Carmen J. Williams, M.D., Ph.D.
Tel (919) 541-2158
Fax (919) 541-0696
P.O. Box 12233
Mail Drop E4-05
Research Triangle Park, North Carolina 27709
The Reproductive Medicine Group examines the molecular basis of early reproductive events including gamete maturation and function, fertilization, and implantation. For many of these studies, the mouse model system is used because it closely approximates early reproductive processes in the human. For some studies group members are able to use human tissues or gametes to learn directly about human reproduction and human diseases, such as endometriosis, that affect health and fertility. The overall goal of this work is to improve understanding of the basic processes involved in regulating early reproduction and development, and thereby provide a rational scientific basis for improving both human reproductive health and contraceptive options. There is increasing interest in the idea that environmental toxins/endocrine disruptors significantly affect human fertility. The Reproductive Medicine Group will pursue how these agents affect early reproductive events in normal couples and in those with infertility.
Major areas of research: