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Preschoolers with Three or More Coexisting Disorders Show No Response to ADHD Medication Treatment
November 5, 2007 • Press Release
Preschoolers who are diagnosed with ADHD are not likely to respond to treatment with the stimulant methylphenidate, regardless of dosage, if they also have three or more coexisting disorders.
Memory-sustaining Enzyme May Help Treat PTSD, Cognitive Decline
November 2, 2007 • Science Update
Chemically blocking an enzyme in a specific area in the brain’s cortex, or outer mantle, erased a long-term memory of an aversive event that rats had learned, a study funded in part by NIMH has found.
Internet-based PTSD Therapy May Help Overcome Barriers to Care
November 1, 2007 • Science Update
NIMH-funded researchers recently completed a pilot study showing that an Internet-based, self-managed cognitive behavioral therapy (CBT) can help reduce symptoms of post-traumatic stress disorder (PTSD) and depression, with effects that last after treatment has ended. This study supports further development of PTSD therapies that focus on self-management and innovative methods of providing care to large numbers of people who do not have access to mental health care or who may be reluctant to seek care due to stigma.
NIH Funds New Program to Investigate Causes and Treatment of Autism
October 30, 2007 • Science Update
The National Institutes of Health will intensify its efforts to find the causes of autism and identify new treatments for the disorder, through a new research program. The Autism Centers of Excellence (ACE) program represents a consolidation of two existing programs, the Studies to Advance Autism Research and Treatment (STAART) and Collaborative Programs of Excellence in Autism (CPEA) programs into a single research effort.
Behavioral Intervention Normalizes Stress-related Hormone in High-Risk Kids
October 24, 2007 • Science Update
A family-based behavioral intervention that helps prevent social and behavior problems in high-risk preschoolers also may help normalize their cortisol levels when they anticipate stressful situations, results of a new NIMH study suggest.
Stress: Brain Yields Clues About Why Some Succumb While Others Prevail
October 18, 2007 • Press Release
Results of a new study may one day help scientists learn how to enhance a naturally occurring mechanism in the brain that promotes resilience to psychological stress. Researchers funded by NIMH found that, in a mouse model, the ability to adapt to stress is driven by a distinctly different molecular mechanism than is the tendency to be overwhelmed by stress.
National Survey Tracks Prevalence of Personality Disorders in U.S. Population
October 18, 2007 • Science Update
NIMH-funded researchers recently reported that roughly nine percent of U.S. adults have a personality disorder as defined by the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders, or DSM-IV. Many people with personality disorders were also found to have co-occurring major mental disorders.
How Schizophrenia Develops: Major Clues Discovered
October 17, 2007 • Press Release
Schizophrenia may occur, in part, because of a problem in an intermittent on/off switch for a gene involved in making a key chemical messenger in the brain, scientists have found in a study of human brain tissue.
New Social Neuroscience Grants to Help Unravel Autism, Anxiety Disorders
October 10, 2007 • Science Update
How genes and the environment shape the brain circuitry underlying social behavior is among the questions being addressed by three newly NIMH-funded studies.
Bipolar Disorder Phenome Database May Aid Search for Related Genes
October 2, 2007 • Science Update
Early findings from the recently launched Bipolar Disorder Phenome Database were published in the August 2007 issue of the American Journal of Psychiatry.
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