Topic: Diabetes (DM)
Title: Noninvasive Insulin-Delivery Systems: Options and Progress to Date.
Author: Cefalu, W.T.
Source: In: Leahy, J.L. and Cefalu, W.T., eds. Insulin Therapy. Monticello, NY: Marcel Dekker, Inc. 2002. p. 245-260.
Availability: Available from Marcel Dekker, Inc. Cimarron Road, P.O. Box 5005, Monticello, NY 12701. (845) 796-1919 or (800) 228-1160. Fax (845) 796-1772. Email: custserv@dekker.com. Website: www.dekker.com. PRICE: $99.75. ISBN: 824707117.
Abstract: This chapter on noninvasive insulin-delivery systems is from a reference book that explores the pharmacokinetics of insulin and insulin programs. The book focuses on the latest blood glucose self-monitoring equipment and assessment strategies that can achieve optimal glycemic control and thus reduce the occurrence of complications including retinopathy (eye disease), neuropathy (nerve disease), nephropathy (kidney disease) and cardiovascular disease. In this chapter, the author brings readers up to date on the noninvasive insulin-delivery systems currently available and those currently under study. The author first reviews the history of insulin development, then details the search for a practical noninvasive insulin-delivery system. Topics include jet injectors, transdermal delivery by iontophoresis, low-frequency ultrasound, transfersomes, intranasal delivery, oral insulin, and pulmonary delivery. The author concludes that although research studies are still active, the evidence to date suggests that pulmonary insulin delivery (inhaled) may offer the potential to improve compliance and thereby help reduce the number of complications associated with diabetes. 2 figures. 2 tables. 57 references.

Format: Book Chapter
Language: English.
Major Keywords: Diabetes Mellitus. Patient Care Management. Type 1 Diabetes. Intensive Diabetes Management. Insulin Administration. Drug Therapy.
Minor Keywords: Equipment and Supplies. Insulin. History of Medicine. Patient Compliance. Insulin Infusion Systems. Nasal Insulin.
Publication Number: DMBK11681
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