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Science News about Depression

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Depression Gene May Weaken Mood-Regulating Circuit
May 9, 2005 • Press Release
A brain scan study suggests that a suspect gene may increase susceptibility to anxiety and depression by weakening a circuit for processing negative emotion.
Actor-Patients´ Requests for Medications Boost Prescribing for Depression
April 27, 2005 • Press Release
Critics of direct-to-consumer marketing fear the advertisements lead to over-prescribing. Proponents believe they can serve a useful educational function.
Rat Brain’s Executive Hub Quells Alarm Center if Stress is Controllable
February 11, 2005 • Press Release
Treatments for mood and anxiety disorders are thought to work, in part, by helping patients control the stresses in their lives. A new study in rats by National Institutes of Health (NIH) grantees provides insight into the brain mechanisms likely involved.
Mutant Gene Linked to Treatment-Resistant Depression
December 13, 2004 • Science Update
A mutant gene that starves the brain of serotonin, a mood-regulating chemical messenger, has been discovered and found to be 10 times more prevalent in depressed patients than in control subjects, report researchers funded by the National Institutes of Health’s National Institute of Mental Health (NIMH) and National Heart Lung and Blood Institute (NHLBI).
Combination Treatment Most Effective in Adolescents with Depression
August 17, 2004 • Press Release
A clinical trial of 439 adolescents with major depression has found a combination of medication and psychotherapy to be the most effective treatment.
Depression Traced to Overactive Brain Circuit
August 2, 2004 • Press Release
A brain imaging study by the NIH’s National Institute of Mental Health (NIMH) has found that an emotion-regulating brain circuit is overactive in people prone to depression—even when they are not depressed.
“Care Managers” Help Depressed Elderly Reduce Suicidal Thoughts
March 2, 2004 • Press Release
An intervention that includes staffing doctors' offices with depression care managers helps depressed elderly patients reduce suicidal thoughts, a study funded by NIMH has found. Martha Bruce, Ph.D., Cornell University, Charles Reynolds, III, M.D., University of Pittsburgh, and colleagues report on the outcome of the intervention in three major Eastern U.S. metropolitan areas.
“Care Managers” Help Depressed Elderly Reduce Suicidal Thoughts
March 2, 2004 • Press Release
An intervention that includes staffing doctors’ offices with depression care managers helps depressed elderly patients reduce suicidal thoughts, a study funded by NIH’s National Institute of Mental Health (NIMH) has found.
Mental Illness Genetics Among Science’s Top “Breakthroughs“ for 2003
December 22, 2003 • Press Release
Research on the genetics of mental illness, most of it NIMH-funded and much of it in the Institute’s own laboratories, was named the #2 scientific "breakthrough of the year" by Science magazine in its December l9, 2003, issue.
Creation of New Neurons Critical to Antidepressant Action in Mice
August 7, 2003 • Press Release
Blocking the formation of neurons in the hippocampus blocks the behavioral effects of antidepressants in mice, say researchers funded by the National Institutes of Health (NIH).
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