| | Synopses Chemical and Genetic Screens Hit the Target in Cytokinesis PLoS Biol. 2004 December; 2(12): e386. Published online 2004 October 5. doi: 10.1371/journal.pbio.0020386.PMCID: PMC528724 Taking Stock of Biodiversity to Stem Its Rapid Decline PLoS Biol. 2004 December; 2(12): e413. Published online 2004 October 26. doi: 10.1371/journal.pbio.0020413.PMCID: PMC524260 Computational Mapping of Complex Traits in the Mouse PLoS Biol. 2004 December; 2(12): e425. Published online 2004 November 9. doi: 10.1371/journal.pbio.0020425.PMCID: PMC526181 Repetitive Editing and RNA Splicing PLoS Biol. 2004 December; 2(12): e426. Published online 2004 November 9. doi: 10.1371/journal.pbio.0020426.PMCID: PMC526182 A Structural Analysis of Eukaryotic Membrane Evolution PLoS Biol. 2004 December; 2(12): e428. Published online 2004 November 2. doi: 10.1371/journal.pbio.0020428.PMCID: PMC524474 All HEPped Up about Methylation PLoS Biol. 2004 December; 2(12): e433. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020433.PMCID: PMC529320 Are Animals As Irrational As Humans? PLoS Biol. 2004 December; 2(12): e434. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020434.PMCID: PMC529321 Fungus Holds Clues to the Evolution of Sex Chromosomes PLoS Biol. 2004 December; 2(12): e435. Published online 2004 November 9. doi: 10.1371/journal.pbio.0020435.PMCID: PMC526377 Computer Simulation of the Movement of Listeria Bacteria PLoS Biol. 2004 December; 2(12): e436. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020436.PMCID: PMC532394 A Neuron Survival Protein May Give Directions, Too PLoS Biol. 2004 December; 2(12): e437. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020437.PMCID: PMC529322 In Times of Stress, Mutate Early and Often PLoS Biol. 2004 December; 2(12): e438. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020438.PMCID: PMC529323 Genes, Genomes, and the Road to Diversity: How Regulatory Networks Evolve PLoS Biol. 2004 December; 2(12): e441. Published online 2004 November 9. doi: 10.1371/journal.pbio.0020441.PMCID: PMC526183 Retroviral Gene Vectors Show Clear Target Preferences PLoS Biol. 2004 December; 2(12): e443. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020443.PMCID: PMC529324 This Is Your Fly's Brain on Drugs PLoS Biol. 2004 December; 2(12): e444. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020444.PMCID: PMC529325 Norovirus Cultured for the First Time PLoS Biol. 2004 December; 2(12): e445. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020445.PMCID: PMC532395 When Immune Defenses Turn Traitor PLoS Biol. 2004 December; 2(12): e446. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020446.PMCID: PMC532396 The History of the Intron—Balancing Gains and Losses PLoS Biol. 2004 December; 2(12): e447. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020447.PMCID: PMC532397 Using Biology to Create Complex Patterns PLoS Biol. 2004 December; 2(12): e448. Published online 2004 December 7. doi: 10.1371/journal.pbio.0020448.PMCID: PMC534811 Cro-Magnons Conquered Europe, but Left Neanderthals Alone PLoS Biol. 2004 December; 2(12): e449. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020449.PMCID: PMC532398 A Fly Enzyme for Motor Control PLoS Biol. 2004 December; 2(12): e450. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020450.PMCID: PMC532399 A Global View of Gene Expression in the Aging Kidney PLoS Biol. 2004 December; 2(12): e451. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020451.PMCID: PMC532400 An Evolutionary View of Tiger Conservation PLoS Biol. 2004 December; 2(12): e453. Published online 2004 December 7. doi: 10.1371/journal.pbio.0020453.PMCID: PMC534812 Getting a Whiff of Speciation by Reinforcement PLoS Biol. 2004 December; 2(12): e454. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020454.PMCID: PMC535576 Essay Mathematics Is Biology's Next Microscope, Only Better; Biology Is Mathematics' Next Physics, Only Better Joel E Cohen PLoS Biol. 2004 December; 2(12): e439. Published online 2004 December 14. doi: 10.1371/journal.pbio.0020439.PMCID: PMC535574 Feature Ecology's Big, Hot Idea John Whitfield PLoS Biol. 2004 December; 2(12): e440. Published online 2004 December 14. doi: 10.1371/journal.pbio.0020440.PMCID: PMC535575 Book Review/Science in the Media Brain versus Machine Control Jose M Carmena PLoS Biol. 2004 December; 2(12): e430. Published online 2004 December 14. doi: 10.1371/journal.pbio.0020430.PMCID: PMC535572 Obituary Francis Crick's Legacy for Neuroscience: Between the α and the Ω Ralph M Siegel and Edward M Callaway PLoS Biol. 2004 December; 2(12): e419. Published online 2004 December 14. doi: 10.1371/journal.pbio.0020419.PMCID: PMC535570 Primer The What and Why of Research on Reinforcement Maria R Servedio PLoS Biol. 2004 December; 2(12): e420. Published online 2004 December 14. doi: 10.1371/journal.pbio.0020420.PMCID: PMC535571 The Emergence of Complexity: Lessons from DNA Chengde Mao PLoS Biol. 2004 December; 2(12): e431. Published online 2004 December 14. doi: 10.1371/journal.pbio.0020431.PMCID: PMC535573 Community Page Regional Societies: Fostering Competitive Research Through Virtual Infrastructures Steven F Jennings, Andrey A Ptitsyn, Dawn Wilkins, Russel E Bruhn, William Slikker, Jr, and Jonathan D Wren PLoS Biol. 2004 December; 2(12): e372. Published online 2004 December 14. doi: 10.1371/journal.pbio.0020372.PMCID: PMC535569 Research Articles Parallel Chemical Genetic and Genome-Wide RNAi Screens Identify Cytokinesis Inhibitors and Targets Ulrike S Eggert, Amy A Kiger, Constance Richter, Zachary E Perlman, Norbert Perrimon, Timothy J Mitchison, and Christine M Field PLoS Biol. 2004 December; 2(12): e379. Published online 2004 October 5. doi: 10.1371/journal.pbio.0020379.PMCID: PMC528723 Components of Coated Vesicles and Nuclear Pore Complexes Share a Common Molecular Architecture Damien Devos, Svetlana Dokudovskaya, Frank Alber, Rosemary Williams, Brian T Chait, Andrej Sali, and Michael P Rout PLoS Biol. 2004 December; 2(12): e380. Published online 2004 November 2. doi: 10.1371/journal.pbio.0020380.PMCID: PMC524472 Measuring Global Trends in the Status of Biodiversity: Red List Indices for Birds Stuart H. M Butchart, Alison J Stattersfield, Leon A Bennun, Sue M Shutes, H. Resit Akçakaya, Jonathan E. M Baillie, Simon N Stuart, Craig Hilton-Taylor, and Georgina M Mace PLoS Biol. 2004 December; 2(12): e383. Published online 2004 October 26. doi: 10.1371/journal.pbio.0020383.PMCID: PMC524254 Convergent Evolution of Chromosomal Sex-Determining Regions in the Animal and Fungal Kingdoms James A Fraser, Stephanie Diezmann, Ryan L Subaran, Andria Allen, Klaus B Lengeler, Fred S Dietrich, and Joseph Heitman PLoS Biol. 2004 December; 2(12): e384. Published online 2004 November 9. doi: 10.1371/journal.pbio.0020384.PMCID: PMC526376 Widespread A-to-I RNA Editing of Alu-Containing mRNAs in the Human Transcriptome Alekos Athanasiadis, Alexander Rich, and Stefan Maas PLoS Biol. 2004 December; 2(12): e391. Published online 2004 November 9. doi: 10.1371/journal.pbio.0020391.PMCID: PMC526178 Use of a Dense Single Nucleotide Polymorphism Map for In Silico Mapping in the Mouse Mathew T Pletcher, Philip McClurg, Serge Batalov, Andrew I Su, S. Whitney Barnes, Erica Lagler, Ron Korstanje, Xiaosong Wang, Deborah Nusskern, Molly A Bogue, Richard J Mural, Beverly Paigen, and Tim Wiltshire PLoS Biol. 2004 December; 2(12): e393. Published online 2004 November 9. doi: 10.1371/journal.pbio.0020393.PMCID: PMC526179 Conservation and Evolution of Cis-Regulatory Systems in Ascomycete Fungi Audrey P Gasch, Alan M Moses, Derek Y Chiang, Hunter B Fraser, Mark Berardini, and Michael B Eisen PLoS Biol. 2004 December; 2(12): e398. Published online 2004 November 9. doi: 10.1371/journal.pbio.0020398.PMCID: PMC526180 Adaptive Amplification and Point Mutation Are Independent Mechanisms: Evidence for Various Stress-Inducible Mutation Mechanisms P. J Hastings, Andrew Slack, Joseph F Petrosino, and Susan M Rosenberg PLoS Biol. 2004 December; 2(12): e399. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020399.PMCID: PMC529313 State-Dependent Decisions Cause Apparent Violations of Rationality in Animal Choice Cynthia Schuck-Paim, Lorena Pompilio, and Alex Kacelnik PLoS Biol. 2004 December; 2(12): e402. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020402.PMCID: PMC529314 A Chemoattractant Role for NT-3 in Proprioceptive Axon Guidance Barış Genç, P. Hande Özdinler, April E Mendoza, and Reha S Erzurumlu PLoS Biol. 2004 December; 2(12): e403. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020403.PMCID: PMC529315 DNA Methylation Profiling of the Human Major Histocompatibility Complex: A Pilot Study for the Human Epigenome Project Vardhman K Rakyan, Thomas Hildmann, Karen L Novik, Jörn Lewin, Jörg Tost, Antony V Cox, T. Dan Andrews, Kevin L Howe, Thomas Otto, Alexander Olek, Judith Fischer, Ivo G Gut, Kurt Berlin, and Stephan Beck PLoS Biol. 2004 December; 2(12): e405. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020405.PMCID: PMC529316 Lmo Mutants Reveal a Novel Role for Circadian Pacemaker Neurons in Cocaine-Induced Behaviors Linus T.-Y Tsai, Roland J Bainton, Justin Blau, and Ulrike Heberlein PLoS Biol. 2004 December; 2(12): e408. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020408.PMCID: PMC529317 In Silico Reconstitution of Listeria Propulsion Exhibits Nano-Saltation Jonathan B Alberts and Garrett M Odell PLoS Biol. 2004 December; 2(12): e412. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020412.PMCID: PMC532387 The Genetics of Speciation by Reinforcement Daniel Ortiz-Barrientos, Brian A Counterman, and Mohamed A. F Noor PLoS Biol. 2004 December; 2(12): e416. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020416.PMCID: PMC529318 Secreted Bacterial Effectors and Host-Produced Eiger/TNF Drive Death in a Salmonella-Infected Fruit Fly Stephanie M Brandt, Marc S Dionne, Ranjiv S Khush, Linh N Pham, Thomas J Vigdal, and David S Schneider PLoS Biol. 2004 December; 2(12): e418. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020418.PMCID: PMC532388 Modern Humans Did Not Admix with Neanderthals during Their Range Expansion into Europe Mathias Currat and Laurent Excoffier PLoS Biol. 2004 December; 2(12): e421. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020421.PMCID: PMC532389 Patterns of Intron Gain and Loss in Fungi Cydney B Nielsen, Brad Friedman, Bruce Birren, Christopher B Burge, and James E Galagan PLoS Biol. 2004 December; 2(12): e422. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020422.PMCID: PMC532390 Distinct Genomic Integration of MLV and SIV Vectors in Primate Hematopoietic Stem and Progenitor Cells Peiman Hematti, Bum-Kee Hong, Cole Ferguson, Rima Adler, Hideki Hanawa, Stephanie Sellers, Ingeborg E Holt, Craig E Eckfeldt, Yugal Sharma, Manfred Schmidt, Christof von Kalle, Derek A Persons, Eric M Billings, Catherine M Verfaillie, Arthur W Nienhuis, Tyra G Wolfsberg, Cynthia E Dunbar, and Boris Calmels PLoS Biol. 2004 December; 2(12): e423. Published online 2004 November 23. doi: 10.1371/journal.pbio.0020423.PMCID: PMC529319 Algorithmic Self-Assembly of DNA Sierpinski Triangles Paul W. K Rothemund, Nick Papadakis, and Erik Winfree PLoS Biol. 2004 December; 2(12): e424. Published online 2004 December 7. doi: 10.1371/journal.pbio.0020424.PMCID: PMC534809 A Transcriptional Profile of Aging in the Human Kidney Graham E. J Rodwell, Rebecca Sonu, Jacob M Zahn, James Lund, Julie Wilhelmy, Lingli Wang, Wenzhong Xiao, Michael Mindrinos, Emily Crane, Eran Segal, Bryan D Myers, James D Brooks, Ronald W Davis, John Higgins, Art B Owen, and Stuart K Kim PLoS Biol. 2004 December; 2(12): e427. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020427.PMCID: PMC532391 Drosophila Spastin Regulates Synaptic Microtubule Networks and Is Required for Normal Motor Function Nina Tang Sherwood, Qi Sun, Mingshan Xue, Bing Zhang, and Kai Zinn PLoS Biol. 2004 December; 2(12): e429. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020429.PMCID: PMC532392 Replication of Norovirus in Cell Culture Reveals a Tropism for Dendritic Cells and Macrophages Christiane E Wobus, Stephanie M Karst, Larissa B Thackray, Kyeong-Ok Chang, Stanislav V Sosnovtsev, Gaël Belliot, Anne Krug, Jason M Mackenzie, Kim Y Green, and Herbert W. Virgin, IV PLoS Biol. 2004 December; 2(12): e432. Published online 2004 November 30. doi: 10.1371/journal.pbio.0020432.PMCID: PMC532393 Phylogeography and Genetic Ancestry of Tigers (Panthera tigris) Shu-Jin Luo, Jae-Heup Kim, Warren E Johnson, Joelle van der Walt, Janice Martenson, Naoya Yuhki, Dale G Miquelle, Olga Uphyrkina, John M Goodrich, Howard B Quigley, Ronald Tilson, Gerald Brady, Paolo Martelli, Vellayan Subramaniam, Charles McDougal, Sun Hean, Shi-Qiang Huang, Wenshi Pan, Ullas K Karanth, Melvin Sunquist, James L. D Smith, and Stephen J O'Brien PLoS Biol. 2004 December; 2(12): e442. Published online 2004 December 7. doi: 10.1371/journal.pbio.0020442.PMCID: PMC534810 |