National Toxicology Program

(CAS# 59865-13-3)

• Primary Uses or Exposures: Cyclosporin A is used as an immunosuppressive agent in the prevention and treatment of graft-vs-host reactions in bone marrow transplantation, and for the prevention of rejection of kidney, heart, and liver transplants.
• Nominated by: NIEHS
• Basis for Nomination: IARC¹ classification as carcinogenic to humans based on sufficient evidence in humans
• Current Status: Listed in the RoC as known to be a human carcinogen since the 8th RoC (1998)

¹ International Agency For Research On Cancer (IARC)