| Topic: | Diabetes (DM) |
| Title: | Insulin Therapy and Hypoglycemia. |
| Author: | McCall, A.L. |
| Source: | In: Leahy, J.L. and Cefalu, W.T., eds. Insulin Therapy. Monticello, NY: Marcel Dekker, Inc. 2002. p. 193-222. |
| Availability: | Available from Marcel Dekker, Inc. Cimarron Road, P.O. Box 5005, Monticello, NY 12701. (845) 796-1919 or (800) 228-1160. Fax (845) 796-1772. Email: custserv@dekker.com. Website: www.dekker.com. PRICE: $99.75. ISBN: 824707117. |
| Abstract: | Those wishing to decrease the risk of microvascular complications of diabetes through tight glycemic (blood glucose) control inevitably face an increased risk of hypoglycemia (low blood glucose levels), often without warning symptoms and potentially with severe consequences. This chapter on insulin therapy and hypoglycemia is from a reference book that explores the pharmacokinetics of insulin and insulin programs. The book focuses on the latest blood glucose self-monitoring equipment and assessment strategies that can achieve optimal glycemic control and thus reduce the occurrence of complications including retinopathy (eye disease), neuropathy (nerve disease), nephropathy (kidney disease) and cardiovascular disease. In this chapter, the author discusses the importance of hypoglycemia in type 1 diabetes mellitus, the Diabetes Control and Complications Trial (DCCT), recognizing hypoglycemia and hypoglycemia unawareness, brain vulnerability to hypoglycemia, hypoglycemia and sudden death, hypoglycemia in type 2 diabetes mellitus, hypoglycemia and the elderly, reversible hypoglycemia disorders, managing patients with hypoglycemia on insulin therapy, treatment of hypoglycemia, monitoring diabetes to adjust insulin therapy, and insulin therapy regimens and hypoglycemia. The author concludes that modern insulin therapy is tailored toward avoidance of hypoglycemia. Insulin-therapy strategies are recommended that mimic physiological insulin secretion using a basal-bolus approach. This is accomplished partly through use of insulin preparations that more accurately mimic the way beta cells secrete insulin. 7 figures. 11 tables. 67 references. |
| Format: | Book Chapter |
| Language: | English. |
| Major Keywords: | Diabetes Mellitus. Patient Care Management. Type 1 Diabetes. Intensive Diabetes Management. Insulin. Drug Therapy. Hypoglycemia. Complications. |
| Minor Keywords: | Administration and Dosage. Blood Glucose. Patient Education. Monitoring. Risk Factors. Type 2 Diabetes. |
| Publication Number: | DMBK11679 |
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