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Volume 1(7); December 2005 Message from ISCB Perspectives Time to Organize the Bioinformatics Resourceome PMCID: PMC1323464 Research Articles PhyloGibbs: A Gibbs Sampling Motif Finder That Incorporates Phylogeny PMCID: PMC1309704 The Activity Reaction Core and Plasticity of Metabolic Networks PMCID: PMC1314881 Revealing Posttranscriptional Regulatory Elements Through Network-Level Conservation PMCID: PMC1309705 Folding Free Energies of 5′-UTRs Impact Post-Transcriptional Regulation on a Genomic Scale in Yeast PMCID: PMC1309706 Selective Constraint on Noncoding Regions of Hominid Genomes PMCID: PMC1314883 Genome Trees from Conservation Profiles PMCID: PMC1314884 New Maximum Likelihood Estimators for Eukaryotic Intron Evolution PMCID: PMC1323467 | ||