Home
Search
Study Topics
Glossary
|
|
|
|
|
|
Sponsors and Collaborators: |
M.D. Anderson Cancer Center Department of Defense AstraZeneca |
---|---|
Information provided by: | M.D. Anderson Cancer Center |
ClinicalTrials.gov Identifier: | NCT00402896 |
Primary Objective:
1. To examine the effect of ZD6474 on the time between placement of an indwelling pleural catheter and its removal.
Secondary Objectives:
Condition | Intervention | Phase |
---|---|---|
Lung Cancer Pleural Effusion |
Drug: ZD6474 |
Phase II |
Study Type: | Interventional |
Study Design: | Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study |
Official Title: | Treatment of Malignant Pleural Effusion With ZD6474, a Novel Vascular Endothelial Growth Factor Receptor (VEGFR) and Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor |
Estimated Enrollment: | 25 |
Study Start Date: | October 2006 |
Estimated Primary Completion Date: | October 2009 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
---|---|
1: Experimental
ZD6474
|
Drug: ZD6474
300 mg/day orally for 10 weeks.
|
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Christine Alden, R.N. | 713-792-0734 | cmalden@mdanderson.org |
United States, Texas | |
U.T.M.D. Anderson Cancer Center | Recruiting |
Houston, Texas, United States, 77030 | |
Contact: Christine Alden, R.N. 713-792-0734 cmalden@mdanderson.org | |
Principal Investigator: Roy S. Herbst, M.D., PhD. |
Principal Investigator: | Roy S. Herbst, M.D., PhD. | U.T.M.D. Anderson Cancer Center |
Responsible Party: | U.T.M.D. Anderson Cancer Center ( Roy S. Herbst, MD, PhD/Professor ) |
Study ID Numbers: | 2005-0929 |
Study First Received: | November 20, 2006 |
Last Updated: | December 22, 2008 |
ClinicalTrials.gov Identifier: | NCT00402896 |
Health Authority: | United States: Food and Drug Administration |
Lung Cancer Non-Small Cell Lung Cancer Pleural Effusion Indwelling Intrapleural Denver Catheter ZD6474 |
Vascular Endothelial Growth Factor Receptor VEGFR Epidermal Growth factor Receptor EGFR Tyrosine Kinase Inhibitor |
Thoracic Neoplasms Pleural Effusion Non-small cell lung cancer Respiratory Tract Diseases Lung Neoplasms Pleural Diseases |
Lung Diseases Pleural Effusion, Malignant Endothelial Growth Factors Carcinoma, Non-Small-Cell Lung Pleural Neoplasms |
Respiratory Tract Neoplasms Neoplasms Neoplasms by Site |
Growth Substances Physiological Effects of Drugs Pharmacologic Actions |