Anesthetic: An agent that causes insensitivity to pain.

Central nervous system: The brain and spinal cord.

Dementia: A condition of deteriorated mental function.

Dopamine: A neurotransmitter present in regions of the brain that regulate movement, emotion, motivation, and feeling of pleasure.

Epidemiology: The sum of the factors controlling the presence or absence of a disease or condition.

Toxic: Causing temporary or permanent effects that are detrimental to the functioning of a body organ or group of organs.

Withdrawal: A variety of symptoms that occur after use of an addictive drug is reduced or stopped.

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