Inclusion Criteria:

• Healthy subject of either gender,
• Age 12 to 18 months,
• Negative clinical history of measles, mumps, rubella, varicella and zoster,
• Consent form signed by both holders of the parental authority or by the legal representative
• Holder(s) of the the parental authority / legal representative able to understand the protocol requirements and to fill in the Diary Card.

Exclusion Criteria:

• Prior receipt of measles, mumps, rubella and/or varicella vaccine either alone or in any combination,
• Any recent (<=30 days) exposure to measles, mumps, rubella, varicella and/or zoster
• Any recent (<= 3 days) history of febrile illness
• Any severe chronic disease,
• Active untreated tuberculosis,
• Known personal history of seizure disorder,
• Any known blood dyscrasias, leukemia, lymphomas of any type, or other malignant neoplasms affecting the haematopoietic and lymphatic systems,
• Any severe thrombocytopenia or any other coagulation disorder that would contraindicate intramuscular injection,
• Any immune impairment or humoral/cellular deficiency, neoplastic disease or depressed immunity,
• Any previous (<= 150 days) receipt of immune globulin or any blood-derived product or scheduled to be administered through Visit 3,
• Any recent (<= 7 days) tuberculin test or scheduled tuberculin test through Visit 3,
• Any recent (<= 30 days) receipt of an inactivated or a live vaccine or scheduled vaccination through Visit 3,