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Sponsored by: |
Abbott Vascular |
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Information provided by: | Abbott Vascular |
ClinicalTrials.gov Identifier: | NCT00180466 |
PROSPECT is a multi-center prospective registry of Acute Coronary Syndromes (ACS) patients with single or double vessel coronary artery disease. Approximately 700 patients with ACS will be enrolled into the study at sites in the United States and European Union.
Condition |
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Coronary Disease Coronary Artery Disease Coronary Restenosis |
Study Type: | Observational |
Study Design: | Prospective |
Official Title: | Providing Regional Observations to Study Predictors of Events in the Coronary Tree (PROSPECT) An Imaging Study in Patients With Unstable Atherosclerotic Lesions |
Aproximately 1 ML blood
Enrollment: | 697 |
Study Start Date: | October 2004 |
Estimated Study Completion Date: | April 2011 |
To identify in patients presenting with ACS imaging modalities and/or serologic markers of inflammation which may aid in the identification of non-flow obstructing lesions with an increased risk for future acute coronary events. This study will ascertain the prevalence and clinical significance of non-flow obstructing lesions, which subsequently result in acute coronary events - defined as vulnerable plaque. The safety of regional imaging of non-culprit lesions in ACS patients will also be assessed.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Patients presenting with an Acute Coronary Syndrome that require catheterization and interventional treatment of a culprit lesion(s).
Inclusion Criteria:
Patient must have evidence of an ACS requiring catheterization documented by the presence of any one of the following conditions:
Key Clinical Exclusion Criteria:
Principal Investigator: | Gregg Stone, MD | Columbia University Medical Center |
Principal Investigator: | Patrick Serruys, MD, PhD | Thoraxcenter, Erasmus University, Rotterdam, The Netherlands |
Principal Investigator: | Bernard de Bruyne, MD | Cardiovascular Center, OLV Hospital, Aalst, Belgium |
Responsible Party: | Abbott Vascular ( Matt Kiely ) |
Study ID Numbers: | 04-800 |
Study First Received: | September 13, 2005 |
Last Updated: | October 29, 2008 |
ClinicalTrials.gov Identifier: | NCT00180466 |
Health Authority: | United States: Institutional Review Board |
drug eluting stents stents angioplasty coronary artery disease total coronary occlusion |
coronary artery restenosis stent thrombosis vascular disease myocardial ischemia coronary artery stenosis |
Arterial Occlusive Diseases Heart Diseases Myocardial Ischemia Vascular Diseases Constriction, Pathologic Ischemia Arteriosclerosis |
Coronary Restenosis Coronary Stenosis Thrombosis Coronary Disease Coronary Occlusion Coronary Artery Disease |
Cardiovascular Diseases |