| | Education A Primer on Python for Life Science Researchers Sebastian Bassi PLoS Comput Biol. 2007 November; 3(11): e199. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030199.PMCID: PMC2098836 Editorial Ten Simple Rules for Graduate Students Jenny Gu and Philip E Bourne PLoS Comput Biol. 2007 November; 3(11): e229. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030229.PMCID: PMC2098857 Perspectives Computational Biology in Cuba: An Opportunity to Promote Science in a Developing Country Tirso Pons, Luis A Montero, and Juan P Febles PLoS Comput Biol. 2007 November; 3(11): e227. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030227.PMCID: PMC2098855 Research Articles Phenotypic Mutation Rates and the Abundance of Abnormal Proteins in Yeast Martin Willensdorfer, Reinhard Bürger, and Martin A Nowak PLoS Comput Biol. 2007 November; 3(11): e203. Prepublished online 2007 September 6. Published online 2007 November 23. doi: 10.1371/journal.pcbi.0030203.PMCID: PMC2082502 From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses Sven Zenker, Jonathan Rubin, and Gilles Clermont PLoS Comput Biol. 2007 November; 3(11): e204. Prepublished online 2007 September 6. Published online 2007 November 9. doi: 10.1371/journal.pcbi.0030204.PMCID: PMC2065888 Meta-Analysis of Drosophila Circadian Microarray Studies Identifies a Novel Set of Rhythmically Expressed Genes Kevin P Keegan, Suraj Pradhan, Ji-Ping Wang, and Ravi Allada PLoS Comput Biol. 2007 November; 3(11): e208. Prepublished online 2007 September 11. Published online 2007 November 2. doi: 10.1371/journal.pcbi.0030208.PMCID: PMC2098839 Are There Rearrangement Hotspots in the Human Genome? Max A Alekseyev and Pavel A Pevzner PLoS Comput Biol. 2007 November; 3(11): e209. Prepublished online 2007 September 14. Published online 2007 November 9. doi: 10.1371/journal.pcbi.0030209.PMCID: PMC2065889 Self-Assembly and DNA Binding of the Blocking Factor in X Chromosome Inactivation Mario Nicodemi and Antonella Prisco PLoS Comput Biol. 2007 November; 3(11): e210. Prepublished online 2007 September 18. Published online 2007 November 9. doi: 10.1371/journal.pcbi.0030210.PMCID: PMC2065890 Detecting Coevolution in and among Protein Domains Chen-Hsiang Yeang and David Haussler PLoS Comput Biol. 2007 November; 3(11): e211. Prepublished online 2007 September 18. Published online 2007 November 2. doi: 10.1371/journal.pcbi.0030211.PMCID: PMC2098842 Self-organizing Mechanism for Development of Space-filling Neuronal Dendrites Kaoru Sugimura, Kohei Shimono, Tadashi Uemura, and Atsushi Mochizuki PLoS Comput Biol. 2007 November; 3(11): e212. Published online 2007 November 16. doi: 10.1371/journal.pcbi.0030212.PMCID: PMC2077899 Where Have All the Interactions Gone? Estimating the Coverage of Two-Hybrid Protein Interaction Maps Hailiang Huang, Bruno M Jedynak, and Joel S Bader PLoS Comput Biol. 2007 November; 3(11): e214. Prepublished online 2007 September 21. Published online 2007 November 23. doi: 10.1371/journal.pcbi.0030214.PMCID: PMC2082503 A Nucleosome-Guided Map of Transcription Factor Binding Sites in Yeast Leelavati Narlikar, Raluca Gordân, and Alexander J Hartemink PLoS Comput Biol. 2007 November; 3(11): e215. Prepublished online 2007 September 24. Published online 2007 November 9. doi: 10.1371/journal.pcbi.0030215.PMCID: PMC2065891 MORPH: Probabilistic Alignment Combined with Hidden Markov Models of cis-Regulatory Modules Saurabh Sinha and Xin He PLoS Comput Biol. 2007 November; 3(11): e216. Prepublished online 2007 September 24. Published online 2007 November 9. doi: 10.1371/journal.pcbi.0030216.PMCID: PMC2065892 In Silico Elucidation of the Molecular Mechanism Defining the Adverse Effect of Selective Estrogen Receptor Modulators Lei Xie, Jian Wang, and Philip E Bourne PLoS Comput Biol. 2007 November; 3(11): e217. Prepublished online 2007 September 26. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030217.PMCID: PMC2098847 Stochastic Noise and Synchronisation during Dictyostelium Aggregation Make cAMP Oscillations Robust Jongrae Kim, Pat Heslop-Harrison, Ian Postlethwaite, and Declan G Bates PLoS Comput Biol. 2007 November; 3(11): e218. Prepublished online 2007 September 26. Published online 2007 November 9. doi: 10.1371/journal.pcbi.0030218.PMCID: PMC2065893 From Endosymbiont to Host-Controlled Organelle: The Hijacking of Mitochondrial Protein Synthesis and Metabolism Toni Gabaldón and Martijn A Huynen PLoS Comput Biol. 2007 November; 3(11): e219. Prepublished online 2007 September 26. Published online 2007 November 2. doi: 10.1371/journal.pcbi.0030219.PMCID: PMC2062474 Control of Membrane Fusion Mechanism by Lipid Composition: Predictions from Ensemble Molecular Dynamics Peter M Kasson and Vijay S Pande PLoS Comput Biol. 2007 November; 3(11): e220. Prepublished online 2007 September 26. Published online 2007 November 16. doi: 10.1371/journal.pcbi.0030220.PMCID: PMC2077900 STDP in a Bistable Synapse Model Based on CaMKII and Associated Signaling Pathways Michael Graupner and Nicolas Brunel PLoS Comput Biol. 2007 November; 3(11): e221. Prepublished online 2007 September 26. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030221.PMCID: PMC2098851 Computational Analysis of Mouse piRNA Sequence and Biogenesis Doron Betel, Robert Sheridan, Debora S Marks, and Chris Sander PLoS Comput Biol. 2007 November; 3(11): e222. Prepublished online 2007 September 26. Published online 2007 November 9. doi: 10.1371/journal.pcbi.0030222.PMCID: PMC2065894 Genetic Progression and the Waiting Time to Cancer Niko Beerenwinkel, Tibor Antal, David Dingli, Arne Traulsen, Kenneth W Kinzler, Victor E Velculescu, Bert Vogelstein, and Martin A Nowak PLoS Comput Biol. 2007 November; 3(11): e225. Published online 2007 November 9. doi: 10.1371/journal.pcbi.0030225.PMCID: PMC2065895 Molecular Basis for Evolving Modularity in the Yeast Protein Interaction Network Ariel Fernández PLoS Comput Biol. 2007 November; 3(11): e226. Published online 2007 November 9. doi: 10.1371/journal.pcbi.0030226.PMCID: PMC2065896 A Dynamical Systems Hypothesis of Schizophrenia Marco Loh, Edmund T Rolls, and Gustavo Deco PLoS Comput Biol. 2007 November; 3(11): e228. Published online 2007 November 9. doi: 10.1371/journal.pcbi.0030228.PMCID: PMC2065887 Using Likelihood-Free Inference to Compare Evolutionary Dynamics of the Protein Networks of H. pylori and P. falciparum Oliver Ratmann, Ole Jørgensen, Trevor Hinkley, Michael Stumpf, Sylvia Richardson, and Carsten Wiuf PLoS Comput Biol. 2007 November; 3(11): e230. Prepublished online 2007 October 9. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030230.PMCID: PMC2098858 An Evolutionary-Network Model Reveals Stratified Interactions in the V3 Loop of the HIV-1 Envelope Art F. Y Poon, Fraser I Lewis, Sergei L. Kosakovsky Pond, and Simon D. W Frost PLoS Comput Biol. 2007 November; 3(11): e231. Prepublished online 2007 October 11. Published online 2007 November 23. doi: 10.1371/journal.pcbi.0030231.PMCID: PMC2082504 CATHEDRAL: A Fast and Effective Algorithm to Predict Folds and Domain Boundaries from Multidomain Protein Structures Oliver C Redfern, Andrew Harrison, Tim Dallman, Frances M. G Pearl, and Christine A Orengo PLoS Comput Biol. 2007 November; 3(11): e232. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030232.PMCID: PMC2098860 Small Regulatory RNAs May Sharpen Spatial Expression Patterns Erel Levine, Peter McHale, and Herbert Levine PLoS Comput Biol. 2007 November; 3(11): e233. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030233.PMCID: PMC2098861 A Universal Mechanism Ties Genotype to Phenotype in Trinucleotide Diseases Shai Kaplan, Shalev Itzkovitz, and Ehud Shapiro PLoS Comput Biol. 2007 November; 3(11): e235. Prepublished online 2007 October 16. Published online 2007 November 23. doi: 10.1371/journal.pcbi.0030235.PMCID: PMC2082501 Gamma Oscillations of Spiking Neural Populations Enhance Signal Discrimination Naoki Masuda and Brent Doiron PLoS Comput Biol. 2007 November; 3(11): e236. Prepublished online 2007 October 17. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030236.PMCID: PMC2098863 Predicting Protein Function with Hierarchical Phylogenetic Profiles: The Gene3D Phylo-Tuner Method Applied to Eukaryotic Genomes Juan A. G Ranea, Corin Yeats, Alastair Grant, and Christine A Orengo PLoS Comput Biol. 2007 November; 3(11): e237. Prepublished online 2007 March 18. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030237.PMCID: PMC2098864 Intragenomic Matching Reveals a Huge Potential for miRNA-Mediated Regulation in Plants Morten Lindow, Anders Jacobsen, Sanne Nygaard, Yuan Mang, and Anders Krogh PLoS Comput Biol. 2007 November; 3(11): e238. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030238.PMCID: PMC2098865 Predicting Gene Expression from Sequence: A Reexamination Yuan Yuan, Lei Guo, Lei Shen, and Jun S Liu PLoS Comput Biol. 2007 November; 3(11): e243. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030243.PMCID: PMC2098866 Direct Inference of SNP Heterozygosity Rates and Resolution of LOH Detection Xiaohong Li, Steven G Self, Patricia C Galipeau, Thomas G Paulson, and Brian J Reid PLoS Comput Biol. 2007 November; 3(11): e244. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030244.PMCID: PMC2098867 Retinal Wave Behavior through Activity- Dependent Refractory Periods Keith B Godfrey and Nicholas V Swindale PLoS Comput Biol. 2007 November; 3(11): e245. Published online 2007 November 30. doi: 10.1371/journal.pcbi.0030245.PMCID: PMC2098868 |