Summaries & Associations of Study Results
TR-300 3-Chloro-2-Methylpropene
Target Organs and Levels of Evidence
NTP Technical Report Number 300
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| 3-CHLORO-2-METHYLPROPENE 563-47-3 |
11/02/84 | FUMIGANT. INSECTICIDE. INTERMEDIATE IN PRODUCTION OF PLASTICS, PHARMACEUTICALS, HERBICIDES & PESTICIDES. (TDB) | Gavage R: 0,75,150, M: 0,100,200 MG/KG/50 PER GROUP | Litton Bionetics, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: CLEAR EVIDENCE | FORESTOMACH: SQUAMOUS CELL PAPILLOMA 1/50 5/50 30/48; SQUAMOUS CELL CARCINOMA 0/50 0/50 2/48 | |||
| FR: CLEAR EVIDENCE | FORESTOMACH: SQUAMOUS CELL PAPILLOMA 1/50 1/50 10/50 | |||
| MM: CLEAR EVIDENCE | FORESTOMACH: SQUAMOUS CELL PAPILLOMA 3/49 19/49 30/49; SQUAMOUS CELL CARCINOMA 0/49 5/49 7/49 | |||
| FM: CLEAR EVIDENCE | FORESTOMACH: SQUAMOUS CELL PAPILLOMA 0/50 15/48 29/44; SQUAMOUS CELL CARCINOMA 0/50 1/48 2/44 | |||
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