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Volume 4(4);  April 2008
Education
A Quick Guide for Computer-Assisted Instruction in Computational Biology and Bioinformatics
Manuel João Costa, Eduardo Galembeck, Guilherme A. Marson, and Bayardo B. Torres
PLoS Comput Biol. 2008 April; 4(4): e1000035. Published online 2008 April 25. doi: 10.1371/journal.pcbi.1000035.
PMCID: PMC2324196
Perspective
Bioinformatics in China: A Personal Perspective
Liping Wei and Jun Yu
PLoS Comput Biol. 2008 April; 4(4): e1000020. Published online 2008 April 25. doi: 10.1371/journal.pcbi.1000020.
PMCID: PMC2291564
Review
Translational Systems Biology of Inflammation
Yoram Vodovotz, Marie Csete, John Bartels, Steven Chang, and Gary An
PLoS Comput Biol. 2008 April; 4(4): e1000014. Published online 2008 April 25. doi: 10.1371/journal.pcbi.1000014.
PMCID: PMC2329781
Research Articles
Dimensionality and Dynamics in the Behavior of C. elegans
Greg J. Stephens, Bethany Johnson-Kerner, William Bialek, and William S. Ryu
PLoS Comput Biol. 2008 April; 4(4): e1000028. Published online 2008 April 25. doi: 10.1371/journal.pcbi.1000028.
PMCID: PMC2276863
A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus Approach
Peng Wang, John Sidney, Courtney Dow, Bianca Mothé, Alessandro Sette, and Bjoern Peters
PLoS Comput Biol. 2008 April; 4(4): e1000048. Published online 2008 April 4. doi: 10.1371/journal.pcbi.1000048.
PMCID: PMC2267221
Biosynthetic Potentials of Metabolites and Their Hierarchical Organization
Franziska Matthäus, Carlos Salazar, and Oliver Ebenhöh
PLoS Comput Biol. 2008 April; 4(4): e1000049. Published online 2008 April 4. doi: 10.1371/journal.pcbi.1000049.
PMCID: PMC2289774
The Statistical Neuroanatomy of Frontal Networks in the Macaque
Bruno B. Averbeck and Moonsang Seo
PLoS Comput Biol. 2008 April; 4(4): e1000050. Published online 2008 April 4. doi: 10.1371/journal.pcbi.1000050.
PMCID: PMC2268011
Evaluation of Paired-End Sequencing Strategies for Detection of Genome Rearrangements in Cancer
Ali Bashir, Stanislav Volik, Colin Collins, Vineet Bafna, and Benjamin J. Raphael
PLoS Comput Biol. 2008 April; 4(4): e1000051. Published online 2008 April 25. doi: 10.1371/journal.pcbi.1000051.
PMCID: PMC2278375
Genome-Wide Prediction of SH2 Domain Targets Using Structural Information and the FoldX Algorithm
Ignacio E. Sánchez, Pedro Beltrao, Francois Stricher, Joost Schymkowitz, Jesper Ferkinghoff-Borg, Frederic Rousseau, and Luis Serrano
PLoS Comput Biol. 2008 April; 4(4): e1000052. Published online 2008 April 4. doi: 10.1371/journal.pcbi.1000052.
PMCID: PMC2271153
Efficient Olfactory Coding in the Pheromone Receptor Neuron of a Moth
Lubomir Kostal, Petr Lansky, and Jean-Pierre Rospars
PLoS Comput Biol. 2008 April; 4(4): e1000053. Published online 2008 April 25. doi: 10.1371/journal.pcbi.1000053.
PMCID: PMC2291565
Predicting Co-Complexed Protein Pairs from Heterogeneous Data
Jian Qiu and William Stafford Noble
PLoS Comput Biol. 2008 April; 4(4): e1000054. Published online 2008 April 18. doi: 10.1371/journal.pcbi.1000054.
PMCID: PMC2275314
The Role of Elastic Stresses on Leaf Venation Morphogenesis
Maria F. Laguna, Steffen Bohn, and Eduardo A. Jagla
PLoS Comput Biol. 2008 April; 4(4): e1000055. Published online 2008 April 11. doi: 10.1371/journal.pcbi.1000055.
PMCID: PMC2275310
A Generalized Allosteric Mechanism for cis-Regulated Cyclic Nucleotide Binding Domains
Alexandr P. Kornev, Susan S. Taylor, and Lynn F. Ten Eyck
PLoS Comput Biol. 2008 April; 4(4): e1000056. Published online 2008 April 11. doi: 10.1371/journal.pcbi.1000056.
PMCID: PMC2275311
Investigations of Oligonucleotide Usage Variance Within and Between Prokaryotes
Jon Bohlin, Eystein Skjerve, and David W. Ussery
PLoS Comput Biol. 2008 April; 4(4): e1000057. Published online 2008 April 18. doi: 10.1371/journal.pcbi.1000057.
PMCID: PMC2289840
The Emergence and Fate of Horizontally Acquired Genes in Escherichia coli
Mark W. J. van Passel, Pradeep Reddy Marri, and Howard Ochman
PLoS Comput Biol. 2008 April; 4(4): e1000059. Published online 2008 April 11. doi: 10.1371/journal.pcbi.1000059.
PMCID: PMC2275313
Binding-Induced Folding of a Natively Unstructured Transcription Factor
Adrian Gustavo Turjanski, J. Silvio Gutkind, Robert B. Best, and Gerhard Hummer
PLoS Comput Biol. 2008 April; 4(4): e1000060. Published online 2008 April 11. doi: 10.1371/journal.pcbi.1000060.
PMCID: PMC2289845
Distinct Timing Mechanisms Produce Discrete and Continuous Movements
Raoul Huys, Breanna E. Studenka, Nicole L. Rheaume, Howard N. Zelaznik, and Viktor K. Jirsa
PLoS Comput Biol. 2008 April; 4(4): e1000061. Published online 2008 April 25. doi: 10.1371/journal.pcbi.1000061.
PMCID: PMC2329590
Synaptic Learning Rules and Sparse Coding in a Model Sensory System
Luca A. Finelli, Seth Haney, Maxim Bazhenov, Mark Stopfer, and Terrence J. Sejnowski
PLoS Comput Biol. 2008 April; 4(4): e1000062. Published online 2008 April 18. doi: 10.1371/journal.pcbi.1000062.
PMCID: PMC2278376
Functional Maps of Protein Complexes from Quantitative Genetic Interaction Data
Sourav Bandyopadhyay, Ryan Kelley, Nevan J. Krogan, and Trey Ideker
PLoS Comput Biol. 2008 April; 4(4): e1000065. Published online 2008 April 18. doi: 10.1371/journal.pcbi.1000065.
PMCID: PMC2289880
An AP Endonuclease 1–DNA Polymerase β Complex: Theoretical Prediction of Interacting Surfaces
Alexej Abyzov, Alper Uzun, Phyllis R. Strauss, and Valentin A. Ilyin
PLoS Comput Biol. 2008 April; 4(4): e1000066. Published online 2008 April 25. doi: 10.1371/journal.pcbi.1000066.
PMCID: PMC2289873
Performance and Scalability of Discriminative Metrics for Comparative Gene Identification in 12 Drosophila Genomes
Michael F. Lin, Ameya N. Deoras, Matthew D. Rasmussen, and Manolis Kellis
PLoS Comput Biol. 2008 April; 4(4): e1000067. Published online 2008 April 18. doi: 10.1371/journal.pcbi.1000067.
PMCID: PMC2291194
Correction
Correction: Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics
Stephen A. Ramsey, Sandy L. Klemm, Daniel E. Zak, Kathleen A. Kennedy, Vesteinn Thorsson, Bin Li, Mark Gilchrist, Elizabeth S. Gold, Carrie D. Johnson, Vladimir Litvak, Garnet Navarro, Jared C. Roach, Carrie M. Rosenberger, Alistair G. Rust, Natalya Yudkovsky, Alan Aderem, and Ilya Shmulevich
PLoS Comput Biol. 2008 April; 4(4): 10.1371/annotation/e14ad837-e5ff-4bd5-a5f2-f32e784d75a2. Published online 2008 April 2. doi: 10.1371/annotation/e14ad837-e5ff-4bd5-a5f2-f32e784d75a2.
PMCID: PMC2637085
Corrects: Stephen A. Ramsey, et al. Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics. PLoS Comput Biol. 2008 March; 4(3): e1000021.
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