China.
- Effectiveness of Integrating Prenatal Care in Reducing HIV/STDs Among Young Pregnant Women.
Interventional study. This study will evaluate the effectiveness of CenteringPregnancy Plus, a group prenatal care treatment program with an HIV/sexually transmitted disease prevention component, in reducing health risk behaviors in pregnant teenagers seeking services at Community Health Centers in the New York metropolitan area. Ages 14-21. Locations in Cheshire, CT; New Haven, CT; New York, NY.
- An Educational and Supportive Counseling Program for Increasing Antiretroviral Use and Adherence in People With HIV.
Interventional study. This study will develop and test the effectiveness of an educational and supportive counseling program called Preparing Patients to Start Antiretroviral Therapy in helping people with HIV make informed decisions about their health care. Ages 18 and over. Location in San Francisco, CA.
- Antidepressant Medication and Cognitive Behavioral Therapy to Help HIV Infected Adults With Depression to Adhere to Antiretroviral Therapy.
Interventional study. This study will compare the effectiveness of antidepressant therapy alone versus antidepressant therapy combined with cognitive behavioral therapy in helping HIV infected adults with depression to take their medications on schedule. Ages 18-60. Location in Torrance, CA.
- Two Approaches to Routine HIV Testing in a Hospital Emergency Department.
Interventional study. This study will compare the effectiveness of two different approaches to providing routine HIV counseling, testing, and referral services in an urban hospital emergency department setting. Ages 18 and over. Location in Boston, MA.
- Effects of HIV and Hepatitis C Virus on the Brain.
Evaluation study. This study will determine the effects that HIV and hepatitis C virus have on thinking abilities and whether the viruses affect brain chemistry. Ages 18-65. Location in New York, NY.
- Assisting HIV-Infected Mothers in Disclosing Their Serostatus to Their Children.
Interventional study. This study will develop and evaluate the effectiveness of an intervention designed to assist HIV-infected mothers of young children in determining whether and how to appropriately disclose their HIV serostatus to their children. Ages 6-65. Location in Los Angeles, CA.
- Effectiveness of a Telephone-Delivered Behavioral Treatment to Improve the Quality of Life of Older Adults With HIV.
Interventional study. This study will evaluate the effectiveness of a telephone-delivered coping improvement group intervention in improving quality of life in older adults with HIV. Ages 50 and over. Location in Athens, OH.
- STD Risk Reduction for Heterosexual Methamphetamine Users.
Interventional study. This study will evaluate the effectiveness of a sexual risk reduction intervention in reducing sexual risk behavior in HIV uninfected, heterosexual people who use methamphetamine. Ages 18 and over. Location in San Diego, CA.
- Effectiveness of Structured Ecosystems Therapy for Reducing HIV Risk Behaviors and Improving Treatment Adherence in HIV Infected Men Released From Prison.
Interventional study. This study will evaluate the effectiveness of Structured Ecosystems Therapy (SET), a form of therapy that includes family and caregivers, at reducing HIV transmission risk behaviors and improving treatment adherence in HIV infected men newly released from prison. Ages 18 and over. Location in San Francisco, CA.
- Antidepressant Medication Plus Directly Observed Therapy for Improving Adherence to Antiretroviral Therapy.
Interventional study. This study will evaluate the effectiveness of directly observed therapy plus antidepressant medication in improving adherence to antiretroviral drug therapy among HIV-infected homeless and marginally housed people with depression. Ages 18 and over. Location in San Francisco, CA.
- Share Safer Sex Counseling Program for Changing Sexual Risk Behaviors in Mexican Female Sex Workers.
Interventional study. This study will evaluate the effectiveness of the Share Safer Sex Program in reducing sexual risk behaviors among female sex workers in four Mexican cities close to the U.S. Ages 18 and over. Location in Tijuana, Mexico.
- Modified Directly Observed Therapy for Improving Antiretroviral Therapy Adherence in People With HIV.
Interventional study. This study will evaluate the effectiveness of a modified directly observed therapy program in increasing antiretroviral therapy adherence in poor, HIV-infected residents of urban communities. Ages 18 and over. Location in San Francisco, CA.
- Specialized Cognitive-Behavioral Counseling Intervention to Reduce HIV Transmission Risk Behavior in HIV-Infected Men.
Interventional study. This study will evaluate the effectiveness of a specialized cognitive-behavioral counseling intervention in reducing sexual risk behaviors in men who are HIV-infected and report having unprotected sex with male partners who are either not HIV-infected or do not know if they are HIV-infected. Ages 18 and over. Location in San Francisco, CA.
- A Peer-Oriented HIV Prevention Outreach Program for Individuals at High Risk for HIV and Other Sexually Transmitted Diseases.
Interventional study. This study will determine the effectiveness of a peer outreach intervention in preventing HIV infection in adults at high risk for contracting HIV and other sexually transmitted diseases (STDs). Ages 18 and over. Location in Baltimore, MD.
- Community Mobilization, Mobile Testing, Same-Day Results, and Post-Test Support for HIV in Sub-Saharan Africa and Thailand.
Interventional study. This study will evaluate the effectiveness of a combination of clinic- and community-based voluntary counseling and testing programs in preventing HIV in African and Thai communities. Ages 16 and over. Locations in Chiang Mai, Thailand; Dar es Salaam, Tanzania; Harare, Zimbabwe; Pietermaritzburg, South Africa; Soweto, Johannesburg, South Africa.
- Managed Problem Solving to Increase Treatment Adherence in Individuals With HIV.
Interventional study. This study will determine whether a managed problem solving intervention can help patients with HIV better follow their anti-HIV drug regimen and can control HIV better than the standard of care. Ages 18 and over. Location in Philadelphia, PA.
Search ClinicalTrials.gov for other NIH studies on HIV/AIDS.
