| Topic: | Diabetes (DM) |
| Title: | Oral Agents. |
| Author: | Edelman, S.V.; Henry, R.R. |
| Source: | In: Edelman, S.V. and Henry, R.R. Diagnosis and Management of Type 2 Diabetes. Caddo, OK: Professional Communications, Inc. 2002. p. 69-120. |
| Availability: | Available from Professional Communications, Inc., Fulfillment Center, PO Box 10, Caddo, OK 74729-0010. (800)337-9838. Fax (580)367-9989. E-mail: profcomm@netcommander.com. ISBN: 1884735754. PRICE: $21.95, plus shipping and handling. |
| Abstract: | This chapter on the use of oral hypoglycemic agents is from a handbook for primary care providers that offers a concise overview of the diagnosis and management of type 2 diabetes. The majority of patients with type 2 diabetes have less than ideal metabolic control despite the medical community's understanding of the underlying pathophysiologic mechanisms of hyperglycemia (high blood glucose) and the availability of a wide variety of new treatment options. The authors contend that failure to achieve glycemic (blood glucose) goals is related in part to a misconception by patients and caregivers that type 2 diabetes is a mild disease, and not as serious as type 1 diabetes. Drug therapy with oral antidiabetes agents is required when dietary modification and exercise therapy do not result in normalization or near normalization of metabolic abnormalities. Topics include the pathophysiologic basis of pharmacologic therapy, the importance of controlling postprandial (after a meal) hyperglycemia, intensive therapy in type 2 diabetes, diabetes prevention study results, oral antidiabetes agents, thiazolidinediones (including rosiglitazone, pioglitazone), metformin (Glucophage), alpha-glucosidase inhibitors, sulfonylureas, meglitinides, monotherapy with oral antidiabetes agents, combination therapy with oral antidiabetes agents, taking patients with type 2 diabetes off insulin, and drugs under development. 5 figures. 4 tables. 31 references. |
| Format: | Book Chapter |
| Language: | English. |
| Major Keywords: | Diabetes Mellitus. Type 2 Diabetes. Drug Therapy. Patient Care Management. Oral Hypoglycemic Agents. |
| Minor Keywords: | Delivery of Health Care. Administration and Dosage. Drug Effects. Insulin. Intensive Diabetes Management. Prevention. |
| Publication Number: | DMBK10584 |
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