Skip Navigation

HazMap: Occupational Exposure to Hazardous Agents
HazMap Home SIS Home NLM Home

as Search Agents Search Diseases Search Jobs Full Text Search


Haz-Map Home on-tab Custom Search on-tab Help on-tab Web Glossary on-tab Reference on-tab
left corner Browse Haz-Map
right corner
Agent Name Caprolactam
CAS Number 105-60-2
Formula C6-H11-N-O
Major Category Plastics & Rubber
Synonyms 1,6-Hexalactam; 1,6-Hexolactam; 1-Aza-2-cycloheptanone; 2-Azacycloheptanone; 2-Ketohexamethylenimine; 2-Oxohexamethyleneimine; 2-Oxohexamethylenimine; 2-Perhydroazepinone; 2H-Azepin-2-one, hexahydro-; 2H-Azepin-7-one, hexahydro-; 6-Aminocaproic acid lactam; 6-Aminohexanoic acid cyclic lactam; 6-Caprolactam; 6-Hexanelactam; A1030; Aminocaproic lactam; Caprolactam; Caprolactam monomer; Caprolattame [French]; Capron PK4; Cyclohexanone iso-oxime; Epsylon kaprolaktam [Polish]; Extrom 6N; Hexahydro-2-azepinone; Hexahydro-2H-azepin-2-one; Hexamethylenimine, 2-oxo-; Hexanoic acid, 6-amino-, cyclic lactam; Hexanoic acid, 6-amino-, lactam; Hexanolactam; Hexanone isoxime; Hexanonisoxim [German]; Kapromine; Stilon; e-Kaprolaktam [Czech]; epsilon-Caprolactam; [ChemIDplus] UN8027
Category Other Monomers
Description White, crystalline solid or flakes with an unpleasant odor; Note: Significant vapor concentrations would be expected only at elevated temperatures; [NIOSH]
Sources/Uses Used as "a monomer for synthetic fibers, plastics, coatings, plasticizers, and paint vehicles and as a cross-linking agent for polyurethanes." [ACGIH]
Comments May cause skin sensitization; A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC] Liver and kidney changes occur in subchronic animal studies using intraperitoneal doses. [ACGIH]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 5 mg/m3, inhalable fraction and vapor
MAK 5 mg/m3, inhalable fraction(dust and vapor)
Vapor Pressure 0.0019 mm Hg
Lethal Concentration LC50 (rats) = 300 mg/m3/2h
Explanatory Notes Flash point = 110 deg C;
Reference Link International Chemical Safety Cards (WHO/IPCS/ILO)
Adverse Effects
Skin Sensitizer Yes
Neurotoxin Other CNS Neurotoxin
Hepatotoxin Hepatotoxin, Secondary
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: CAPROLACTAM  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





Specialized Information Services   U.S. National Library of Medicine,
8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health
Privacy/Disclaimer Notice
Customer Service: tehip@teh.nlm.nih.gov
Last updated: January, 2009