| | This journal provides immediate access to some articles. Research Articles Removal of the N-terminal hexapeptide from human beta2-microglobulin facilitates protein aggregation and fibril formation. G. Esposito, R. Michelutti, G. Verdone, P. Viglino, H. Hernández, C. V. Robinson, A. Amoresano, F. Dal Piaz, M. Monti, P. Pucci, P. Mangione, M. Stoppini, G. Merlini, G. Ferri, and V. Bellotti Protein Sci. 2000 May; 9(5): 831–845. PMCID: PMC2144642 The structure and dynamics in solution of Cu(I) pseudoazurin from Paracoccus pantotrophus. G. S. Thompson, Y. C. Leung, S. J. Ferguson, S. E. Radford, and C. Redfield Protein Sci. 2000 May; 9(5): 846–858. PMCID: PMC2144627 Binding of Zn2+ to a Ca2+ loop allosterically attenuates the activity of factor VIIa and reduces its affinity for tissue factor. L. C. Petersen, O. H. Olsen, L. S. Nielsen, P. O. Freskgård, and E. Persson Protein Sci. 2000 May; 9(5): 859–866. PMCID: PMC2144641 Conformational transitions and fibrillation mechanism of human calcitonin as studied by high-resolution solid-state 13C NMR. M. Kamihira, A. Naito, S. Tuzi, A. Y. Nosaka, and H. Saitô Protein Sci. 2000 May; 9(5): 867–877. PMCID: PMC2144639 Ser45 plays an important role in managing both the equilibrium and transition state energetics of the streptavidin-biotin system. D. E. Hyre, I. Le Trong, S. Freitag, R. E. Stenkamp, and P. S. Stayton Protein Sci. 2000 May; 9(5): 878–885. PMCID: PMC2144626 Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: implications for lipid binding. B. W. Segelke, M. Forstner, M. Knapp, S. D. Trakhanov, S. Parkin, Y. M. Newhouse, H. D. Bellamy, K. H. Weisgraber, and B. Rupp Protein Sci. 2000 May; 9(5): 886–897. PMCID: PMC2144644 Evidence for phosphorylation-dependent conformational changes in methylesterase CheB. G. S. Anand, P. N. Goudreau, J. K. Lewis, and A. M. Stoc Protein Sci. 2000 May; 9(5): 898–906. PMCID: PMC2144634 Alternate modes of binding in two crystal structures of alkaline phosphatase-inhibitor complexes. K. M. Holtz, B. Stec, J. K. Myers, S. M. Antonelli, T. S. Widlanski, and E. R. Kantrowitz Protein Sci. 2000 May; 9(5): 907–915. PMCID: PMC2144633 Comparative model building of interleukin-7 using interleukin-4 as a template: a structural hypothesis that displays atypical surface chemistry in helix D important for receptor activation. L. Cosenza, A. Rosenbach, J. V. White, J. R. Murphy, and T. Smith Protein Sci. 2000 May; 9(5): 916–926. PMCID: PMC2144647 The energetics of phosphate binding to a protein complex. S. P. Edgcomb, B. M. Baker, and K. P. Murphy Protein Sci. 2000 May; 9(5): 927–933. PMCID: PMC2144640 Role of Lys335 in the metastability and function of inhibitory serpins. H. Im and M. H. Yu Protein Sci. 2000 May; 9(5): 934–941. PMCID: PMC2144637 Synthesis and NMR solution structure of an alpha-helical hairpin stapled with two disulfide bridges. P. Barthe, S. Rochette, C. Vita, and C. Roumestand Protein Sci. 2000 May; 9(5): 942–955. PMCID: PMC2144636 Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA. A. D. Ferguson, V. Braun, H. P. Fiedler, J. W. Coulton, K. Diederichs, and W. Welte Protein Sci. 2000 May; 9(5): 956–963. PMCID: PMC2144648 Peptide and metal ion-dependent association of isolated helix-loop-helix calcium binding domains: studies of thrombic fragments of calmodulin. R. D. Brokx and H. J. Vogel Protein Sci. 2000 May; 9(5): 964–975. PMCID: PMC2144632 NMR solution structure of Apis mellifera chymotrypsin/cathepsin G inhibitor-1 (AMCI-1): structural similarity with Ascaris protease inhibitors. T. Cierpicki, J. Bania, and J. Otlewski Protein Sci. 2000 May; 9(5): 976–984. PMCID: PMC2144628 Mutants provide evidence of the importance of glycosydic chains in the activation of lipase 1 from Candida rugosa. S. Brocca, M. Persson, E. Wehtje, P. Adlercreutz, L. Alberghina, and M. Lotti Protein Sci. 2000 May; 9(5): 985–990. PMCID: PMC2144638 Penicillopepsin-JT2, a recombinant enzyme from Penicillium janthinellum and the contribution of a hydrogen bond in subsite S3 to k(cat). Q. N. Cao, M. Stubbs, K. Q. Ngo, M. Ward, A. Cunningham, E. F. Pai, G. C. Tu, and T. Hofmann Protein Sci. 2000 May; 9(5): 991–1001. PMCID: PMC2144643 Characterization of an anti-Borrelia burgdorferi OspA conformational epitope by limited proteolysis of monoclonal antibody-bound antigen and mass spectrometric peptide mapping. V. Legros, C. Jolivet-Reynaud, N. Battail-Poirot, C. Saint-Pierre, and E. Forest Protein Sci. 2000 May; 9(5): 1002–1010. PMCID: PMC2144631 Nonpolar contributions to conformational specificity in assemblies of designed short helical peptides. C. L. Boon and A. Chakrabartty Protein Sci. 2000 May; 9(5): 1011–1023. PMCID: PMC2144635 Post-translational modification is essential for catalytic activity of nitrile hydratase. T. Murakami, M. Nojiri, H. Nakayama, M. Odaka, M. Yohda, N. Dohmae, K. Takio, T. Nagamune, and I. Endo Protein Sci. 2000 May; 9(5): 1024–1030. PMCID: PMC2144646 A model for the sickle hemoglobin fiber using both mutation sites. A. Roufberg and F. A. Ferrone Protein Sci. 2000 May; 9(5): 1031–1034. PMCID: PMC2144645 Temperature-sensitive suppressor mutations of the Escherichia coli DNA gyrase B protein. S. J. Blance, N. L. Williams, Z. A. Preston, J. Bishara, M. S. Smyth, and A. Maxwell Protein Sci. 2000 May; 9(5): 1035–1037. PMCID: PMC2144630 NMR characterization of a pH-dependent equilibrium between two folded solution conformations of the pheromone-binding protein from Bombyx mori. F. Damberger, L. Nikonova, R. Horst, G. Peng, W. S. Leal, and K. Wüthrich Protein Sci. 2000 May; 9(5): 1038–1041. PMCID: PMC2144629 |