| | This journal provides immediate access to some articles. From the Academy Frontiers of Science Symposium Introduction to Frontiers of Science PMCID: PMC34074 Polyglutamine disease and neuronal cell death Henry L. Paulson, Nancy M. Bonini, and Kevin A. Roth PMCID: PMC34075 Does the granular matter? Heinrich M. Jaeger, Troy Shinbrot, and Paul B. Umbanhowar PMCID: PMC34076 Life in extreme environments: Hydrothermal vents Robert A. Zierenberg, Michael W. W. Adams, and Alissa J. Arp PMCID: PMC34077 Advances in random matrix theory, zeta functions, and sphere
packing T. C. Hales, P. Sarnak, and M. C. Pugh PMCID: PMC34078 Commentaries Calcium signaling and acute pancreatitis: Specific response to a
promiscuous messenger Anant B. Parekh PMCID: PMC34065 A guided tour in protein interaction space: Coiled coils from the
yeast proteome James C. Hu PMCID: PMC34066 From the Cover:
Activation of Rubisco regulates photosynthesis at high
temperature and CO2 Richard G. Jensen PMCID: PMC34067 Progress in understanding angiosperm history, success, and
relationships: Darwin's abominably “perplexing phenomenon” William L. Crepet PMCID: PMC34068 Family matters: Kin selection and the evolution of conspecific
brood parasitism Bruce E. Lyon and John McA. Eadie PMCID: PMC34069 Ubiquitin in retrovirus assembly: Actor or bystander? Volker M. Vogt PMCID: PMC34070 Avian chemical defense: Toxic birds not of a feather Paul J. Weldon PMCID: PMC34071 A novel helper role for CD4 T cells Joke M. M. den Haan and Michael J. Bevan PMCID: PMC34072 Dangerous liaisons William R. Rice PMCID: PMC34073 Physical Sciences Chemistry Small molecule developmental screens reveal the logic and timing
of vertebrate development Randall T. Peterson, Brian A. Link, John E. Dowling, and Stuart L. Schreiber PMCID: PMC27161 From the Cover:
Batrachotoxin alkaloids from passerine birds: A second toxic
bird genus (Ifrita kowaldi) from
New Guinea J. P. Dumbacher, T. F. Spande, and J. W. Daly PMCID: PMC27162 Dynamics and folding of single two-stranded coiled-coil peptides
studied by fluorescent energy transfer confocal microscopy David S. Talaga, Wai Leung Lau, Heinrich Roder, Jianyong Tang, Yiwei Jia, William F. DeGrado, and Robin M. Hochstrasser PMCID: PMC27171 Statistics Efficiency of the u,v method of estimation Herbert Robbins and Cun-Hui Zhang PMCID: PMC27163 Biological Sciences Agricultural Sciences Frequency of resistance to Bacillus thuringiensis
in field populations of pink bollworm Bruce E. Tabashnik, Amanda L. Patin, Timothy J. Dennehy, Yong-Biao Liu, Yves Carrière, Maria A. Sims, and Larry Antilla PMCID: PMC27164 Biochemistry A mutant allele of essential, general translation initiation
factor DED1 selectively inhibits translation of a
viral mRNA Amine O. Noueiry, Jianbo Chen, and Paul Ahlquist PMCID: PMC27165 Effect of the protein import machinery at the mitochondrial
surface on precursor stability Shihai Huang, Sherry Murphy, and Andreas Matouschek PMCID: PMC27166 A dual-specificity aminoacyl-tRNA synthetase in the deep-rooted
eukaryote Giardia lamblia Shipra Bunjun, Constantinos Stathopoulos, David Graham, Bokkee Min, Makoto Kitabatake, Alice L. Wang, Ching C. Wang, Christian P. Vivarès, Louis M. Weiss, and Dieter Söll PMCID: PMC27167 The design, synthesis, and evaluation of molecules that enable or
enhance cellular uptake: Peptoid molecular transporters Paul A. Wender, Dennis J. Mitchell, Kanaka Pattabiraman, Erin T. Pelkey, Lawrence Steinman, and Jonathan B. Rothbard PMCID: PMC27168 Differential gene expression in p53-mediated
apoptosis-resistant vs. apoptosis-sensitive tumor
cell lines Steve A. Maxwell and George E. Davis PMCID: PMC27169 The human SWI/SNF-B chromatin-remodeling complex is related to
yeast Rsc and localizes at kinetochores of mitotic chromosomes Yutong Xue, Julie C. Canman, Cheol Soon Lee, Zuqin Nie, Dafeng Yang, G. Tony Moreno, Mary K. Young, E. D. Salmon, and Weidong Wang PMCID: PMC27170 Dynamics and folding of single two-stranded coiled-coil peptides
studied by fluorescent energy transfer confocal microscopy David S. Talaga, Wai Leung Lau, Heinrich Roder, Jianyong Tang, Yiwei Jia, William F. DeGrado, and Robin M. Hochstrasser PMCID: PMC27171 A nucleolar protein related to ribosomal protein L7 is required
for an early step in large ribosomal subunit biogenesis David A. Dunbar, François Dragon, Sarah J. Lee, and Susan J. Baserga PMCID: PMC27172 Identification of the vitamin K-dependent carboxylase active
site: Cys-99 and Cys-450 are required for both epoxidation
and carboxylation B. Nirmala Pudota, Masaru Miyagi, Kevin W. Hallgren, Karen A. West, John W. Crabb, Kunio S. Misono, and Kathleen L. Berkner PMCID: PMC27173 Interaction of two arginine residues in lactate oxidase with the
enzyme flavin: Conversion of FMN to 8-formyl-FMN Kazuko Yorita, Takeshi Matsuoka, Hideo Misaki, and Vincent Massey PMCID: PMC27174 Multiple quantum solid-state NMR indicates a parallel, not
antiparallel, organization of β-sheets in Alzheimer's
β-amyloid fibrils Oleg N. Antzutkin, John J. Balbach, Richard D. Leapman, Nancy W. Rizzo, Jennifer Reed, and Robert Tycko PMCID: PMC27175 Essential role of Glu-C66 for menaquinol oxidation indicates
transmembrane electrochemical potential generation by Wolinella
succinogenes fumarate reductase C. Roy D. Lancaster, Roland Groß, Alexander Haas, Michaela Ritter, Werner Mäntele, Jörg Simon, and Achim Kröger PMCID: PMC27176 Proteasome inhibition interferes with Gag polyprotein
processing, release, and maturation of HIV-1 and HIV-2 Ulrich Schubert, David E. Ott, Elena N. Chertova, Reinhold Welker, Uwe Tessmer, Michael F. Princiotta, Jack R. Bennink, Hans-Georg Kräusslich, and Jonathan W. Yewdell PMCID: PMC27177 A role for ubiquitin ligase recruitment in retrovirus release Bettina Strack, Arianna Calistri, Molly A. Accola, Giorgio Palù, and Heinrich G. Göttlinger PMCID: PMC27178 Ubiquitin is part of the retrovirus budding machinery Akash Patnaik, Vincent Chau, and John W. Wills PMCID: PMC27179 Biophysics Physical reasons for the unusual α-helix stabilization afforded
by charged or neutral polar residues in alanine-rich peptides Jorge A. Vila, Daniel R. Ripoll, and H. A. Scheraga PMCID: PMC27180 Crystal structure of yeast initiation factor 4A, a DEAD-box
RNA helicase Jonathan M. Caruthers, Eric R. Johnson, and David B. McKay PMCID: PMC27181 Identification of the proton pathway in bacterial reaction
centers: Both protons associated with reduction of QB
to QBH2 share a common entry point Pia Ädelroth, Mark L. Paddock, Laura B. Sagle, George Feher, and Melvin Y. Okamura PMCID: PMC27182 Measuring the forces involved in polyvalent adhesion of
uropathogenic Escherichia coli to mannose-presenting
surfaces Michael N. Liang, Stephen P. Smith, Steven J. Metallo, Insung S. Choi, Mara Prentiss, and George M. Whitesides PMCID: PMC27183 A host–guest system to study structure–function
relationships of membrane fusion peptides Xing Han and Lukas K. Tamm PMCID: PMC27184 Cell Biology Regulation of apoptosis at cell division by
p34cdc2 phosphorylation of survivin Daniel S. O'Connor, Douglas Grossman, Janet Plescia, Fengzhi Li, Hui Zhang, Antonello Villa, Simona Tognin, Pier Carlo Marchisio, and Dario C. Altieri PMCID: PMC27185 A CBF5 mutation that disrupts nucleolar
localization of early tRNA biosynthesis in yeast also suppresses tRNA
gene-mediated transcriptional silencing Ann Kendall, Melissa W. Hull, Edouard Bertrand, Paul D. Good, Robert H. Singer, and David R. Engelke PMCID: PMC27186 Apical sorting of a voltage- and Ca2+-activated
K+ channel α-subunit in Madin-Darby canine kidney cells is independent of N-glycosylation Marcela Bravo-Zehnder, Patricio Orio, Andrés Norambuena, Martin Wallner, Pratap Meera, Ligia Toro, Ramón Latorre, and Alfonso González PMCID: PMC27187 Meiotic lamin C2: The unique amino-terminal hexapeptide GNAEGR is
essential for nuclear envelope association Manfred Alsheimer, Elisabeth von Glasenapp, Martina Schnölzer, Hans Heid, and Ricardo Benavente PMCID: PMC27188 Calcium-dependent enzyme activation and vacuole formation in the
apical granular region of pancreatic acinar cells Michael Raraty, Jeremy Ward, Gul Erdemli, Camille Vaillant, John P. Neoptolemos, Robert Sutton, and Ole H. Petersen PMCID: PMC27189 Developmental Biology Small molecule developmental screens reveal the logic and timing
of vertebrate development Randall T. Peterson, Brian A. Link, John E. Dowling, and Stuart L. Schreiber PMCID: PMC27161 Coordinate control of translation and localization of Vg1 mRNA in
Xenopus oocytes James E. Wilhelm, Ronald D. Vale, and Ramanujan S. Hegde PMCID: PMC27190 Targeted chromatin binding and histone acetylation in
vivo by thyroid hormone receptor during amphibian development Laurent M. Sachs and Yun-Bo Shi PMCID: PMC27191 Pax8 has a key role in thyroid cell differentiation Marina Pasca di Magliano, Roberto Di Lauro, and Mariastella Zannini PMCID: PMC27192 Ecology From the Cover:
Batrachotoxin alkaloids from passerine birds: A second toxic
bird genus (Ifrita kowaldi) from
New Guinea J. P. Dumbacher, T. F. Spande, and J. W. Daly PMCID: PMC27162 Invariant size–frequency distributions along a latitudinal
gradient in marine bivalves Kaustuv Roy, David Jablonski, and Karen K. Martien PMCID: PMC27193 Evolution Dynamic expression of multiple scavenger receptor cysteine-rich
genes in coelomocytes of the purple sea urchin Zeev Pancer PMCID: PMC27194 Correlated effects of sperm competition and postmating
female mortality Alberto Civetta and Andrew G. Clark PMCID: PMC27195 From the Cover:
Independent and combined analyses of sequences from all three
genomic compartments converge on the root of flowering
plant phylogeny Todd J. Barkman, Gordon Chenery, Joel R. McNeal, James Lyons-Weiler, Wayne J. Ellisens, Gerry Moore, Andrea D. Wolfe, and Claude W. dePamphilis PMCID: PMC27196 Isoprenoid biosynthesis: The evolution of two ancient and
distinct pathways across genomes B. Markus Lange, Tamas Rujan, William Martin, and Rodney Croteau PMCID: PMC27197 Molecular phylogenetic analysis of evolutionary trends in
stonefly wing structure and locomotor behavior Michael A. Thomas, Kathleen A. Walsh, Melisande R. Wolf, Bruce A. McPheron, and James H. Marden PMCID: PMC27198 Manipulation of the phenolic chemistry of willows by
gall-inducing sawflies Tommi Nyman and Riitta Julkunen-Tiitto PMCID: PMC27199 Host–parasite relatedness shown by protein fingerprinting in a
brood parasitic bird Malte Andersson and Matti Åhlund PMCID: PMC27200 Morphological castes in a vertebrate M. J. O'Riain, J. U. M. Jarvis, R. Alexander, R. Buffenstein, and C. Peeters PMCID: PMC27201 Genetics The human sex-reversing ATRX gene has a homologue on the
marsupial Y chromosome, ATRY: Implications for the evolution of mammalian sex determination Andrew Pask, Marilyn B. Renfree, and Jennifer A. Marshall Graves PMCID: PMC27202 From the Cover:
A computationally directed screen identifying interacting coiled
coils from Saccharomyces cerevisiae John R. S. Newman, Ethan Wolf, and Peter S. Kim PMCID: PMC27203 Mice with a targeted mutation in the thyroid hormone β receptor
gene exhibit impaired growth and resistance to thyroid hormone Masahiro Kaneshige, Kumiko Kaneshige, Xu-guang Zhu, Alexandra Dace, Lisa Garrett, Todd A. Carter, Rasa Kazlauskaite, Daniel G. Pankratz, Anthony Wynshaw-Boris, Samuel Refetoff, Bruce Weintraub, Mark C. Willingham, Carrolee Barlow, and Sheue-yann Cheng PMCID: PMC27204 Mechanism for a transcriptional activator that works at the
isomerization step Simon L. Dove, Franklin W. Huang, and Ann Hochschild PMCID: PMC27205 Delivery of a stringent dimerizer-regulated gene expression
system in a single retroviral vector Roy Pollock, Robbyn Issner, Karen Zoller, Sridaran Natesan, Victor M. Rivera, and Tim Clackson PMCID: PMC27206 A chemical genomics approach toward understanding the global
functions of the target of rapamycin protein (TOR) Ting-Fung Chan, John Carvalho, Linda Riles, and X. F. Steven Zheng PMCID: PMC27207 ROP-1, an RNA quality-control pathway component, affects
Caenorhabditis elegans dauer formation Jean-Claude Labbé, Jason Burgess, Luis A. Rokeach, and Siegfried Hekimi PMCID: PMC27208 Y chromosomal fertility factors kl-2 and
kl-3 of Drosophila melanogaster encode
dynein heavy chain polypeptides Antonio Bernardo Carvalho, Brian P. Lazzaro, and Andrew G. Clark PMCID: PMC27209 Minisatellite marker analysis of Trypanosoma
brucei: Reconciliation of clonal, panmictic, and epidemic
population genetic structures Annette MacLeod, Alison Tweedie, Susan C. Welburn, Ian Maudlin, C. Michael R. Turner, and Andy Tait PMCID: PMC27243 Immunology Paired Ig-like receptor homologs in birds and mammals share a
common ancestor with mammalian Fc receptors Glynn Dennis, Jr., Hiromi Kubagawa, and Max D. Cooper PMCID: PMC27210 Posttranslational modification of the glycosylation inhibiting
factor (GIF) gene product generates bioactive GIF Hiroshi Watarai, Risa Nozawa, Ayako Tokunaga, Noriko Yuyama, Mayumi Tomas, Atsushi Hinohara, Kimishige Ishizaka, and Yasuyuki Ishii PMCID: PMC27211 Suppressor T cells regulate the nonanergic cell population that
remains after peripheral tolerance is induced to the Mls-1 antigen in T cell receptor Vβ8.1 transgenic mice Hironori Maeda, Shigeyoshi Fujimoto, and Mark I. Greene PMCID: PMC27212 Protective long-term antibody memory by antigen-driven and T
help-dependent differentiation of long-lived memory B cells to
short-lived plasma cells independent of secondary lymphoid organs Adrian F. Ochsenbein, Daniel D. Pinschewer, Sophie Sierro, Edit Horvath, Hans Hengartner, and Rolf M. Zinkernagel PMCID: PMC27213 From the Cover:
Functional cooperation between T helper cell determinants Mara Gerloni, Sidong Xiong, Sonjoy Mukerjee, Stephen P. Schoenberger, Michael Croft, and Maurizio Zanetti PMCID: PMC27214 Medical Sciences Prostacyclin-mediated activation of peroxisome
proliferator-activated receptor δ in colorectal cancer Rajnish A. Gupta, Jian Tan, Wade F. Krause, Mark W. Geraci, Timothy M. Willson, Sudhansu K. Dey, and Raymond N. DuBois PMCID: PMC27215 Posttranslational modification of TEL and TEL/AML1 by SUMO-1
and cell-cycle-dependent assembly into nuclear bodies Subhra Ranjan Chakrabarti, Rashmi Sood, Suvobroto Nandi, and Giuseppina Nucifora PMCID: PMC27216 INAUGURAL ARTICLE by a Recently Elected Academy Member: National burden of disease in India from indoor air pollution Kirk R. Smith PMCID: PMC27217 Long-term expression of γ-globin mRNA in mouse erythrocytes
from retrovirus vectors containing the human γ-globin gene fused
to the ankyrin-1 promoter Denise E. Sabatino, Nancy E. Seidel, Guillermo J. Aviles-Mendoza, Amanda P. Cline, Stacie M. Anderson, Patrick G. Gallagher, and David M. Bodine PMCID: PMC27218 Induction of tolerance to immunogenic tumor antigens associated
with lymphomagenesis in HOX11 transgenic mice Suzana Rosic-Kablar, Kin Chan, Marciano D. Reis, Ian D. Dubé, and Margaret R. Hough PMCID: PMC27219 Acquired, nonrandom chromosomal abnormalities associated with the
development of acute promyelocytic leukemia in transgenic mice Drazen B. Zimonjic, Jessica L. Pollock, Peter Westervelt, Nicholas C. Popescu, and Timothy J. Ley PMCID: PMC27220 Survival motor neuron protein modulates
neuron-specific apoptosis Douglas A. Kerr, Jocelyn P. Nery, Richard J. Traystman, B. Nelson Chau, and J. Marie Hardwick PMCID: PMC27221 Hepatitis C virus lacking the hypervariable region 1 of the
second envelope protein is infectious and causes acute resolving or
persistent infection in chimpanzees Xavier Forns, Robert Thimme, Sugantha Govindarajan, Suzanne U. Emerson, Robert H. Purcell, Francis V. Chisari, and Jens Bukh PMCID: PMC27222 Microbiology Molecular signals required for type III secretion and
translocation of the Xanthomonas campestris AvrBs2
protein to pepper plants Mary Beth Mudgett, Olga Chesnokova, Doug Dahlbeck, Eszter T. Clark, Ombeline Rossier, Ulla Bonas, and Brian J. Staskawicz PMCID: PMC27223 Rational design of a global inhibitor of the virulence response
in Staphylococcus aureus, based in part on localization
of the site of inhibition to the receptor-histidine kinase, AgrC Gholson J. Lyon, Patricia Mayville, Tom W. Muir, and Richard P. Novick PMCID: PMC27224 Neurobiology High-resolution structure of hair-cell tip links Bechara Kachar, Marianne Parakkal, Mauricio Kurc, Yi-dong Zhao, and Peter G. Gillespie PMCID: PMC27225 Capture of a protein synthesis-dependent component of
long-term depression Beth S. Kauderer and Eric R. Kandel PMCID: PMC27226 A preference for own-subspecies' song guides vocal learning in a
song bird Douglas A. Nelson PMCID: PMC27227 Parkin functions as an E2-dependent ubiquitin– protein ligase
and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1 Yi Zhang, Jun Gao, Kenny K. K. Chung, Hui Huang, Valina L. Dawson, and Ted M. Dawson PMCID: PMC27228 Remodeling of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic
acid receptor subunit composition in hippocampal neurons after
global ischemia Thoralf Optiz, Sonja Y. Grooms, Michael V. L. Bennett, and R. Suzanne Zukin PMCID: PMC27229 Region-specific differentiation of neural tube-derived neuronal
restricted progenitor cells after heterotopic transplantation Hui Yang, Tahimina Mujtaba, Giri Venkatraman, Yuan Yuan Wu, Mahendra S. Rao, and Marla B. Luskin PMCID: PMC27230 Role of the calcium-binding protein parvalbumin in short-term
synaptic plasticity Olivier Caillard, Herman Moreno, Beat Schwaller, Isabel Llano, Marco R. Celio, and Alain Marty PMCID: PMC27231 Gene-experience interaction alters the cholinergic
septohippocampal pathway of mice Andrew I. Brooks, Deborah A. Cory-Slechta, and Howard J. Federoff PMCID: PMC27232 Requirement for the lpA1
lysophosphatidic acid receptor gene in normal suckling behavior James J. A. Contos, Nobuyuki Fukushima, Joshua A. Weiner, Dhruv Kaushal, and Jerold Chun PMCID: PMC27233 Physiology The neuroprotective effect of pituitary adenylate
cyclase-activating polypeptide on cerebellar granule cells is
mediated through inhibition of the CED3-related cysteine
protease caspase-3/CPP32 David Vaudry, Bruno J. Gonzalez, Magali Basille, Tommy F. Pamantung, Marc Fontaine, Alain Fournier, and Hubert Vaudry PMCID: PMC27234 Plant Biology A cyclin-dependent kinase-activating kinase regulates
differentiation of root initial cells in Arabidopsis Masaaki Umeda, Chikage Umeda-Hara, and Hirofumi Uchimiya PMCID: PMC27235 Virus-encoded suppressor of posttranscriptional gene silencing
targets a maintenance step in the silencing pathway Cesar Llave, Kristin D. Kasschau, and James C. Carrington PMCID: PMC27236 Genetic analysis of calcium spiking responses in nodulation
mutants of Medicago truncatula Rebecca J. Wais, Christine Galera, Giles Oldroyd, Romy Catoira, R. Varma Penmetsa, Douglas Cook, Clare Gough, Jean Dénarié, and Sharon R. Long PMCID: PMC27237 Dissection of nodulation signaling using pea mutants defective
for calcium spiking induced by Nod factors and chitin oligomers Simon A. Walker, Virginie Viprey, and J. Allan Downie PMCID: PMC27238 Phytochrome B binds with greater apparent affinity than
phytochrome A to the basic helix–loop–helix factor PIF3 in a
reaction requiring the PAS domain of PIF3 Yuxian Zhu, James M. Tepperman, Craig D. Fairchild, and Peter H. Quail PMCID: PMC27239 UV-damage-mediated induction of homologous recombination in
Arabidopsis is dependent on photosynthetically
active radiation Gerhard Ries, Günther Buchholz, Hanns Frohnmeyer, and Barbara Hohn PMCID: PMC27240 Rubisco activase constrains the photosynthetic potential of
leaves at high temperature and CO2 Steven J. Crafts-Brandner and Michael E. Salvucci PMCID: PMC27241 Subgenome chromosome walking in wheat: A 450-kb physical contig
in Triticum monococcum L. spans the
Lr10 resistance locus in hexaploid
wheat (Triticum aestivum L.) Nils Stein, Catherine Feuillet, Thomas Wicker, Edith Schlagenhauf, and Beat Keller PMCID: PMC27242 Population Biology Minisatellite marker analysis of Trypanosoma
brucei: Reconciliation of clonal, panmictic, and epidemic
population genetic structures Annette MacLeod, Alison Tweedie, Susan C. Welburn, Ian Maudlin, C. Michael R. Turner, and Andy Tait PMCID: PMC27243 Psychology INAUGURAL ARTICLE by a Recently Elected Academy Member: The role of prefrontal cortex and posterior parietal cortex in
task switching Myeong-Ho Sohn, Stefan Ursu, John R. Anderson, V. Andrew Stenger, and Cameron S. Carter PMCID: PMC27244 Temporal distribution of the ganglion cell volleys in the normal
rat optic nerve Robert Galambos, Orsolya Szabó-Salfay, Péter Barabás, János Pálhalmi, Nóra Szilágyi, and Gábor Juhász PMCID: PMC27245 Correction Proc Natl Acad Sci U S A. 2000 November 21; 97(24): 13460. Published online 2000 November 7. PMCID: PMC56177 Corrects: Brian Kuhlman, et al. Native protein sequences are close to optimal for their structures. Proc Natl Acad Sci U S A. 2000 September 12; 97(19): 10383–10388. |
