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Topic: digestive diseases (dd)
Title: Catheter-Related Complications of Total Parenteral Nutrition.
Author: Buchman, A.L.
Source: American Journal of Gastroenterology. 102: S97-S101. 2007.
Abstract: This article describes the hepatobiliary complications that can occur with the use of total parenteral nutrition (TPN). The author reviews the background and incidence of TPN-associated liver disease; the risk factors associated with the development of TPN-associated liver disease; potential etiologies of TPN-associated liver disease including malnutrition, overnutrition, carnitine deficiency, choline deficiency, bacterial overgrowth, and methionine toxicity; and treatment options including medical treatment and nutritional treatment. Patients can only prevent hepatobiliary complications, including hepatic steatohepatitis, cirrhosis, and liver failure, if they eat. Eating allows the patient to preserve as much portal nutrient absorption as possible. A final section considers the problem of TPN-associated biliary disease, notably biliary tract stones and gallstones. 5 figures. 53 references.

Format: Journal Article
Language: English.
Major Keywords: Digestive System Diseases. Patient Care Management. Complications. Parenteral Nutrition. Liver Diseases. Biliary Tract Diseases.
Minor Keywords: Malnutrition. Hepatitis. Fatty Liver. Gallstones. Biliary Tract Stones. Liver Disease. Drug Therapy. Cirrhosis.
Publication Number: DDJA12932.
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