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Volume 354(1386);  June 29, 1999
Huntington's disease: a clinical, genetic and molecular model for polyglutamine repeat disorders.
P S Harper
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 957–961.
PMCID: PMC1692597
Transgenic models of Huntington's disease.
K Sathasivam, C Hobbs, L Mangiarini, A Mahal, M Turmaine, P Doherty, S W Davies, and G P Bates
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 963–969.
PMCID: PMC1692600
From neuronal inclusions to neurodegeneration: neuropathological investigation of a transgenic mouse model of Huntington's disease
S. W. Davies
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 971–979. doi: 10.1098/rstb.1999.0448.
PMCID: PMC1692612
From neuronal inclusions to neurodegeneration: neuropathological investigation of a transgenic mouse model of Huntington's disease.
S W Davies, M Turmaine, B A Cozens, A S Raza, A Mahal, L Mangiarini, and G P Bates
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 981–989.
PMCID: PMC1692604
Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease.
J H Cha, A S Frey, S A Alsdorf, J A Kerner, C M Kosinski, L Mangiarini, J B Penney, Jr, S W Davies, G P Bates, and A B Young
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 981–989.
PMCID: PMC1692608
Aggregation of truncated GST-HD exon 1 fusion proteins containing normal range and expanded glutamine repeats.
B Hollenbach, E Scherzinger, K Schweiger, R Lurz, H Lehrach, and E E Wanker
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 991–994.
PMCID: PMC1692611
Are there multiple pathways in the pathogenesis of Huntington's disease?
N Aronin, M Kim, G Laforet, and M DiFiglia
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 995–1003.
PMCID: PMC1692615
Polyglutamine pathogenesis.
C A Ross, J D Wood, G Schilling, M F Peters, F C Nucifora, Jr, J K Cooper, A H Sharp, R L Margolis, and D R Borchelt
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1005–1011.
PMCID: PMC1692617
Properties of polyglutamine expansion in vitro and in a cellular model for Huntington's disease.
A Lunkes, Y Trottier, J Fagart, P Schultz, G Zeder-Lutz, D Moras, and J L Mandel
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1013–1019.
PMCID: PMC1692598
The localization and interactions of huntingtin.
A L Jones
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1021–1027.
PMCID: PMC1692601
Evidence for a recruitment and sequestration mechanism in Huntington's disease.
E Preisinger, B M Jordan, A Kazantsev, and D Housman
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1029–1034.
PMCID: PMC1692605
Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease.
P H Reddy, V Charles, M Williams, G Miller, W O Whetsell, Jr, and D A Tagle
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1035–1045.
PMCID: PMC1692609
Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease in cell culture and in transgenic mice expressing mutant huntingtin.
A S Hackam, J G Hodgson, R Singaraja, T Zhang, L Gan, C A Gutekunst, S M Hersch, and M R Hayden
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1047–1055.
PMCID: PMC1692613
A genetic model for human polyglutamine-repeat disease in Drosophila melanogaster.
N M Bonini
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1057–1060.
PMCID: PMC1692616
Analysis of the subcellular localization of huntingtin with a set of rabbit polyclonal antibodies in cultured mammalian cells of neuronal origin: comparison with the distribution of huntingtin in Huntington's disease autopsy brain.
J C Dorsman, M A Smoor, M L Maat-Schieman, M Bout, S Siesling, S G van Duinen, J J Verschuuren, J T den Dunnen, R A Roos, and G J van Ommen
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1061–1067.
PMCID: PMC1692596
Molecular pathology of dentatorubral-pallidoluysian atrophy.
I Kanazawa
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1069–1074.
PMCID: PMC1692599
Androgen receptor mutation in Kennedy's disease.
K H Fischbeck, A Lieberman, C K Bailey, A Abel, and D E Merry
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1075–1078.
PMCID: PMC1692603
Progress in pathogenesis studies of spinocerebellar ataxia type 1.
C J Cummings, H T Orr, and H Y Zoghbi
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1079–1081.
PMCID: PMC1692607
CAG-polyglutamine-repeat mutations: independence from gene context.
J M Ordway, J A Cearley, and P J Detloff
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1083–1088.
PMCID: PMC1692602
CAG repeat instability, cryptic sequence variation and pathogeneticity: evidence from different loci.
M Frontali, A Novelletto, G Annesi, and C Jodice
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1089–1094.
PMCID: PMC1692606
Microsatellite and trinucleotide-repeat evolution: evidence for mutational bias and different rates of evolution in different lineages.
D C Rubinsztein, B Amos, and G Cooper
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1095–1099.
PMCID: PMC1692610
Filamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies.
M Goedert
Philos Trans R Soc Lond B Biol Sci. 1999 June 29; 354(1386): 1101–1118.
PMCID: PMC1692614
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