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News from 2007

Family-centered Intervention Effectively Reduces Risky Behavior Among Hispanic Youth
December 20, 2007 · Science Update · A family-centered program that improves parent-child dynamics and family functioning is more effective at discouraging Hispanic youth from engaging in risky behavior than programs that target specific behaviors.
Study Aims to Develop First Medications for Fragile-X Syndrome, Leading Inherited Cause of Mental Retardation
December 20, 2007 · Science Update · A new NIMH grant is enabling scientists to begin testing safety and effectiveness of potential medications for fragile-X syndrome, the most common inherited form of mental retardation. No effective medications are available for the disorder. The animal studies currently underway are designed to lay the groundwork for the first human clinical trials in subsequent phases of the research.
IQ Boost From Breast Milk Linked to Gene-Environment Interaction
December 17, 2007 · Science Update · A new study shows that the intellectual boost associated with breast milk is only attained if a child has inherited one of two versions of a specific gene. The NIMH funded research is among the first to provide evidence of a specific genetic-environment interaction involved in complex mental functioning.
Schizophrenia-Related Gene Linked to Imbalance in Dopamine Pathways
December 17, 2007 · Science Update · Forms of a gene known to increase risk for schizophrenia may create an imbalance in brain pathways for dopamine, suggests a recent study by NIMH scientists. The findings could help explain how this key chemical messenger goes awry in the disorder, which affects about one percent of adults.
Behavioral Therapy Effectively Treats Children with Social Phobia
December 17, 2007 · Science Update · A behavioral therapy designed to treat children diagnosed with social phobia helped them overcome more of their symptoms than the antidepressant fluoxetine (Prozac).
Hurricane Katrina Survivors Lack Access to Mental Health Services
December 17, 2007 · Science Update · The majority of Hurricane Katrina survivors who developed mental disorders after the disaster are not receiving the mental health services they need, and many who were receiving mental health care prior to the hurricane were not able to continue with treatment.
Depression’s Flip Side Shares its Circuitry
December 14, 2007 · Science Update · Humans tend to be overly optimistic about the future, sometimes underestimating risks and making unrealistic plans, notes NIMH grantee Elizabeth Phelps, Ph.D., New York University. Yet “a moderate optimistic illusion” appears to be essential for maintaining motivation and good mental health
Behavioral Program May Stabilize Stress Hormone Patterns in Foster Children
November 30, 2007 · Science Update · An intervention designed to enhance family interaction and improve foster parenting skills may benefit young foster children who had experienced extreme neglect or maltreatment in early life.
Depression Linked to Bone-Thinning in Premenopausal Women
November 26, 2007 · Press Release · Premenopausal women with even mild depression have less bone mass than do their nondepressed peers, a study funded in part by NIMH.
Brain Matures a Few Years Late in ADHD, But Follows Normal Pattern
November 12, 2007 · Press Release · In youth with attention deficit hyperactivity disorder (ADHD), the brain matures in a normal pattern but is delayed three years in some regions, on average, compared to youth without the disorder.
Researchers Suggest Updating Criteria for HIV-associated Neurocognitive Disorders
November 8, 2007 · Science Update · After 10 years since the introduction of highly active antiretroviral therapy (HAART), the criteria for classifying HIV-related neurocognitive disorders may need to be revised and updated.
Preschoolers with Three or More Coexisting Disorders Show No Response to ADHD Medication Treatment
November 5, 2007 · Press Release · Preschoolers who are diagnosed with ADHD are not likely to respond to treatment with the stimulant methylphenidate, regardless of dosage, if they also have three or more coexisting disorders.
Memory-sustaining Enzyme May Help Treat PTSD, Cognitive Decline
November 2, 2007 · Science Update · Chemically blocking an enzyme in a specific area in the brain’s cortex, or outer mantle, erased a long-term memory of an aversive event that rats had learned, a study funded in part by NIMH has found.
Internet-based PTSD Therapy May Help Overcome Barriers to Care
November 1, 2007 · Science Update · NIMH-funded researchers recently completed a pilot study showing that an Internet-based, self-managed cognitive behavioral therapy (CBT) can help reduce symptoms of post-traumatic stress disorder (PTSD) and depression, with effects that last after treatment has ended. This study supports further development of PTSD therapies that focus on self-management and innovative methods of providing care to large numbers of people who do not have access to mental health care or who may be reluctant to seek care due to stigma.
NIH Funds New Program to Investigate Causes and Treatment of Autism
October 30, 2007 · Science Update · The National Institutes of Health will intensify its efforts to find the causes of autism and identify new treatments for the disorder, through a new research program. The Autism Centers of Excellence (ACE) program represents a consolidation of two existing programs, the Studies to Advance Autism Research and Treatment (STAART) and Collaborative Programs of Excellence in Autism (CPEA) programs into a single research effort.
Behavioral Intervention Normalizes Stress-related Hormone in High-Risk Kids
October 24, 2007 · Science Update · A family-based behavioral intervention that helps prevent social and behavior problems in high-risk preschoolers also may help normalize their cortisol levels when they anticipate stressful situations, results of a new NIMH study suggest.
Stress: Brain Yields Clues About Why Some Succumb While Others Prevail
October 18, 2007 · Press Release · Results of a new study may one day help scientists learn how to enhance a naturally occurring mechanism in the brain that promotes resilience to psychological stress. Researchers funded by NIMH found that, in a mouse model, the ability to adapt to stress is driven by a distinctly different molecular mechanism than is the tendency to be overwhelmed by stress.
How Schizophrenia Develops: Major Clues Discovered
October 17, 2007 · Press Release · Schizophrenia may occur, in part, because of a problem in an intermittent on/off switch for a gene involved in making a key chemical messenger in the brain, scientists have found in a study of human brain tissue.
New Social Neuroscience Grants to Help Unravel Autism, Anxiety Disorders
October 10, 2007 · Science Update · How genes and the environment shape the brain circuitry underlying social behavior is among the questions being addressed by three newly NIMH-funded studies.
Bipolar Disorder Phenome Database May Aid Search for Related Genes
October 2, 2007 · Science Update · Early findings from the recently launched Bipolar Disorder Phenome Database were published in the August 2007 issue of the American Journal of Psychiatry.
Depressed Adolescents Respond Best to Combination Treatment
October 1, 2007 · Press Release · A combination of psychotherapy and antidepressant medication appears to be the most effective treatment for adolescents with major depressive disorder—more than medication alone or psychotherapy alone.
Mental Disorders Account for Large Percentage of Adult Role Disability
October 1, 2007 · Science Update · An NIMH-funded study finds that more than half of U.S. adults have a mental or physical condition that prevents them from working or conducting their usual duties (e.g., role disability) for several days each year, and a large portion of those days can be attributed to mental disorders.
Scientists May Have Found Long-Pursued Binding Site for Antidepressants
September 28, 2007 · Science Update · NIMH-funded scientists have a major new clue as to where the long-pursued binding site for commonly used antidepressants – potentially the site that triggers the medications’ effects – may be on brain cells. The finding could lead to better medications for depression, but also has important implications for other mental illnesses because it addresses a biological flaw that a number of them share.
Genes Linked to Suicidal Thinking During Antidepressant Treatment
September 27, 2007 · Press Release · Specific variations in two genes are linked to suicidal thinking that sometimes occurs in people taking the most commonly prescribed class of antidepressants, according to a large study led by scientists at NIMH. Depending on the particular mix inherited, these versions increased the likelihood of such thoughts from 2- to15-fold, the study found.
Workplace Depression Screening, Outreach and Enhanced Treatment Improves Productivity, Lowers Employer Costs
September 26, 2007 · Press Release · Enhanced and systematic efforts to identify and treat depression in the workplace significantly improves employee health and productivity, likely leading to lower costs overall for the employer, according to a study published September 26, 2007, in the Journal of the American Medical Association.
New Collaboration Evaluates Effectiveness of Mental Illness Educational Project
September 19, 2007 · Science Update · Two new grants funded by NIMH will examine the effectiveness of educational materials designed to teach young people about mental illnesses and reduce the stigma associated with them.
Newly Funded Center Dedicated to Mental Health Research for Asian Americans
September 19, 2007 · Science Update · A new, five-year, NIMH-funded project will establish a national center to study mental health issues affecting Asian Americans.
Drops in SSRI prescription rates may coincide with increases in youth suicides
September 19, 2007 · Science Update · A 2004 spike in suicide rates may have coincided with a drop in antidepressant prescriptions for youth, following warnings from U.S. and European regulatory agencies that the medications might trigger suicidal thoughts.
Family Involvement and Focused Intervention May be Key to Helping Teens with Bulimia
September 17, 2007 · Science Update · Family-based treatment for adolescent bulimia nervosa (FBT-BN) is more effective than an individual-based therapy called supportive psychotherapy (SPT) in helping teens overcome bulimia according to an NIMH-funded study.
Manic Phase of Bipolar Disorder Benefits from Breast Cancer Medication
September 12, 2007 · Press Release · The medication tamoxifen, best known as a treatment for breast cancer, dramatically reduces symptoms of the manic phase of bipolar disorder more quickly than many standard medications for the mental illness, a new study shows.
NIMH Funds Additional New Research on Autism
September 11, 2007 · Science Update · NIMH is funding several new grants that will further our understanding of autism spectrum disorder, which is marked by a pervasive impairment in communicating, expressing emotion, and relating to others socially.
Global Survey Reveals Significant Gap in Meeting World's Mental Health Care Needs
September 6, 2007 · Press Release · Mental disorders rank among the top ten illnesses causing disability—more than 37 percent worldwide—with depression being the leading cause of disability among people ages 15 and older, according to the Global Burden of Disease and Risk Factors published in 2006.
New Research to Help Youth with Mental Disorders Transition to Adulthood
September 5, 2007 · Science Update · As young people with mental health disorders transition from adolescence to adulthood, they frequently face new and difficult challenges such as the loss of state-issued benefits like Medicaid and foster care, or loss of family-based insurance coverage. Unfortunately, many are not prepared for the abrupt transition and may not be able to effectively manage their disorder on their own.
Rates of Bipolar Diagnosis in Youth Rapidly Climbing, Treatment Patterns Similar to Adults
September 3, 2007 · Press Release · The number of visits to a doctor's office that resulted in a diagnosis of bipolar disorder in children and adolescents has increased by 40 times over the last decade, reported researchers funded in part by the National Institutes of Health (NIH).
Studies Refine Understanding of Treatments for Bipolar Disorder
September 1, 2007 · Science Update · Two new studies provide additional details on best practices for treating people with bipolar disorder, a sometimes debilitating illness marked by severe mood swings between depression and mania. The two studies are part of the NIMH-funded Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
Bipolar Youth Show Distinct Pattern of Brain Development
August 28, 2007 · Science Update · The first picturess of the brain changing before-and-after the onset of pediatric bipolar disorder reveal a distinct pattern of development, when compared to that seen in healthy youth or in childhood onset schizophrenia.
Suspect Schizophrenia Genes Act Together to Thwart Working Memory
August 28, 2007 · Science Update · Two gene variants implicated in schizophrenia interact to degrade the brain's ability to process information, NIMH researchers have discovered. The interaction impaired working memory — retaining information from moment to moment. Such thinking problems are a hallmark of this severe mental illness that affects about one percent of the population.
Unpleasant Words Trigger Strong Startle Response in People with Borderline Personality Disorder
August 22, 2007 · Science Update · Adults with borderline personality disorder (BPD) showed excessive emotional reactions when looking at words with unpleasant meanings compared to healthy people during an emotionally stimulating task, according to NIMH-funded researchers. They also found that people with more severe BPD showed a greater difference in emotional responding compared to people with less severe BPD.
Gene Triggers Obsessive Compulsive Disorder-Like Syndrome in Mice
August 22, 2007 · Press Release · Using genetic engineering, researchers have created an obsessive-compulsive disorder (OCD) - like set of behaviors in mice and reversed them with antidepressants and genetic targeting of a key brain circuit. The study, by NIH-funded researchers, suggests new strategies for treating the disorder.
Behavioral Interventions Effective for Preschoolers with ADHD
August 15, 2007 · Science Update · Two types of early interventions designed to reduce symptoms of attention deficit-hyperactivity disorder (ADHD) in preschoolers may be effective alternatives or additions to medication treatment, according to a recent NIMH-funded study.
New Studies Search for Clues to Mental Illness in Gatekeepers of Gene Expression
August 10, 2007 · Science Update · What goes awry in the brain to cause mental illness may ultimately be traced to glitches in genes - but not necessarily the parts of genes commonly suspected. Rather than the areas of genes that code for proteins, the secrets may be hidden in mysterious short sequences of genetic material called microRNAs.
Half of Children With Autism May be Diagnosable Soon After Their First Birthday
August 10, 2007 · Science Update · About half of children with autism spectrum disorders (ASD) can be diagnosed soon after their first birthday; others with the disorder may appear to develop normally until that age and then falter or regress during their second year, NIMH-funded researchers have discovered.
Gene Predicts Better Outcome as Cortex Normalizes in Teens with ADHD
August 6, 2007 · Science Update · Brain areas that control attention were thinnest in children with attention deficit hyperactivity disorder (ADHD) who carried a particular version of a gene in a study by NIMH.
Parents' Diagnoses Help to Distinguish Childhood Bipolar Disorder from Severe Mood Dysregulation
August 6, 2007 · Science Update · The parents of children who have bipolar disorder are more likely to have bipolar disorder themselves than the parents of children who have severe mood dysregulation (SMD). This finding challenges the notion of some research that suggests SMD is a type of more broadly defined childhood bipolar disorder.
New Technique Pinpoints Crossroads of Depression in Rat Brain
August 2, 2007 · Science Update · NIMH-funded scientists have developed a new high-speed technique for imaging brain activity and used it to pinpoint a circuit signal in rats that may be at the crossroads of depression.
Success or Failure of Antidepressant Citalopram Predicted by Gene Variation
August 1, 2007 · Press Release · A variation in a gene called GRIK4 appears to make people with depression more likely to respond to the medication citalopram (Celexa) than are people without the variation, a study by NIMH has found.
Faster-Acting Antidepressants Closer to Becoming a Reality
July 24, 2007 · Press Release · A new study has revealed more about how the medication ketamine, when used experimentally for depression, relieves symptoms of the disorder in hours instead of the weeks or months it takes for current antidepressants to work.
Improvement Following ADHD Treatment Sustained in Most Children
July 20, 2007 · Press Release · Most children treated in a variety of ways for attention deficit hyperactivity disorder (ADHD) showed sustained improvement after three years in a major follow-up study funded by NIMH.
New Research to Study Program that Improves Police Interactions with Mentally Ill
July 12, 2007 · Science Update · A new grant funded by NIMH will examine the effectiveness and utility of a program designed to improve police interactions with people who have mental disorders.
New Insights on how Mental Health is Influenced by Culture and Immigration Status
July 11, 2007 · Science Update · A special issue of Research in Human Development published in June 2007, examines current trends in prevalence and risk factors for mental disorders across the lifespan in diverse U.S. minority populations.
Study Offers Glimpse of Molecules That Keep Memories Alive
July 2, 2007 · Science Update · Working memory is a kind of temporary-storage system in the brain. Unlike long-term memory, it stores disposable information we must keep in mind only transiently, for tasks at hand. But how?
Violence in Schizophrenia Patients More Likely Among Those with Childhood Conduct Problems
July 2, 2007 · Press Release · Some people with schizophrenia who become violent may do so for reasons unrelated to their current illness, according to a new study analyzing data from the Clinical Antipsychotic Trials for Intervention Effectiveness (CATIE).
New Study Will Examine Effects of Excluding Anti-anxiety Medications in Medicare Part D Coverage
June 22, 2007 · Science Update · A new research grant funded by NIMH will examine the costs and benefits of excluding a commonly prescribed class of anti-anxiety medications—benzodiazepines—from coverage in the new Medicare Part D program.
Male Veterans Have Double the Suicide Rate of Civilians
June 12, 2007 · Science Update · Male veterans in the general U.S. population are twice as likely as their civilian peers to die by suicide, a large study shows.
Gene Variants Linked to Suicidal Thoughts in Some Men Starting Antidepressant Treatment
June 7, 2007 · Science Update · Some men who experience suicidal thoughts and behaviors after they first start taking antidepressant medications may be genetically predisposed to do so, according to the latest results from the NIMH-funded Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study.
Antipsychotic Medications for Schizophrenia on Equal Footing in Improving Patients’ Thinking Skills
June 4, 2007 · Science Update · Patients with schizophrenia taking antipsychotic medications experience a small improvement in thinking and reasoning skills (neurocognition), but no one medication appears to be better than the others in improving these skills during the first two crucial months of treatment, according to the latest results from the NIMH-funded Clinical Antipsychotic Trials for Intervention Effectiveness (CATIE).
NIMH Funds Research for Early Intervention in Childhood Bipolar Disorder
June 4, 2007 · Science Update · NIMH recently approved funding to test the effectiveness of an early intervention in children at high risk for developing bipolar disorder.
Genetic Roots of Bipolar Disorder Revealed by First Genome-Wide Study of Illness
May 8, 2007 · Press Release · The likelihood of developing bipolar disorder depends in part on the combined, small effects of variations in many different genes in the brain, none of which is powerful enough to cause the disease by itself, a new study shows.
Bipolar Spectrum Disorder May Be Underrecognized and Improperly Treated
May 7, 2007 · Press Release · A new study supports earlier estimates of the prevalence of bipolar disorder in the U.S. population, and suggests the illness may be more accurately characterized as a spectrum disorder.
Cell Networking Keeps Brain’s Master Clock Ticking
May 4, 2007 · Science Update · Each day, a master clock in the brain synchronizes the timing of lesser clocks in cells throughout the body to the rising and setting of the sun, regulating such daily rhythms as sleep, body temperature, eating, and activity. Scientists funded in part by the National Institute of Mental Health have now discovered that the secret to this master clock’s robust time-keeping ability lies in the unique way its cells work together.
In Second Try to Treat Depression, Cognitive Therapy Generally As Effective As Medication
May 1, 2007 · Science Update · Switching to or adding cognitive therapy (CT) after a first unsuccessful attempt at treating depression with an antidepressant medication is generally as effective as switching to or adding another medication, but remission may take longer to achieve.
Cortex Area Thinner in Youth with Alzheimer’s-Related Gene
April 24, 2007 · Press Release · A part of the brain first affected by Alzheimer’s disease is thinner in youth with a risk gene for the disorder, a brain imaging study by researchers at the National Institute of Mental Health (NIMH), one of the National Institutes of Health (NIH), has found.
Benefits of Antidepressants May Outweigh Risks for Kids
April 17, 2007 · Science Update · The benefits of antidepressant medications likely outweigh their risks to children and adolescents with major depression and anxiety disorders, according to a new comprehensive review of pediatric trials conducted between 1988 and 2006. The study, partially funded by NIMH, was published in the April 18, 2007, issue of the Journal of the American Medical Association.
Gene Knockout Unleashes Manic Mouse
April 5, 2007 · Science Update · Mice engineered to lack a specific gene showed behaviors similar to human mania in a study funded in part by NIMH; they were hyperactive, slept less, appeared less depressed and anxious, and craved sugar, cocaine and pleasure stimulation.
Scientists Switch Neurons On and Off Using Light
April 5, 2007 · Science Update · Researchers have invented a genetically-engineered way to turn the electrical impulses of brain cells on and off with pulses of blue and yellow light — in synch with the split-second pace of real time neuronal activity.
Intensive Psychotherapy More Effective Than Brief Therapy for Treating Bipolar Depression
April 2, 2007 · Press Release · Patients taking medications to treat bipolar disorder are more likely to get well faster and stay well if they receive intensive psychotherapy, according to results from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD), funded by NIMH.
Study Sheds Light on Medication Treatment Options for Bipolar Disorder
March 28, 2007 · Press Release · For depressed people with bipolar disorder who are taking a mood stabilizer, adding an antidepressant medication is no more effective than a placebo (sugar pill), according to results published online on March 28, 2007 in the New England Journal of Medicine.
Tiny, Spontaneous Gene Mutations May Boost Autism Risk
March 15, 2007 · Press Release · Tiny gene mutations, each individually rare, pose more risk for autism than had been previously thought, suggests a study funded in part by the National Institute of Mental Health, a component of the National Institutes of Health.
Adolescent Brains Show Lower Activity in Areas That Control Risky Choices
March 15, 2007 · Science Update · A new NIMH study could help explain why adolescents are so prone to make risky choices. When contemplating risky decisions, they show less activity in regions of the brain that regulate processes involved in decision-making, compared with adults.
Depression Risk Higher in Girls with Low Birth Weight
March 9, 2007 · Science Update · irls’ risk for developing depression after puberty increased significantly if they had low birth weight, in a study funded in part by NIMH.
HIV Treatment May Help Reduce Severity of Mental Impairment in Children with HIV Infection
March 7, 2007 · Science Update · During the first few years of life, children born with HIV infection are most susceptible to central nervous system (CNS) disease, and can develop impaired cognitive, language, motor and behavioral functioning.
Global Use of ADHD Medications Rises Dramatically
March 6, 2007 · Science Update · Global use of medications that treat attention deficit/hyperactivity disorder (ADHD) nearly tripled from 1993 to 2003, and spending on the drugs rose nine-fold, according to a study co-funded by NIMH and published in the March/April 2007 issue of Health Affairs.
African Americans, Black Caribbeans, and Whites Differ in Depression Risk, Treatment
March 5, 2007 · Science Update · Although black Americans are less likely than whites to have a major depressive disorder (MDD), when they do, it tends to be more chronic and severe.
Virtual-Reality Video Game Helps Link Depression to Specific Brain Area
March 1, 2007 · Science Update · Scientists are using a virtual-reality, three-dimensional video game that challenges spatial memory as a new tool for assessing the link between depression and the hippocampus, the brain’s memory hub.
New Details in Schizophrenia Treatment Trial Emerge
March 1, 2007 · Press Release · Two new studies from the Clinical Antipsychotic Trials for Intervention Effectiveness (CATIE) provide more insights into comparing treatment options, and to what extent antipsychotic medications help people with schizophrenia learn social, interpersonal and community living skills.
Weight Gain From Antipsychotics Traced to Appetite-Regulating Enzyme, Receptor
February 28, 2007 · Science Update · A likely mechanism by which antipsychotic medications trigger weight gain — with its attendant risks of heart disease, diabetes and treatment non-adherence — has been unraveled in mice by NIMH-funded scientists.
Largest-Ever Search for Autism Genes Reveals New Clues
February 18, 2007 · Press Release · The largest search for autism genes to date, funded in part by the National Institutes of Health (NIH), has implicated components of the brain’s glutamate chemical messenger system and a previously overlooked site on chromosome 11.
Common Gene Version Optimizes Thinking — but With a Possible Downside
February 9, 2007 · Press Release · Most people inherit a version of a gene that optimizes their brain’s thinking circuitry, yet also appears to increase risk for schizophrenia, a severe mental illness marked by impaired thinking, scientists at the National Institutes of Health’s (NIH) National Institute of Mental Health (NIMH) have discovered.
Study Tracks Prevalence of Eating Disorders
February 9, 2007 · Science Update · Results from a large-scale national survey suggest that binge-eating disorder is more prevalent than both anorexia nervosa and bulimia nervosa.
Half of Adults With Anxiety Disorders Had Psychiatric Diagnoses in Youth
February 7, 2007 · Science Update · About half of adults with an anxiety disorder had symptoms of some type of psychiatric illness by age 15, a NIMH-funded study shows.
Autism Research Efforts Highlighted in Biological Psychiatry Special Issue
February 6, 2007 · Science Update · The February 15, 2007 special issue of Biological Psychiatry is dedicated to recent advances in autism research, including many studies funded by the Institute.
Brain’s Reward Circuit Activity Ebbs and Flows with a Woman’s Hormonal Cycle
February 2, 2007 · Press Release · Fluctuations in sex hormone levels during women’s menstrual cycles affect the responsiveness of their brains’ reward circuitry, an imaging study at the National Institute of Mental Health (NIMH) has revealed.
Extreme Irritability: Is It Childhood Bipolar Disorder?
February 1, 2007 · Press Release · Results of a new study may help improve the diagnosis and treatment of two debilitating childhood mental disorders — pediatric bipolar disorder (BD) and a syndrome called severe mood dysregulation (SMD).
New Tests May Help Researchers Detect Genetic Basis For Autism
January 30, 2007 · Science Update · Researchers have developed a set of behavioral tests in mice that mimic the core features of autism and may prove useful in detecting a genetic basis for the deficits in social interactions and rigid thinking seen in the disorder.
Clues to Making and Breaking Memories Included in List of Year’s Top Science
January 30, 2007 · Science Update · NIMH-funded researchers were cited in Science Magazine’s December 2006 “Breakthrough of the Year” special issue.
Gene Variant Linked to Schizophrenia
January 23, 2007 · Science Update · A gene implicated in schizophrenia in adults has now also been linked to schizophrenia in children for the first time, strengthening evidence that the gene plays a role in the disease.
U.S.-born Children of Immigrants May Have Higher Risk for Mental Disorders Than Parents
January 17, 2007 · Science Update · In the first studies to examine the effects of immigration and years of residence on the mental health of Caribbean Black, Latino, and Asian populations in the United States, NIMH-funded researchers found that immigrants in general appear to have lower rates of mental disorders than their U.S.-born counterparts.
History of Childhood Abuse or Neglect Increases Risk of Major Depression
January 3, 2007 · Science Update · People who were abused or neglected as children have increased risk of major depression, which often begins in childhood and has lingering effects as they mature, according to a study funded by NIMH.
Different Families, Different Characteristics — Different Kinds of Bipolar Disorder?
January 3, 2007 · Science Update · People with bipolar disorder (BPD) tend to share similarities in certain characteristics with other members of their families, NIMH-funded researchers have shown.