Cell Biology |
Neuroscience & Degenerative Diseases |
Cancer & Oncological Sciences |
Karbowski, M., Arnoult, D., Chen, H., Chan D.C., Smith, C., and Youle, R.J.. Quantification of mitochondrial dynamics by photolabeling of individual organelles shows mitochondrial fusion is blocked during apoptosis upstream of Bax/Bak mediated caspase activation. J. Cell Biol.164:493-499, 2004. Commentary in J. Cell Biol.
Jeong, S-Y., Gaume, B., Lee, Y.J., Hsu, Y.T., Ryu, S.W., Yoon, S.H. and Youle, R.J. Bcl-XL sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers. EMBO J. 23:2146-2155, 2004.
Arnoult, D., Bartle, L.M., Skaletskaya, A., Zamzami, N., Poncet, D., Park, P., Sharpe, J., Youle, R.J., Goldmacher, V.S. Cytomegalovirus cell death suppressor vMIA interacts with Bax and blocks Bax-mediated apoptosis, but fails to suppress Bak-mediated apoptosis. Proc. Natl. Acad. Sci. USA 101:7988-7993, 2004.
Karbowski, M., Jeong, S-Y. and Youle R.J. Endophilin B1 participates in the mitochondrial division machinery. J. Cell Biol.166: 1027-1039, 2004.
Lee, Y.J., Jeong, S.J., Karbowski, M., Smith, C.L. and Youle R. J. Roles of the mitochondrial fission and fusion mediators, Fis1, Drp1 and Opa1, in apoptosis. Mol. Biol. Cell in press, 2004.