Respiratory Mechanics and Pleural Effusion - Full Text View

Sponsored by:	Policlinico Hospital
Information provided by:	Policlinico Hospital
ClinicalTrials.gov Identifier:	NCT00258518

Purpose

The investigators aim to compare the respiratory mechanics in acute lung injury (ALI)/acute respiratory diseases syndrome (ARDS) patients with and without pleural effusion.

Condition	Intervention
Critically Ill	Procedure: mechanical ventilation

MedlinePlus related topics: CT Scans

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Diagnostic, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Official Title:	Estimation of Respiratory Mechanics (Respiratory System, Chest Wall and Lung Elastance) and Pleural Effusion at the Bedside With CT Scan.

Further study details as provided by Policlinico Hospital:

Primary Outcome Measures:

Role of pleural effusion and respiratory mechanics [ Time Frame: 1 hour ] [ Designated as safety issue: No ]

Estimated Enrollment:	20
Study Start Date:	November 2005
Estimated Study Completion Date:	March 2009
Estimated Primary Completion Date:	March 2009 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
1: Experimental ALI/ARDS patients	Procedure: mechanical ventilation evaluation of pleural effusion and respiratory mechanics, CT scan

Detailed Description:

In ALI/ARDS we evaluated the respiratory mechanics (respiratory system, chest wall and lung elastance) at the bedside while pleural effusion was evaluated with CT scan. Thus we will able to estimate any possible role of pleural effusion on the respiratory mechanics.

Eligibility

Ages Eligible for Study:	16 Years to 90 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

ALI/ARDS patients underwent invasive mechanical ventilation

Exclusion Criteria:

Haemodynamic instability
Chronic obstructive pulmonary disease (COPD) patients

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00258518

Contacts

Contact: Davide Chiumello, MD

390255033237

chiumello@libero.it

Locations

Italy
Policlinico Hospital	Recruiting
Milano, Italy, 20122
Contact: Davide Chiumello, MD 390255033237 chiumello@libero.it

Sponsors and Collaborators

Policlinico Hospital

Investigators

Principal Investigator:

Davide Chiumello, MD

Policlinico Hospital

More Information

Responsible Party:	Policlinico Hospital ( Davide Chiumello )
Study ID Numbers:	1500
Study First Received:	November 23, 2005
Last Updated:	August 11, 2008
ClinicalTrials.gov Identifier:	NCT00258518
Health Authority:	Italy: National Monitoring Centre for Clinical Trials - Ministry of Health

Keywords provided by Policlinico Hospital:

Critically ill patients

Study placed in the following topic categories:

Pleural Effusion
Respiratory Tract Diseases
Critical Illness
Pleural Diseases

Additional relevant MeSH terms:

Disease Attributes
Pathologic Processes

ClinicalTrials.gov processed this record on January 14, 2009