| | This journal provides immediate access to some articles. Commentaries The 2-Å postdoc Ben M. Dunn PMCID: PMC33373 What sugar next? Dimerization of sphingolipid
glycosyltransferases Gerrit van Meer PMCID: PMC33374 Documenting plant domestication: The consilience of biological
and archaeological approaches Bruce D. Smith PMCID: PMC33375 New views of evolution and regulation of vertebrate β-like
globin gene clusters from an orphaned gene in marsupials Ross C. Hardison PMCID: PMC33376 A new “kid” on the platelet thrombin receptor
“block”: Glycoprotein Ib–IX–V Gerald J. Roth PMCID: PMC33377 Protein acrobatics and bacterial cell polarity Debabrata RayChaudhuri, G. Scott Gordon, and Andrew Wright PMCID: PMC33378 What can you do with a bone fragment? Pat Shipman PMCID: PMC33379 Bacterial menageries inside insects Nancy A. Moran PMCID: PMC33380 Physical Sciences Applied Mathematics A numerical strategy for efficient modeling of the equatorial
wave guide Andrew J. Majda and Boualem Khouider PMCID: PMC29258 Astronomy Ancient Maya documents concerning the movements of Mars Harvey M. Bricker, Anthony F. Aveni, and Victoria R. Bricker PMCID: PMC29390 Chemistry Double-level “orthogonal” dynamic combinatorial libraries
on transition metal template Vasiliy Goral, Marina I. Nelen, Alexey V. Eliseev, and Jean-Marie Lehn PMCID: PMC29259 Engineering The origins of stability of spontaneous vesicles H. T. Jung, B. Coldren, J. A. Zasadzinski, D. J. Iampietro, and E. W. Kaler PMCID: PMC29260 Biological Sciences Anthropology From the Cover:
Evidence of termite foraging by Swartkrans early hominids Lucinda R. Backwell and Francesco d'Errico PMCID: PMC29261 The earliest archaeological maize (Zea mays L.)
from highland Mexico: New accelerator mass spectrometry dates and
their implications D. R. Piperno and K. V. Flannery PMCID: PMC29388 Archaeological evidence of teosinte domestication from
Guilá Naquitz, Oaxaca Bruce F. Benz PMCID: PMC29389 Biochemistry Dynamic regulation of the tryptophan operon: A modeling study
and comparison with experimental data Moisés Santillán and Michael C. Mackey PMCID: PMC29262 Identification of two novel transmembrane γ-carboxyglutamic
acid proteins expressed broadly in fetal and adult tissues John D. Kulman, Jeff E. Harris, Ling Xie, and Earl W. Davie PMCID: PMC29263 Interaction of the herbicide glyphosate with its target enzyme
5-enolpyruvylshikimate 3-phosphate synthase in atomic detail Ernst Schönbrunn, Susanne Eschenburg, Wendy A. Shuttleworth, John V. Schloss, Nikolaus Amrhein, Jeremy N. S. Evans, and Wolfgang Kabsch PMCID: PMC29264 From the Cover:
The reversible condensation and expansion of the
rotavirus genome Joseph B. Pesavento, Jeffrey A. Lawton, Mary K. Estes, and B. V. Venkataram Prasad PMCID: PMC29265 Role of transforming growth factor-α in von Hippel– Lindau
(VHL)−/− clear cell renal carcinoma cell proliferation: A
possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis Natalie de Paulsen, Alexander Brychzy, Marie-Christine Fournier, Richard D. Klausner, James R. Gnarra, Arnim Pause, and Stephen Lee PMCID: PMC29266 Oligonucleotide-directed peptide synthesis in a ribosome- and
ribozyme-free system Koji Tamura and Paul Schimmel PMCID: PMC29267 Visualization of a water-selective pore by electron
crystallography in vitreous ice G. Ren, V. S. Reddy, A. Cheng, P. Melnyk, and A. K. Mitra PMCID: PMC29268 Design of three-dimensional domain-swapped dimers and fibrous
oligomers Nancy L. Ogihara, Giovanna Ghirlanda, James W. Bryson, Mari Gingery, William F. DeGrado, and David Eisenberg PMCID: PMC29269 Predicting the reactivity of proteins from their sequence alone:
Kazal family of protein inhibitors of serine proteinases Stephen M. Lu, Wuyuan Lu, M. A. Qasim, Stephen Anderson, Izydor Apostol, Wojciech Ardelt, Theresa Bigler, Yi Wen Chiang, James Cook, Michael N. G. James, Ikunoshin Kato, Clyde Kelly, William Kohr, Tomoko Komiyama, Tiao-Yin Lin, Michio Ogawa, Jacek Otlewski, Soon-Jae Park, Sabiha Qasim, Michael Ranjbar, Misao Tashiro, Nicholas Warne, Harry Whatley, Anna Wieczorek, Maciej Wieczorek, Tadeusz Wilusz, Richard Wynn, Wenlei Zhang, and Michael Laskowski, Jr. PMCID: PMC29270 Uncoupling proteins 2 and 3 are highly active H+
transporters and highly nucleotide sensitive when activated by
coenzyme Q (ubiquinone) Karim S. Echtay, Edith Winkler, Karina Frischmuth, and Martin Klingenberg PMCID: PMC29271 Conserved interaction between distinct
Krüppel-associated box domains and the transcriptional intermediary factor 1 β Magnus Abrink, José A. Ortiz, Charlotta Mark, Cecilia Sanchez, Camilla Looman, Lars Hellman, Pierre Chambon, and Régine Losson PMCID: PMC29272 A 1.2-Å snapshot of the final step of bacterial cell
wall biosynthesis Wenlin Lee, Michael A. McDonough, Lakshmi P. Kotra, Zhi-Hong Li, Nicholas R. Silvaggi, Yoshifumi Takeda, Judith A. Kelly, and Shahriar Mobashery PMCID: PMC29273 From the Cover:
Design of polyzinc finger peptides with structured linkers Michael Moore, Yen Choo, and Aaron Klug PMCID: PMC29274 From the Cover:
Improved DNA binding specificity from polyzinc finger peptides by
using strings of two-finger units Michael Moore, Aaron Klug, and Yen Choo PMCID: PMC29275 Crystal structure of the Holliday junction migration motor
protein RuvB from Thermus thermophilus HB8 Kazuhiro Yamada, Naoki Kunishima, Kouta Mayanagi, Takayuki Ohnishi, Tatsuya Nishino, Hiroshi Iwasaki, Hideo Shinagawa, and Kosuke Morikawa PMCID: PMC29276 Surface-localized glycine transporters 1 and 2 function as
monomeric proteins in Xenopus oocytes Masahisa Horiuchi, Annette Nicke, Jesus Gomeza, Armaz Aschrafi, Günther Schmalzing, and Heinrich Betz PMCID: PMC29277 CoREST is an integral component of the CoREST- human histone
deacetylase complex Angie You, Jeffrey K. Tong, Christina M. Grozinger, and Stuart L. Schreiber PMCID: PMC29278 The crystal structure of the nitrogen regulation fragment of the
yeast prion protein Ure2p Timothy C. Umland, Kimberly L. Taylor, Sangkee Rhee, Reed B. Wickner, and David R. Davies PMCID: PMC29279 Crystal structure of a DEAD box protein from the hyperthermophile
Methanococcus jannaschii Randall M. Story, Hong Li, and John N. Abelson PMCID: PMC29280 Identification of two short internal ribosome entry sites
selected from libraries of random oligonucleotides Geoffrey C. Owens, Stephen A. Chappell, Vincent P. Mauro, and Gerald M. Edelman PMCID: PMC29281 Expression of sterol regulatory element-binding protein 1c
(SREBP-1c) mRNA in rat hepatoma cells requires
endogenous LXR ligands Russell A. DeBose-Boyd, Jiafu Ou, Joseph L. Goldstein, and Michael S. Brown PMCID: PMC29282 Jac1, a mitochondrial J-type chaperone, is involved in the
biogenesis of Fe/S clusters in
Saccharomyces cerevisiae Cindy Voisine, Yu C. Cheng, Maikke Ohlson, Brenda Schilke, Kevin Hoff, Helmut Beinert, Jaroslaw Marszalek, and Elizabeth A. Craig PMCID: PMC29283 Involvement of a cytosine side chain in proton transfer in the
rate-determining step of ribozyme self-cleavage I-hung Shih and Michael D. Been PMCID: PMC29284 Ash1p is a site-specific DNA-binding protein that actively
represses transcription Mary E. Maxon and Ira Herskowitz PMCID: PMC29285 Molecular cloning of a cytochrome P450 taxane 10β-hydroxylase
cDNA from Taxus and functional expression in yeast Anne Schoendorf, Christopher D. Rithner, Robert M. Williams, and Rodney B. Croteau PMCID: PMC29286 The quorum-sensing transcriptional regulator TraR requires its
cognate signaling ligand for protein folding, protease resistance,
and dimerization Jun Zhu and Stephen C. Winans PMCID: PMC29287 The surface coat of procyclic Trypanosoma brucei:
Programmed expression and proteolytic cleavage of procyclin in the
tsetse fly Alvaro Acosta-Serrano, Erik Vassella, Matthias Liniger, Christina Kunz Renggli, Reto Brun, Isabel Roditi, and Paul T. Englund PMCID: PMC29288 The E2F6 transcription factor is a component of the mammalian
Bmi1-containing polycomb complex Jeffrey M. Trimarchi, Brian Fairchild, Jessica Wen, and Jacqueline A. Lees PMCID: PMC29289 Trapping the transition state of an ATP-binding cassette
transporter: Evidence for a concerted mechanism of maltose transport Jue Chen, Susan Sharma, Florante A. Quiocho, and Amy L. Davidson PMCID: PMC29290 Transcript leader regions of two Saccharomyces
cerevisiae mRNAs contain internal ribosome entry sites that
function in living cells Wei Zhou, Gerald M. Edelman, and Vincent P. Mauro PMCID: PMC29291 Mutagenesis of the regulatory domain of
phenylalanine hydroxylase Guo-An Wang, Peide Gu, and Seymour Kaufman PMCID: PMC29292 Constitutively activated Stat3 protects fibroblasts from serum
withdrawal and UV-induced apoptosis and antagonizes the
proapoptotic effects of activated Stat1 Yuhong Shen, Geeta Devgan, James E. Darnell, Jr., and Jacqueline F. Bromberg PMCID: PMC29293 Biophysics The structure of the ultraspiracle ligand-binding domain reveals
a nuclear receptor locked in an inactive conformation Gina M. Clayton, Sew Y. Peak-Chew, Ronald M. Evans, and John W. R. Schwabe PMCID: PMC29294 Electrophysiological characterization of specific interactions
between bacterial sensory rhodopsins and their transducers G. Schmies, M. Engelhard, P. G. Wood, G. Nagel, and E. Bamberg PMCID: PMC29295 Origin of nanomechanical cantilever motion generated from
biomolecular interactions Guanghua Wu, Haifeng Ji, Karolyn Hansen, Thomas Thundat, Ram Datar, Richard Cote, Michael F. Hagan, Arup K. Chakraborty, and Arunava Majumdar PMCID: PMC29296 Forced unfolding modulated by disulfide bonds in the Ig domains
of a cell adhesion molecule Philippe Carl, Carol H. Kwok, Gavin Manderson, David W. Speicher, and Dennis E. Discher PMCID: PMC29297 Tight Asp-85–Thr-89 association during the pump switch
of bacteriorhodopsin Hideki Kandori, Yoichi Yamazaki, Yoshinori Shichida, Jan Raap, Johan Lugtenburg, Marina Belenky, and Judith Herzfeld PMCID: PMC29298 Real-time visualization of intracellular hydrodynamics in single
living cells Eric O. Potma, Wim P. de Boeij, Peter J. M. van Haastert, and Douwe A. Wiersma PMCID: PMC29299 Cell Biology Vascular tumors in livers with targeted inactivation of the von
Hippel–Lindau tumor suppressor Volker H. Haase, Jonathan N. Glickman, Merav Socolovsky, and Rudolf Jaenisch PMCID: PMC29300 Embryonic expression of the tumor-associated PAX3-FKHR fusion
protein interferes with the developmental functions of Pax3 Michael J. Anderson, G. Diane Shelton, Webster K. Cavenee, and Karen C. Arden PMCID: PMC29301 Myozenin: An α-actinin- and γ-filamin-binding protein of
skeletal muscle Z lines Fumio Takada, Douglas L. Vander Woude, Hui-Qi Tong, Terri G. Thompson, Simon C. Watkins, Louis M. Kunkel, and Alan H. Beggs PMCID: PMC29302 β-Arrestin 1 and 2 differentially regulate heptahelical
receptor signaling and trafficking Trudy A. Kohout, Fang-Tsyr Lin, Stephen J. Perry, David A. Conner, and Robert J. Lefkowitz PMCID: PMC29303 Dual modulation of cell survival and cell death by
β2-adrenergic signaling in adult mouse cardiac myocytes Wei-Zhong Zhu, Ming Zheng, Walter J. Koch, Robert J. Lefkowitz, Brian K. Kobilka, and Rui-Ping Xiao PMCID: PMC29304 Expression of scavenger receptor class B type 1 (SR-BI) promotes
microvillar channel formation and selective cholesteryl ester
transport in a heterologous reconstituted system Eve Reaven, Susan Leers-Sucheta, Ann Nomoto, and Salman Azhar PMCID: PMC29305 A TSG101/MDM2 regulatory loop modulates MDM2 degradation
and MDM2/p53 feedback control Limin Li, Jian Liao, Jürgen Ruland, Tak W. Mak, and Stanley N. Cohen PMCID: PMC29306 From the Cover:
Physical and functional association of glycolipid
N-acetyl-galactosaminyl and galactosyl transferases in the Golgi apparatus Claudio G. Giraudo, Jose L. Daniotti, and Hugo J. F. Maccioni PMCID: PMC29307 Bromination of deoxycytidine by eosinophil peroxidase: A
mechanism for mutagenesis by oxidative damage of nucleotide precursors Jeffrey P. Henderson, Jaeman Byun, Michelle V. Williams, Michael L. McCormick, William C. Parks, Lisa A. Ridnour, and Jay W. Heinecke PMCID: PMC29308 A FYVE-finger-containing protein, Rabip4, is a Rab4 effector
involved in early endosomal traffic Mireille Cormont, Muriel Mari, Antoine Galmiche, Paul Hofman, and Yannick Le Marchand-Brustel PMCID: PMC29309 Induction of oxyradicals by arsenic: Implication for mechanism
of genotoxicity Su X. Liu, Mohammad Athar, Istvan Lippai, Charles Waldren, and Tom K. Hei PMCID: PMC29310 Developmental Biology The Ath5 proneural genes function upstream of
Brn3 POU domain transcription factor genes to promote
retinal ganglion cell development Wei Liu, Zeqian Mo, and Mengqing Xiang PMCID: PMC29311 From cell death to embryo arrest: Mathematical models of human
preimplantation embryo development K. Hardy, S. Spanos, D. Becker, P. Iannelli, R. M. L. Winston, and J. Stark PMCID: PMC29312 Evolution Monophyly and extensive extinction of advanced eusocial bees:
Insights from an unexpected Eocene diversity Michael S. Engel PMCID: PMC29313 Lamprey Dlx genes and early vertebrate evolution Adam H. Neidert, Vikrant Virupannavar, Gillian W. Hooker, and James A. Langeland PMCID: PMC29314 Negative genetic correlation for adult fitness between sexes
reveals ontogenetic conflict in Drosophila Adam K. Chippindale, Jonathan R. Gibson, and William R. Rice PMCID: PMC29315 Genetics ATM-dependent expression of the insulin-like growth factor-I
receptor in a pathway regulating radiation response Shani Peretz, Ryan Jensen, Renato Baserga, and Peter M. Glazer PMCID: PMC29316 A premature-termination mutation in the Mus
musculus cyclin-dependent kinase 3 gene Xin Ye, Cihui Zhu, and J. Wade Harper PMCID: PMC29317 A single gene for lycopene cyclase, phytoene synthase, and
regulation of carotene biosynthesis in Phycomyces Nabil Arrach, Rafael Fernández-Martín, Enrique Cerdá-Olmedo, and Javier Avalos PMCID: PMC29318 Dynamic modeling of gene expression data Neal S. Holter, Amos Maritan, Marek Cieplak, Nina V. Fedoroff, and Jayanth R. Banavar PMCID: PMC29319 Eight novel families of miniature inverted repeat transposable
elements in the African malaria mosquito,
Anopheles gambiae Zhijian Tu PMCID: PMC29320 Untargeted mutation of the maternally derived mouse hypervariable
minisatellite allele in F1 mice born to irradiated
spermatozoa Ohtsura Niwa and Ryo Kominami PMCID: PMC29321 RAD50 function is essential for telomere
maintenance in Arabidopsis Maria E. Gallego and Charles I. White PMCID: PMC29322 Immunology Mitochondria in eosinophils: Functional role in apoptosis
but not respiration Kristina K. Peachman, Douglas S. Lyles, and David A. Bass PMCID: PMC29323 Differences in antigen recognition and cytolytic activity of
CD8+ and CD8− T cells that express the
same antigen-specific receptor Bryan K. Cho, Kuo-Chiang Lian, Peter Lee, Anders Brunmark, Carol McKinley, Jianzhu Chen, David M. Kranz, and Herman N. Eisen PMCID: PMC29324 Dependence of lymphopenia-induced T cell proliferation on the
abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors Qing Ge, Varada P. Rao, Bryan K. Cho, Herman N. Eisen, and Jianzhu Chen PMCID: PMC29325 The role of zinc in the binding of killer cell Ig-like receptors
to class I MHC proteins Mar Valés-Gómez, Robert A. Erskine, Matthew P. Deacon, Jack L. Strominger, and Hugh T. Reyburn PMCID: PMC29326 The role of MHC class I glycoproteins in the regulation of
induction of cell death in immunocytes by malignant melanoma cells Daniel Fishman, Brodyanski Irena, Sigal Kellman-Pressman, Michael Karas, and Shraga Segal PMCID: PMC29327 Induction of pre-B cell proliferation after de
novo synthesis of the pre-B cell receptor Jochen Hess, Annick Werner, Thomas Wirth, Fritz Melchers, Hans-Martin Jäck, and Thomas H. Winkler PMCID: PMC29328 Regulation of CD40 function by its isoforms generated through
alternative splicing Masahide Tone, Yukiko Tone, Paul J. Fairchild, Michelle Wykes, and Herman Waldmann PMCID: PMC29329 Distinct role of gp130 activation in promoting self-renewal
divisions by mitogenically stimulated murine hematopoietic stem
cells Julie Audet, Cindy L. Miller, Stefan Rose-John, James M. Piret, and Connie J. Eaves PMCID: PMC29330 Identification and modulation of a naturally processed T cell
epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65) Gerald T. Nepom, John D. Lippolis, Forest M. White, Susan Masewicz, Jarrod A. Marto, Andrew Herman, C. John Luckey, Ben Falk, Jeffrey Shabanowitz, Donald F. Hunt, Victor H. Engelhard, and Barbara S. Nepom PMCID: PMC29331 Jun N-terminal kinase 2 modulates thymocyte apoptosis and
T cell activation through c-Jun and nuclear factor of activated T
cell (NF-AT) Axel Behrens, Kanaga Sabapathy, Isabella Graef, Mike Cleary, Gerald R. Crabtree, and Erwin F. Wagner PMCID: PMC29332 A shark antibody heavy chain encoded by a nonsomatically
rearranged VDJ is preferentially expressed in early development and
is convergent with mammalian IgG Lynn L. Rumfelt, David Avila, Marilyn Diaz, Simona Bartl, E. Churchill McKinney, and Martin F. Flajnik PMCID: PMC29333 The HIV-1 regulatory proteins Tat and Rev are frequently targeted
by cytotoxic T lymphocytes derived from HIV-1-infected individuals Marylyn M. Addo, Marcus Altfeld, Eric S. Rosenberg, Robert L. Eldridge, Mary N. Philips, Kathleen Habeeb, Ashok Khatri, Christian Brander, Gregory K. Robbins, Gail P. Mazzara, Philip J. R. Goulder, Bruce D. Walker, and the HIV Controller
Study Collaboration PMCID: PMC29334 The major murine systemic lupus erythematosus susceptibility
locus, Sle1, is a cluster of functionally
related genes Laurence Morel, Kim R. Blenman, Byron P. Croker, and Edward K. Wakeland PMCID: PMC29335 Medical Sciences Anti-DNA antibodies are a major component of the intrathecal B
cell response in multiple sclerosis R. Anthony Williamson, Mark P. Burgoon, Gregory P. Owens, Omar Ghausi, Estelle Leclerc, Louise Firme, Sharon Carlson, John Corboy, Paul W. H. I. Parren, Pietro P. Sanna, Donald H. Gilden, and Dennis R. Burton PMCID: PMC29336 A human myeloma cell line suitable for the generation of
human monoclonal antibodies Abraham Karpas, Alla Dremucheva, and Barbara H. Czepulkowski PMCID: PMC29337 Platelet-mediated clumping of Plasmodium
falciparum-infected erythrocytes is a common adhesive
phenotype and is associated with severe malaria Arnab Pain, David J. P. Ferguson, Oscar Kai, Britta C. Urban, Brett Lowe, Kevin Marsh, and David J. Roberts PMCID: PMC29338 The Gln-Ala repeat transcriptional activator CA150 interacts with
huntingtin: Neuropathologic and genetic evidence for a role in
Huntington's disease pathogenesis Sébastien Holbert, Isabelle Denghien, Tamara Kiechle, Adam Rosenblatt, Cheryll Wellington, Michael R. Hayden, Russell L. Margolis, Christopher A. Ross, Jean Dausset, Robert J. Ferrante, and Christian Néri PMCID: PMC29339 p53 associates with and targets ΔNp63 into a protein
degradation pathway Edward A. Ratovitski, Meera Patturajan, Kenji Hibi, Barry Trink, Kengo Yamaguchi, and David Sidransky PMCID: PMC29340 A thrombin receptor function for platelet glycoprotein Ib–IX
unmasked by cleavage of glycoprotein V Vanitha Ramakrishnan, Francis DeGuzman, Ming Bao, Scott W. Hall, Lawrence L. Leung, and David R. Phillips PMCID: PMC29341 Luteinizing hormone-releasing hormone (LH-RH) antagonist
Cetrorelix down-regulates the mRNA expression of pituitary receptors
for LH-RH by counteracting the stimulatory effect of
endogenous LH-RH Magdolna Kovacs, Andrew V. Schally, Balazs Csernus, and Zoltan Rekasi PMCID: PMC29342 Inhibition of the visual cycle in vivo by
13-cis retinoic acid protects from light damage and
provides a mechanism for night blindness in isotretinoin therapy Paul A. Sieving, Prem Chaudhry, Mineo Kondo, Matthew Provenzano, David Wu, Thomas J. Carlson, Ronald A. Bush, and Debra A. Thompson PMCID: PMC29343 Transcriptional regulation of hepatitis B virus by nuclear
hormone receptors is a critical determinant of viral tropism Hong Tang and Alan McLachlan PMCID: PMC29344 Mechanism for fetal globin gene expression: Role of the soluble
guanylate cyclase–cGMP-dependent protein
kinase pathway Tohru Ikuta, Sabrina Ausenda, and Maria D. Cappellini PMCID: PMC29345 Integrin activation controls metastasis in human breast cancer Brunhilde Felding-Habermann, Timothy E. O'Toole, Jeffrey W. Smith, Emilia Fransvea, Zaverio M. Ruggeri, Mark H. Ginsberg, Paul E. Hughes, Nisar Pampori, Sanford J. Shattil, Alan Saven, and Barbara M. Mueller PMCID: PMC29346 p53 Accumulation, defective cell proliferation, and early
embryonic lethality in mice lacking tsg101 Jürgen Ruland, Christian Sirard, Andrew Elia, David MacPherson, Andrew Wakeham, Limin Li, José Luis de la Pompa, Stanley N. Cohen, and Tak W. Mak PMCID: PMC29347 Microbiology Maintenance of Epstein–Barr virus (EBV)
oriP-based episomes requires EBV-encoded nuclear
antigen-1 chromosome-binding domains, which can be replaced by
high-mobility group-I or histone H1 Siu Chun Hung, Myung-Soo Kang, and Elliott Kieff PMCID: PMC29348 Genetic transformation of HeLa cells by
Agrobacterium Talya Kunik, Tzvi Tzfira, Yoram Kapulnik, Yedidya Gafni, Colin Dingwall, and Vitaly Citovsky PMCID: PMC29349 Herpes simplex virus 1 α regulatory protein ICP0
functionally interacts with cellular transcription factor BMAL1 Yasushi Kawaguchi, Michiko Tanaka, Akihiko Yokoymama, Go Matsuda, Kentaro Kato, Hiroyuki Kagawa, Kanji Hirai, and Bernard Roizman PMCID: PMC29350 From the Cover:
The insect endosymbiont Sodalis glossinidius
utilizes a type III secretion system for cell invasion Colin Dale, Simon A. Young, Daniel T. Haydon, and Susan C. Welburn PMCID: PMC29351 A zinc finger-containing papain-like protease couples subgenomic
mRNA synthesis to genome translation in a positive-stranded
RNA virus Marieke A. Tijms, Leonie C. van Dinten, Alexander E. Gorbalenya, and Eric J. Snijder PMCID: PMC29352 Distinct and separate roles for herpesvirus-conserved UL97 kinase
in cytomegalovirus DNA synthesis and encapsidation Dana G. Wolf, Charmain Tan Courcelle, Mark N. Prichard, and Edward S. Mocarski PMCID: PMC29353 High-resolution minisatellite-based typing as a portable approach
to global analysis of Mycobacterium tuberculosis molecular epidemiology Edith Mazars, Sarah Lesjean, Anne-Laure Banuls, Michèle Gilbert, Véronique Vincent, Brigitte Gicquel, Michel Tibayrenc, Camille Locht, and Philip Supply PMCID: PMC29354 Neurobiology Dynamics of subjective contour formation in the early visual
cortex Tai Sing Lee and My Nguyen PMCID: PMC29355 Genetic and pharmacological disruption of neurokinin 1 receptor
function decreases anxiety-related behaviors and increases
serotonergic function Luca Santarelli, Gabriella Gobbi, Pierre C. Debs, Etienne L. Sibille, Pierre Blier, René Hen, and Mark J. S. Heath PMCID: PMC29356 Expression of membrane-associated carbonic anhydrase XIV on
neurons and axons in mouse and human brain Seppo Parkkila, Anna-Kaisa Parkkila, Hannu Rajaniemi, Gul N. Shah, Jeffrey H. Grubb, Abdul Waheed, and William S. Sly PMCID: PMC29357 Disfacilitation and active inhibition in the neocortex during the
natural sleep-wake cycle: An intracellular study Igor Timofeev, François Grenier, and Mircea Steriade PMCID: PMC29358 The effects of aging on gene expression in the hypothalamus and
cortex of mice Cecilia H. Jiang, Joe Z. Tsien, Peter G. Schultz, and Yinghe Hu PMCID: PMC29359 On a common circle: Natural scenes and Gestalt rules Mariano Sigman, Guillermo A. Cecchi, Charles D. Gilbert, and Marcelo O. Magnasco PMCID: PMC29360 Nontropic actions of neurotrophins: Subcortical nerve growth
factor gene delivery reverses age-related degeneration of primate
cortical cholinergic innervation J. M. Conner, M. A. Darracq, Jeff Roberts, and M. H. Tuszynski PMCID: PMC29361 Expression of γ-aminobutyric acid ρ1 and ρ1Δ450 as gene
fusions with the green fluorescent protein Ataúlfo Martínez-Torres and Ricardo Miledi PMCID: PMC29362 Estrogen receptor α, not β, is a critical link in
estradiol-mediated protection against brain injury Dena B. Dubal, Hong Zhu, Jin Yu, Shane W. Rau, Paul J. Shughrue, Istvan Merchenthaler, Mark S. Kindy, and Phyllis M. Wise PMCID: PMC29363 Female preproenkephalin-knockout mice display altered
emotional responses A. Ragnauth, A. Schuller, M. Morgan, J. Chan, S. Ogawa, J. Pintar, R. J. Bodnar, and D. W. Pfaff PMCID: PMC29364 An astroglia-linked dopamine D2-receptor action in prefrontal
cortex Zafar U. Khan, Peter Koulen, Marcelo Rubinstein, David K. Grandy, and Patricia S. Goldman-Rakic PMCID: PMC29365 The role of the D2 dopamine receptor
(D2R) in A2A adenosine receptor
(A2AR)-mediated behavioral and cellular responses as
revealed by A2A and D2 receptor
knockout mice Jiang-Fan Chen, Rosario Moratalla, Francesco Impagnatiello, David K. Grandy, Beatriz Cuellar, Marcelo Rubinstein, Mark A. Beilstein, Elizabeth Hackett, J. Stephen Fink, Malcolm J. Low, Ennio Ongini, and Michael A. Schwarzschild PMCID: PMC29366 Cocaine-predictive stimulus induces drug-seeking behavior and
neural activation in limbic brain regions after multiple months of
abstinence: Reversal by D1 antagonists Roberto Ciccocioppo, Pietro Paolo Sanna, and Friedbert Weiss PMCID: PMC29367 Hyperactivity and impaired response habituation in
hyperdopaminergic mice Xiaoxi Zhuang, Ronald S. Oosting, Sara R. Jones, Raul R. Gainetdinov, Gary W. Miller, Marc G. Caron, and René Hen PMCID: PMC29368 Pharmacology A second-generation vaccine protects against the psychoactive
effects of cocaine M. Rocío A. Carrera, Jon A. Ashley, Peter Wirsching, George F. Koob, and Kim D. Janda PMCID: PMC29369 Physiology Hypoxia-induced gene expression profiling in the euryoxic fish
Gillichthys mirabilis Andrew Y. Gracey, Joshua V. Troll, and George N. Somero PMCID: PMC29370 Hyperosmolality in the form of elevated NaCl but not urea causes
DNA damage in murine kidney cells Dietmar Kültz and Devulapalli Chakravarty PMCID: PMC29371 Proteolytic cleavage product of 30-kDa adipocyte
complement-related protein increases fatty acid oxidation in muscle
and causes weight loss in mice Joachim Fruebis, Tsu-Shuen Tsao, Sandrine Javorschi, Dana Ebbets-Reed, Mary Ruth S. Erickson, Frances T. Yen, Bernard E. Bihain, and Harvey F. Lodish PMCID: PMC29372 Targeted inactivation of sister of P-glycoprotein gene
(spgp) in mice results in nonprogressive but persistent
intrahepatic cholestasis Renxue Wang, Myriam Salem, Ibrahim M. Yousef, Beatriz Tuchweber, Ping Lam, Sarah J. Childs, Cheryl D. Helgason, Cameron Ackerley, M. James Phillips, and Victor Ling PMCID: PMC29373 Choline acetyltransferase mutations cause myasthenic syndrome
associated with episodic apnea in humans Kinji Ohno, Akira Tsujino, Joan M. Brengman, C. Michel Harper, Zeljko Bajzer, Bjarne Udd, Roger Beyring, Stephanie Robb, Fenella J. Kirkham, and Andrew G. Engel PMCID: PMC29374 Bimodal regulation of Na+–Ca2+ exchanger
by β-adrenergic signaling pathway in shark ventricular myocytes Sun-Hee Woo and Martin Morad PMCID: PMC29375 Neuroimaging of cerebral activations and deactivations associated
with hypercapnia and hunger for air Stephen Brannan, Mario Liotti, Gary Egan, Robert Shade, Lisa Madden, Rachel Robillard, Bart Abplanalp, Katie Stofer, Derek Denton, and Peter T. Fox PMCID: PMC29376 Brain responses associated with consciousness of breathlessness
(air hunger) Mario Liotti, Stephen Brannan, Gary Egan, Robert Shade, Lisa Madden, Bart Abplanalp, Rachel Robillard, Jack Lancaster, Frank E. Zamarripa, Peter T. Fox, and Derek Denton PMCID: PMC29377 Neuroimaging evidence implicating cerebellum in the experience of
hypercapnia and hunger for air Lawrence M. Parsons, Gary Egan, Mario Liotti, Stephen Brannan, Derek Denton, Robert Shade, Rachael Robillard, Lisa Madden, Bart Abplanalp, and Peter T. Fox PMCID: PMC29378 Plant Biology Plastid redox state and sugars: Interactive regulators of
nuclear-encoded photosynthetic gene expression Oliver Oswald, Thomas Martin, Peter J. Dominy, and Ian A. Graham PMCID: PMC29379 Arabidopsis genomes uncoupled 5
(GUN5) mutant reveals the involvement of Mg-chelatase H
subunit in plastid-to-nucleus signal transduction Nobuyoshi Mochizuki, Judy A. Brusslan, Robert Larkin, Akira Nagatani, and Joanne Chory PMCID: PMC29380 Ancient origin of pathogen recognition specificity conferred by
the tomato disease resistance gene Pto Brendan K. Riely and Gregory
B. Martin PMCID: PMC29381 The CYP88A cytochrome P450, ent-kaurenoic acid
oxidase, catalyzes three steps of the gibberellin biosynthesis pathway Chris A. Helliwell, Peter M. Chandler, Andrew Poole, Elizabeth S. Dennis, and W. James Peacock PMCID: PMC29382 Population Biology Does clutch size evolve in response to parasites
and immunocompetence? Thomas E. Martin, A. P. Møller, S. Merino, and J. Clobert PMCID: PMC29383 Psychology Local and global attention are mapped retinotopically in human
occipital cortex Yuka Sasaki, Nouchine Hadjikhani, Bruce Fischl, Arthur K. Liu, Sean Marret, Anders M. Dale, and Roger B. H. Tootell PMCID: PMC29384 Sleep modifies retinal ganglion cell responses in the normal rat Robert Galambos, Orsolya Szabó-Salfay, Erzsébet Szatmári, Nóra Szilágyi, and Gábor Juhász PMCID: PMC29385 Galantamine: Effect on nicotinic receptor binding,
acetylcholinesterase inhibition, and learning Diana S. Woodruff-Pak, Richard W. Vogel, III, and Gary L. Wenk PMCID: PMC29386 The neural basis of task-switching in working memory: Effects of
performance and aging Edward E. Smith, Anat Geva, John Jonides, Andrea Miller, Patricia Reuter-Lorenz, and Robert A. Koeppe PMCID: PMC29387 Social Sciences Anthropology From the Cover:
Evidence of termite foraging by Swartkrans early hominids Lucinda R. Backwell and Francesco d'Errico PMCID: PMC29261 The earliest archaeological maize (Zea mays L.)
from highland Mexico: New accelerator mass spectrometry dates and
their implications D. R. Piperno and K. V. Flannery PMCID: PMC29388 Archaeological evidence of teosinte domestication from
Guilá Naquitz, Oaxaca Bruce F. Benz PMCID: PMC29389 Ancient Maya documents concerning the movements of Mars Harvey M. Bricker, Anthony F. Aveni, and Victoria R. Bricker PMCID: PMC29390 Corrections Proc Natl Acad Sci U S A. 2001 February 13; 98(4): 2111. PMCID: PMC55935 Corrects: Laurent Coscoy, et al. Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis. Proc Natl Acad Sci U S A. 2000 July 5; 97(14): 8051–8056. Proc Natl Acad Sci U S A. 2001 February 13; 98(4): 2111. Published online 2001 February 6. PMCID: PMC55936 Corrects: Sergei N. Rodin, et al. Human lung cancer and p53: The interplay between
mutagenesis and selection. Proc Natl Acad Sci U S A. 2000 October 24; 97(22): 12244–12249. |
