| Abstract: |
This article is the second in a series of four articles about presentations at the World Congress on the insulin resistance syndrome (IRS), reviewing the relationship between insulin resistance and nonalcoholic fatty liver disease (NAFLD) and aspects of insulin resistance in children and adolescents. Topics include diagnostic approaches to NAFLD, the increases in hepatic free cholesterol and lipid peroxidation in NAFLD, the evaluation and management of NAFLD, tests used to diagnose and monitor liver function, management approaches, the avoidance of alcohol and drugs, correction of underlying risk factors, the problem of liver complications arising after bariatric surgery in obese patients, drug therapy for diabetes that may affect NAFLD, cardiovascular disease risk factors, diagnosing insulin resistance in childhood and adolescence, the incidence of metabolic syndrome, the impact of parents with insulin resistance on the incidence of metabolic syndrome in their children, the fetal origins of IRS, long-term complications of IRS, type 2 diabetes in youth, the spectrum of insulin resistance among obese children, nonalcoholic steatohepatitis (NASH) in children and adolescents, and insulin sensitivity changes during puberty. 53 references. |