Topic: Diabetes (DM)
Title: Meglitinides.
Author: Patel, A.
Source: In: Patel, A. Diabetes in Focus. 2nd ed. Lewisville, TX: Pharmaceutical Press. 2003. p. 127-131.
Availability: Available from Pharmaceutical Press. c/o JAMCO Distribution, 1401 Lakeway Drive, Lewisville, TX 75057. (800) 538-1287. (972) 353-1303. E-mail: tstockstrom@majors.com or athompson@majors.com. Website: www.pharmpress.org. PRICE: L29.95. ISBN: 853695059.
Abstract: Diabetes mellitus is a common chronic disorder and represents a serious health care challenge. The prevalence of diabetes is increasing worldwide and considerable progress has been made in the understanding of diabetes management. This chapter on drug therapy with meglitinides (a new chemical class of insulin secretagogue drugs) is from a textbook that details the practical pharmaceutical care that pharmacists can provide for people with diabetes. In this chapter, the author reviews the use of two meglitinide analogues, nateglinide and repaglinide, currently licensed in the United Kingdom for use in the management of type 2 diabetes. Nateglinide is licensed for use only in combination with metformin, whereas repaglinide may be used either as monotherapy or in combination with metformin. Topics include mechanism of action, pharmacokinetics, dosage, adverse effects (hypoglycemia, weight gain), drug interactions, and preparations. 1 figure. 4 references.

Format: Book Chapter
Language: English.
Major Keywords: Diabetes Mellitus. Patient Care Management. Blood Glucose. Hyperglycemia. Meglitinides. Drug Therapy. Drug Effects. Drugs.
Minor Keywords: Oral Hypoglycemic Agents. Pharmacists. Patient Care Team. Administration and Dosage. Pharmacology. Metformin. Repaglinide.
Publication Number: DMBK11705
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