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Topic: digestive diseases (dd)
Title: Frequency of Gallstones After Renal Transplantation and Factors That Affect Gallstone Formation: A Comparative Study.
Author: Celik, A.F.; et al.
Source: Dialysis and Transplantation. 36(10): 533-542, 555. October 2007.
Abstract: This article reports on a study of the frequency of gallstones in kidney transplant recipients, focusing on the effects of various factors on gallstone formation. The study included 182 patients who had undergone renal transplantation at the authors’ center in the last 12 years. Of these, 163 patients were followed up regularly; of these, 118 were using cyclosporine A (CsA). The median duration of patient follow-up was 36 months. All patients underwent abdominal ultrasonography and laboratory tests. Gallstones were diagnosed in five patients (3.1 percent). The frequency of gallstones was 3.4 percent in the CsA group and 2.2 percent in the non-CsA group. The CsA group had a significantly shorter gallstone-free follow-up period than the non-CsA group. The authors conclude that the use of CsA showed a trend toward increasing the risk of developing a gallstone sooner in the posttransplant period, particularly for young men. 1 figure. 4 tables. 24 references.

Format: Journal Article
Language: English.
Major Keywords: Kidney Diseases. Kidney. Transplantation. Gallstones. Immunosuppressive Agents. Risk Factors. Etiology.
Minor Keywords: Cyclosporine. Epidemiology. Incidence. Drug Therapy. Drug Effects. Age Factors. Postoperative Complications.
Publication Number: DDJA13047
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