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Volume 4;  2007
Commentaries
Can visco-elastic phase separation, macromolecular crowding and colloidal physics explain nuclear organisation?
Francisco J Iborra
Theor Biol Med Model. 2007; 4: 15. Published online 2007 April 12. doi: 10.1186/1742-4682-4-15.
PMCID: PMC1853075
Lens stem cells may reside outside the lens capsule: an hypothesis
Susann G Remington and Rita A Meyer
Theor Biol Med Model. 2007; 4: 22. Published online 2007 June 8. doi: 10.1186/1742-4682-4-22.
PMCID: PMC1914343
Research
A stochastic model for circadian rhythms from coupled ultradian oscillators
Roderick Edwards, Richard Gibson, Reinhard Illner, and Verner Paetkau
Theor Biol Med Model. 2007; 4: 1. Published online 2007 January 9. doi: 10.1186/1742-4682-4-1.
PMCID: PMC1794229
Directed cell migration in the presence of obstacles
Ramon Grima
Theor Biol Med Model. 2007; 4: 2. Published online 2007 January 16. doi: 10.1186/1742-4682-4-2.
PMCID: PMC1797164
Bayesian profiling of molecular signatures to predict event times
Dabao Zhang and Min Zhang
Theor Biol Med Model. 2007; 4: 3. Published online 2007 January 19. doi: 10.1186/1742-4682-4-3.
PMCID: PMC1796541
Morphological instability and cancer invasion: a 'splashing water drop' analogy
Caterina Guiot, Pier P Delsanto, and Thomas S Deisboeck
Theor Biol Med Model. 2007; 4: 4. Published online 2007 January 25. doi: 10.1186/1742-4682-4-4.
PMCID: PMC1794228
A computational model for functional mapping of genes that regulate intra-cellular circadian rhythms
Tian Liu, Xueli Liu, Yunmei Chen, and Rongling Wu
Theor Biol Med Model. 2007; 4: 5. Published online 2007 January 30. doi: 10.1186/1742-4682-4-5.
PMCID: PMC1803780
Relating a calcium indicator signal to the unperturbed calcium concentration time-course
Alexander Borst and Henry DI Abarbanel
Theor Biol Med Model. 2007; 4: 7. Published online 2007 February 6. doi: 10.1186/1742-4682-4-7.
PMCID: PMC1800305
Inclusion of the glucocorticoid receptor in a hypothalamic pituitary adrenal axis model reveals bistability
Shakti Gupta, Eric Aslakson, Brian M Gurbaxani, and Suzanne D Vernon
Theor Biol Med Model. 2007; 4: 8. Published online 2007 February 14. doi: 10.1186/1742-4682-4-8.
PMCID: PMC1804264
Biological effects of deuteronation: ATP synthase as an example
Abdullah Olgun
Theor Biol Med Model. 2007; 4: 9. Published online 2007 February 22. doi: 10.1186/1742-4682-4-9.
PMCID: PMC1808445
Collective consciousness and its pathologies: Understanding the failure of AIDS control and treatment in the United States
Rodrick M Wallace, Mindy T Fullilove, Robert E Fullilove, and Deborah N Wallace
Theor Biol Med Model. 2007; 4: 10. Published online 2007 February 26. doi: 10.1186/1742-4682-4-10.
PMCID: PMC1820776
A mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis
Evgeniya A Oshchepkova-Nedosekina and Vitalii A Likhoshvai
Theor Biol Med Model. 2007; 4: 11. Published online 2007 February 27. doi: 10.1186/1742-4682-4-11.
PMCID: PMC1808444
Theoretical size distribution of fossil taxa: analysis of a null model
William J Reed and Barry D Hughes
Theor Biol Med Model. 2007; 4: 12. Published online 2007 March 22. doi: 10.1186/1742-4682-4-12.
PMCID: PMC1845141
Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models
Michaela Vossen, Michael Sevestre, Christoph Niederalt, In-Jin Jang, Stefan Willmann, and Andrea N Edginton
Theor Biol Med Model. 2007; 4: 13. Published online 2007 March 26. doi: 10.1186/1742-4682-4-13.
PMCID: PMC1853074
A mathematical model separates quantitatively the cytostatic and cytotoxic effects of a HER2 tyrosine kinase inhibitor
Peter Hinow, Shizhen Emily Wang, Carlos L Arteaga, and Glenn F Webb
Theor Biol Med Model. 2007; 4: 14. Published online 2007 April 3. doi: 10.1186/1742-4682-4-14.
PMCID: PMC1852549
Does reservoir host mortality enhance transmission of West Nile virus?
Ivo M Foppa and Andrew Spielman
Theor Biol Med Model. 2007; 4: 17. Published online 2007 May 11. doi: 10.1186/1742-4682-4-17.
PMCID: PMC1884135
Anomalous ion diffusion within skeletal muscle transverse tubule networks
Paul R Shorten and Tanya K Soboleva
Theor Biol Med Model. 2007; 4: 18. Published online 2007 May 17. doi: 10.1186/1742-4682-4-18.
PMCID: PMC1899483
Distinguishing enzymes using metabolome data for the hybrid dynamic/static method
Nobuyoshi Ishii, Yoichi Nakayama, and Masaru Tomita
Theor Biol Med Model. 2007; 4: 19. Published online 2007 May 20. doi: 10.1186/1742-4682-4-19.
PMCID: PMC1892778
Time variations in the transmissibility of pandemic influenza in Prussia, Germany, from 1918–19
Hiroshi Nishiura
Theor Biol Med Model. 2007; 4: 20. Published online 2007 June 4. doi: 10.1186/1742-4682-4-20.
PMCID: PMC1892008
Optimization principles of dendritic structure
Hermann Cuntz, Alexander Borst, and Idan Segev
Theor Biol Med Model. 2007; 4: 21. Published online 2007 June 8. doi: 10.1186/1742-4682-4-21.
PMCID: PMC1924501
Modeling the effect of levothyroxine therapy on bone mass density in postmenopausal women: a different approach leads to new inference
Babak Mohammadi, Vahid Haghpanah, Seyed Mohammad Tavangar, and Bagher Larijani
Theor Biol Med Model. 2007; 4: 23. Published online 2007 June 9. doi: 10.1186/1742-4682-4-23.
PMCID: PMC1914344
The relationship between twitch depression and twitch fade during neuromuscular block produced by vecuronium: correlation with the release of acetylcholine
Shashi B Bhatt, Jack Kohl, Anton Amann, and Vladimir Nigrovic
Theor Biol Med Model. 2007; 4: 24. Published online 2007 July 16. doi: 10.1186/1742-4682-4-24.
PMCID: PMC1939837
A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose
Anthony J Chalmers, Soeren M Bentzen, and Francesca M Buffa
Theor Biol Med Model. 2007; 4: 25. Published online 2007 July 19. doi: 10.1186/1742-4682-4-25.
PMCID: PMC1950494
Numerical modelling of label-structured cell population growth using CFSE distribution data
Tatyana Luzyanina, Dirk Roose, Tim Schenkel, Martina Sester, Stephan Ehl, Andreas Meyerhans, and Gennady Bocharov
Theor Biol Med Model. 2007; 4: 26. Published online 2007 July 24. doi: 10.1186/1742-4682-4-26.
PMCID: PMC1950697
Can a single model explain both breast cancer and prostate cancer?
A Edward Friedman
Theor Biol Med Model. 2007; 4: 28. Published online 2007 August 1. doi: 10.1186/1742-4682-4-28.
PMCID: PMC2014741
Could increased axial wall stress be responsible for the development of atheroma in the proximal segment of myocardial bridges?
Pierre-André Doriot, Pierre-André Dorsaz, and Jacques Noble
Theor Biol Med Model. 2007; 4: 29. Published online 2007 August 9. doi: 10.1186/1742-4682-4-29.
PMCID: PMC2020464
A continuum mathematical model of endothelial layer maintenance and senescence
Ying Wang, Baltazar D Aguda, and Avner Friedman
Theor Biol Med Model. 2007; 4: 30. Published online 2007 August 10. doi: 10.1186/1742-4682-4-30.
PMCID: PMC1988791
Variance in multiplex suspension array assays: microsphere size variation impact
Brian P Hanley, Li Xing, and R Holland Cheng
Theor Biol Med Model. 2007; 4: 31. Published online 2007 August 23. doi: 10.1186/1742-4682-4-31.
PMCID: PMC2041949
Variance in multiplex suspension array assays: intraplex method improves reliability
Brian Hanley
Theor Biol Med Model. 2007; 4: 32. Published online 2007 August 29. doi: 10.1186/1742-4682-4-32.
PMCID: PMC2000462
Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5)
Aina W Ravna, Ingebrigt Sylte, and Georg Sager
Theor Biol Med Model. 2007; 4: 33. Published online 2007 September 6. doi: 10.1186/1742-4682-4-33.
PMCID: PMC2211457
The allosteric modulation of lipases and its possible biological relevance
Jens Köhler and Bernhard Wünsch
Theor Biol Med Model. 2007; 4: 34. Published online 2007 September 7. doi: 10.1186/1742-4682-4-34.
PMCID: PMC2020465
A discrete Single Delay Model for the Intra-Venous Glucose Tolerance Test
Simona Panunzi, Pasquale Palumbo, and Andrea De Gaetano
Theor Biol Med Model. 2007; 4: 35. Published online 2007 September 12. doi: 10.1186/1742-4682-4-35.
PMCID: PMC2072949
Cable properties and propagation velocity in a long single chain of simulated myocardial cells
Lakshminarayanan Ramasamy and Nicholas Sperelakis
Theor Biol Med Model. 2007; 4: 36. Published online 2007 September 14. doi: 10.1186/1742-4682-4-36.
PMCID: PMC2071913
A statistical approach to estimating the strength of cell-cell interactions under the differential adhesion hypothesis
Mathieu Emily and Olivier François
Theor Biol Med Model. 2007; 4: 37. Published online 2007 September 18. doi: 10.1186/1742-4682-4-37.
PMCID: PMC2213651
Optimization of biotechnological systems through geometric programming
Alberto Marin-Sanguino, Eberhard O Voit, Carlos Gonzalez-Alcon, and Nestor V Torres
Theor Biol Med Model. 2007; 4: 38. Published online 2007 September 26. doi: 10.1186/1742-4682-4-38.
PMCID: PMC2231360
Hypertabastic survival model
Mohammad A Tabatabai, Zoran Bursac, David K Williams, and Karan P Singh
Theor Biol Med Model. 2007; 4: 40. Published online 2007 October 26. doi: 10.1186/1742-4682-4-40.
PMCID: PMC2169222
Analysis of arterial intimal hyperplasia: review and hypothesis
Vladimir M Subbotin
Theor Biol Med Model. 2007; 4: 41. Published online 2007 October 31. doi: 10.1186/1742-4682-4-41.
PMCID: PMC2169223
Coordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift
Fernando Alvarez-Vasquez, Kellie J Sims, Eberhard O Voit, and Yusuf A Hannun
Theor Biol Med Model. 2007; 4: 42. Published online 2007 October 31. doi: 10.1186/1742-4682-4-42.
PMCID: PMC2203994
Regular mosaic pattern development: A study of the interplay between lateral inhibition, apoptosis and differential adhesion
Gregory J Podgorski, Mayank Bansal, and Nicholas S Flann
Theor Biol Med Model. 2007; 4: 43. Published online 2007 October 31. doi: 10.1186/1742-4682-4-43.
PMCID: PMC2203995
Simulation of propofol anaesthesia for intracranial decompression using brain hypothermia treatment
Lu Gaohua and Hidenori Kimura
Theor Biol Med Model. 2007; 4: 46. Published online 2007 November 29. doi: 10.1186/1742-4682-4-46.
PMCID: PMC2217543
Measuring the functional sequence complexity of proteins
Kirk K Durston, David KY Chiu, David L Abel, and Jack T Trevors
Theor Biol Med Model. 2007; 4: 47. Published online 2007 December 6. doi: 10.1186/1742-4682-4-47.
PMCID: PMC2217542
Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia
Tunahan Çakιr, Selma Alsan, Hale Saybaşιlι, Ata Akιn, and Kutlu Ö Ülgen
Theor Biol Med Model. 2007; 4: 48. Published online 2007 December 10. doi: 10.1186/1742-4682-4-48.
PMCID: PMC2246127
A unified framework of immunological and epidemiological dynamics for the spread of viral infections in a simple network-based population
David M Vickers and Nathaniel D Osgood
Theor Biol Med Model. 2007; 4: 49. Published online 2007 December 20. doi: 10.1186/1742-4682-4-49.
PMCID: PMC2248185
Simulating non-small cell lung cancer with a multiscale agent-based model
Zhihui Wang, Le Zhang, Jonathan Sagotsky, and Thomas S Deisboeck
Theor Biol Med Model. 2007; 4: 50. Published online 2007 December 21. doi: 10.1186/1742-4682-4-50.
PMCID: PMC2259313
Reviews
Immunostimulation and Immunoinhibition of Premalignant Lesions
Richmond T Prehn
Theor Biol Med Model. 2007; 4: 6. Published online 2007 February 6. doi: 10.1186/1742-4682-4-6.
PMCID: PMC1797005
Does the immune reaction cause malignant transformation by disrupting cell-to-cell or cell-to-matrix communications?
Richmond T Prehn
Theor Biol Med Model. 2007; 4: 16. Published online 2007 May 4. doi: 10.1186/1742-4682-4-16.
PMCID: PMC1871575
Nonequilibrium thermodynamics and energy efficiency in weight loss diets
Richard D Feinman and Eugene J Fine
Theor Biol Med Model. 2007; 4: 27. Published online 2007 July 30. doi: 10.1186/1742-4682-4-27.
PMCID: PMC1947950
Inflammation: a way to understanding the evolution of portal hypertension
María-Angeles Aller, Jorge-Luis Arias, Arturo Cruz, and Jaime Arias
Theor Biol Med Model. 2007; 4: 44. Published online 2007 November 13. doi: 10.1186/1742-4682-4-44.
PMCID: PMC2206015
The Proteomic Code: a molecular recognition code for proteins
Jan C Biro
Theor Biol Med Model. 2007; 4: 45. Published online 2007 November 13. doi: 10.1186/1742-4682-4-45.
PMCID: PMC2206014
Software
The Basic Immune Simulator: An agent-based model to study the interactions between innate and adaptive immunity
Virginia A Folcik, Gary C An, and Charles G Orosz
Theor Biol Med Model. 2007; 4: 39. Published online 2007 September 27. doi: 10.1186/1742-4682-4-39.
PMCID: PMC2186321
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