CounterACT Publications 2009

CounterACT Publications

Neurotoxic Organophosphorus Poisons (e.g. anti-convulsants, anti-seizures, neuroprotectants, cholinesterase reactivators, nerve agent bioscavengers)

Albuquerque EX, Pereira, EF, Alkondon M, Rogers SW. (2009) Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol. Rev. 89(1): 73-120.  Abstract

Alkondon M, Aracava Y, Pereira ER, Albuquerque EX. (2009) A single in vivo application of cholinesterase inhibitors has neuron type-specific effects on nicotinic receptor activity in guinea pig hippocampus. J Pharmacol Exp Ther. 328(1): 69-82.  Abstract 

Fawcett WP, Aracava Y, Adler M, Pereira EF, Albuquerque EX. (2009) Acute toxicity of organophosphorus compounds in guinea pigs is sex and age dependent and cannot be solely accounted by acetycholinesterase inhibition. J Pharmacol Exp Ther. 328(2): 516-24.  Abstract

Li B, Schopfer LM, Grigoryan H, Thompson CM, Hinrichs SH, Masson P, Lockridge O. (2009) Tyrosines of human and mouse transferrin covalently labeled by organophosphorus agents: a new motif for binding to proteins that have no active site serine. Toxicol Sci 107(1): 144-55.  Abstract

Qashu F, Figueiredo TH, Aroniadou-Anderjaska V, Apland, JP, Braga MF. (2009) Diazepam administration after prolonged status epilepticus reduces neurodegeneration in the amygdala but not in the hippocampus during epileptogenesis.  Amino Acids [Epub ahead of print]  Abstract

 

---

Vesicating Agents (e.g. sulfur mustard)

Day BJ. (2008) Catalase and glutathione peroxidase mimics. Biochem Pharmacol. 77(3): 285-96. Abstract

Gerecke DR, Chen M, Isukapalli SS, Gordon MK, Chang YC, Tong W, Androulakis IP, Georgopoulos PG. (2009) Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect. Toxicol Appl Pharmacol. 234(2): 156-65.  Abstract

 

---

Pulmonary Agents (e.g. chlorine, bromine, etc.)

Bein K, Wesselkamper SC, Liu X, Dietsch M, Majumder N, Concel VJ, Medvedovic M, Sartor M, Henning LN, Venditto C, Borchers MT, Barchowsky A, Weaver TE, Tichelaar JW, Prows DR, Korfhagen TR, Hardie WD, Bachurski CJ, Leikauf GD. (2009) Surfactant associated protein B is critical to survival in nickel-induced injury in mice. Am J Respir Cell Mol Biol. [Epub ahead of print]  Abstract

Lazrak A, Nita I, Subramaniyam D, Wei S, Song W, Ji H, Janciauskiene S, Matalon S. (2009) Alpha1-antitrypsin inhibits epithelial Na+ transport in vitro and in vivo. Am J Respir Cell Mol Biol. [Epub ahead of print] Abstract

Matalon S, Shrestha K, Kirk M, Waldheuser S, McDonald B, Smith K, Gao Z, Belaaouaj A, Crouch EC. (2009) Modification of surfactant protein D by reactive oxygen-nitrogen intermediates is accompanied by loss of aggregating activity, in vitro and in vivo. FASEB J. [Epub ahead of print]  Abstract

Sartor MA, Leikauf GD, Medvedovic M. (2009) LRpath: A logistic regression approach for identifying enriched biological groups in gene expression data. Bioinformatics 25(2):211-7.  Abstract

Song W, Liu G, Bosworth CA, Walker JR, Megaw GA, Lazrak A, Abraham E, Sullender WM, Matalon S. (2009) Respiratory syncytial virus inhibits lung ENaC by upregulating iNOS. J Biol Chem. [Epub ahead of print]  Abstract

 

---

Metabolic/Cellular Toxins (e.g. cyanide)

 

---

Paralytic Neurotoxins (e.g. scorpion toxins)

 

---

Diagnostics (e.g. EEG devices, OP detectors/biosensors)

Barry RC, Lin Y, Wang J, Liu G, Timchalk CA. (2009) Nanotechnology-based electrochemical sensors for biomonitoring chemical exposures. J Expo Sci Environ Epidemiol. 19(1):1-18.  Abstract

 

---

(13 Total 2009 Publications)