| Topic: | Diabetes (DM) |
| Title: | Pharmacy Update: Clinical Importance of Postprandial Hyperglycemia. |
| Author: | Campbell, R.K.; White, J.R.; Nomura, D. |
| Source: | Diabetes Educator. 27(5): 624-637. September-October, 2001. |
| Availability: | Available from American Association of Diabetes Educators. 100 West Monroe Street, 4th Floor, Chicago, IL 60603-1901. (312) 424-2426. |
| Abstract: | The role of elevated postprandial (after a meal) blood glucose levels in the etiology (cause) of diabetes related complications is of great concern. Interventions to manage both fasting and postprandial glucose levels are needed to reduce diabetes complications. This article helps diabetes educators understand these issues and the pharmaceuticals (drugs) available to help patients control hyperglycemia (high levels of blood glucose). One table summarizes the harmful effects of sustained hyperglycemia. Glycosylated hemoglobin (HbA1c, a measure of average blood glucose levels) measurements can be used to monitor both postprandial hyperglycemia (PPHG) as well as fasting plasma glucose (FPG) levels. Drugs discussed include insulin lispro (Humalog),, insulin aspart (Novolog), acarbose (Precose), miglitol (Glyset), repaglinide (Prandin), natiglinide (Starlix), and tolbutamide (Orinase). The authors stress that the most efficient way to manage PPHG is to prevent it rather than to try to improve glucose disposal. Health care providers now have the medications that, when used in combination with self monitoring (SMBG), diet, and exercise, can near normalize blood glucose values, both fasting and after meals. Treatment programs for all appropriate diabetes patients should be intensified to bring HbA1c levels to less than 7 percent. 2 tables. 26 references. |
| Format: | Journal Article |
| Language: | English. |
| Major Keywords: | Diabetes Mellitus. Hyperglycemia. Prevention. Oral Hypoglycemic Agents. Insulin. Drug Therapy. Drug Effects. Patient Care Management. |
| Minor Keywords: | Complications. Hypoglycemia. Administration and Dosage. Glycosylated Hemoglobin. Monitoring. SBMG. Diet Therapy. Self Care. Patient Education. Blood Glucose. Physiology. |
| Publication Number: | DMJA09948 |
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