| | This journal provides immediate access to some articles. Editorial Protein Science welcomes new publisher Mark Hermodson PMCID: PMC2249840 Articles The Hans Neurath Award lecture of The Protein Society: Proteins—A testament to physics, chemistry, and evolution Janet M. Thornton PMCID: PMC2249842 Second virial coefficients as a measure of protein–osmolyte interactions Gresham T. Weatherly and Gary J. Pielak PMCID: PMC2249838 Crystal structure of an archaeal DNA sliding clamp: Proliferating cell nuclear antigen from Pyrococcus furiosus Shigeki Matsumiya, Yoshizumi Ishino, and Kosuke Morikawa PMCID: PMC2249843 An engineered leucine zipper a position mutant with an unusual three-state unfolding pathway Hai Zhu, Scott A. Celinski, J. Martin Scholtz, and James C. Hu PMCID: PMC2249852 Differentiation of the slow-binding mechanism for magnesium ion activation and zinc ion inhibition of human placental alkaline phosphatase Hui-Chih Hung and Gu-Gang Chang PMCID: PMC2249836 Stabilizing interactions in the dimer interface of α-subunit in Escherichia coli RNA polymerase: A graph spectral and point mutation study Natarajan Kannan, Preethi Chander, Pallavi Ghosh, Saraswathi Vishveshwara, and Dipankar Chatterji PMCID: PMC2249855 A model of dynamic side-chain–side-chain interactions in the α-lactalbumin molten globule Ping Bai, Jianxing Song, Li Luo, and Zheng-Yu Peng PMCID: PMC2249850 The effect of substrate binding on the conformation and structural stability of Herpes simplex virus type 1 thymidine kinase Christine Wurth, Ulrich Kessler, Joachim Vogt, Georg E. Schulz, Gerd Folkers, and Leonardo Scapozza PMCID: PMC2249856 Characterization of apo and partially saturated states of calerythrin, an EF-hand protein from S. erythraea: A molten globule when deprived of Ca2+ Helena Aitio, Tero Laakso, Tero Pihlajamaa, Mika Torkkeli, Ilkka Kilpeläinen, Torbjörn Drakenberg, Ritva Serimaa, and Arto Annila PMCID: PMC2249847 Solution structure and backbone dynamics of the DNA-binding domain of mouse Sox-5 Peter D. Cary, Christopher M. Read, Ben Davis, Paul C. Driscoll, and Colyn Crane-Robinson PMCID: PMC2249839 Differential chemical labeling of the AlcR DNA-binding domain from Aspergillas nidulans versus its complex with a 16-mer DNA target: Identification of an essential tryptophan involved in the recognition and the interaction with the nucleic acid Gérald Marie, Laurent Serani, Olivier Laprévote, Bertrand Cahuzac, Eric Guittet, and Béatrice Felenbok PMCID: PMC2249835 Structure of soybean seed coat peroxidase: A plant peroxidase with unusual stability and haem-apoprotein interactions Anette Henriksen, Osman Mirza, Chiara Indiani, Kaare Teilum, Giulietta Smulevich, Karen G. Welinder, and Michael Gajhede PMCID: PMC2249845 Testing the role of chain connectivity on the stability and structure of dihydrofolate reductase from E. coli: Fragment complementation and circular permutation reveal stable, alternatively folded forms Virginia F. Smith and C. Robert Matthews PMCID: PMC2249853 A ``loop entropy reduction'' phage-display selection for folded amino acid sequences Philippe Minard, Michelle Scalley-Kim, Alex Watters, and David Baker PMCID: PMC2249851 Molecular dynamics simulation of Escherichia coli dihydrofolate reductase and its protein fragments: Relative stabilities in experiment and simulations Yuk Yin Sham, Buyong Ma, Chung-Jung Tsai, and Ruth Nussinov PMCID: PMC2249846 Disulfide bond effects on protein stability: Designed variants of Cucurbita maxima trypsin inhibitor-V Maria Zavodszky, Chao-Wei Chen, Jenq-Kuen Huang, Michal Zolkiewski, Lisa Wen, and Ramaswamy Krishnamoorthi PMCID: PMC2249841 Understanding thermostability in cytochrome P450 by combinatorial mutagenesis Shelley A. Maves and Stephen G. Sligar PMCID: PMC2249849 A novel target recognition revealed by calmodulin in complex with the basic helix–loop–helix transcription factor SEF2-1/E2-2 Göran Larsson, Jürgen Schleucher, Jacqueline Onions, Stefan Hermann, Thoman Grundström, and Sybren S. Wijmenga PMCID: PMC2249848 Amyloid fibrils derived from the apolipoprotein A1 Leu174Ser variant contain elements of ordered helical structure Palma Mangione, Margaret Sunde, Sofia Giorgetti, Monica Stoppini, Gennaro Esposito, Luca Gianelli, Laura Obici, Lia Asti, Alessia Andreola, Paolo Viglino, Giampaolo Merlini, and Vittorio Bellotti PMCID: PMC2249837 Application of photoaffinity labeling with [3H] all trans- and 9-cis-retinoic acids for characterization of cellular retinoic acid–binding proteins I and II Anna Radominska-Pandya, Guangping Chen, Victor M. Samokyszyn, Joanna M. Little, Walter E. Gall, Gregory Zawada, Nadege Terrier, Jacques Magdalou, and Piotr Czernik PMCID: PMC2249844 For the Record TM Finder: A prediction program for transmembrane protein segments using a combination of hydrophobicity and nonpolar phase helicity scales Charles M. Deber, Chen Wang, Li-Ping Liu, Andrew S. Prior, Shuchi Agrawal, Brenda L. Muskat, and A. Jamie Cuticchia PMCID: PMC2249854 |
