| | This journal provides immediate access to some articles. Editorial Power to the People: PubMed Central Nicholas R. Cozzarelli PMCID: PMC33956 Commentaries Predicting the range of linkage disequilibrium Jurg Ott PMCID: PMC33508 Connections between the processing and nuclear export of mRNA:
Evidence for an export license? Bryan R. Cullen PMCID: PMC33509 Physical Sciences Chemistry Manipulating the genetic identity and biochemical surface properties of individual cells with electric-field-induced fusion Anette Strömberg, Frida Ryttsén, Daniel T. Chiu, Max Davidson, Peter S. Eriksson, Clyde F. Wilson, Owe Orwar, and Richard N. Zare PMCID: PMC26606 Specific molecular recognition of mixed nucleic acid sequences: An aromatic dication that binds in the DNA minor groove as a dimer Lei Wang, Christian Bailly, Arvind Kumar, Daoyuan Ding, Miroslav Bajic, David W. Boykin, and W. David Wilson PMCID: PMC26607 Denaturant-induced movement of the transition state of protein
folding revealed by high-pressure stopped-flow measurements Günter Pappenberger, Christophe Saudan, Michael Becker, André E. Merbach, and Thomas Kiefhaber PMCID: PMC26608 Effects of unique ion chemistry on thin-film growth by plasma–surface interactions Muthu B. J. Wijesundara, Luke Hanley, Boris Ni, and Susan B. Sinnott PMCID: PMC26609 Differential quantal release of histamine and 5-hydroxytryptamine
from mast cells of vesicular monoamine transporter 2 knockout mice Eric R. Travis, Yan-Min Wang, Darren J. Michael, Marc G. Caron, and R. Mark Wightman PMCID: PMC26633 Physics From the Cover:
The Theory of Everything R. B. Laughlin and David Pines PMCID: PMC26610 The middle way R. B. Laughlin, David Pines, Joerg Schmalian, Branko P. Stojković, and Peter Wolynes PMCID: PMC26611 Biological Sciences Applied Biological Sciences Exercise-induced changes in expression and activity of proteins involved in insulin signal transduction in skeletal muscle: Differential effects on insulin-receptor substrates 1 and 2 Alexander V. Chibalin, Mei Yu, Jeffrey W. Ryder, Xiao Mei Song, Dana Galuska, Anna Krook, Harriet Wallberg-Henriksson, and Juleen R. Zierath PMCID: PMC26612 Biochemistry Specific molecular recognition of mixed nucleic acid sequences: An aromatic dication that binds in the DNA minor groove as a dimer Lei Wang, Christian Bailly, Arvind Kumar, Daoyuan Ding, Miroslav Bajic, David W. Boykin, and W. David Wilson PMCID: PMC26607 Transglutaminase-catalyzed crosslinking of the Aα and γ constituent chains in fibrinogen S. N. Prasanna Murthy, James H. Wilson, Thomas J. Lukas, Yuri Veklich, John W. Weisel, and Laszlo Lorand PMCID: PMC26613 Structural interactions of fibroblast growth factor receptor with its ligands Deborah J. Stauber, Anna D. DiGabriele, and Wayne A. Hendrickson PMCID: PMC26614 Signal recognition particle components in the nucleolus Joan C. Politz, Serge Yarovoi, Susan M. Kilroy, Krishne Gowda, Christian Zwieb, and Thoru Pederson PMCID: PMC26615 Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression Ann L. Benko, Gabriela Vaduva, Nancy C. Martin, and Anita K. Hopper PMCID: PMC26616 Inactive conformation of the serpin α1-antichymotrypsin indicates two-stage insertion of the reactive loop: Implications for inhibitory function and conformational disease Bibek Gooptu, Bart Hazes, Wun-Shaing W. Chang, Timothy R. Dafforn, Robin W. Carrell, Randy J. Read, and David A. Lomas PMCID: PMC26617 From the Cover:
Three-dimensional structure of poliovirus receptor bound to poliovirus David M. Belnap, Brian M. McDermott, Jr., David J. Filman, Naiqian Cheng, Benes L. Trus, Harmon J. Zuccola, Vincent R. Racaniello, James M. Hogle, and Alasdair C. Steven PMCID: PMC26618 From the Cover:
Interaction of the poliovirus receptor with poliovirus Yongning He, Valorie D. Bowman, Steffen Mueller, Carol M. Bator, Jordi Bella, Xiaozhong Peng, Timothy S. Baker, Eckard Wimmer, Richard J. Kuhn, and Michael G. Rossmann PMCID: PMC26619 The crystal structure of modified bovine fibrinogen Jerry H. Brown, Niels Volkmann, Gyo Jun, Agnes H. Henschen-Edman, and Carolyn Cohen PMCID: PMC26620 IFN consensus sequence binding protein potentiates STAT1-dependent activation of IFNγ-responsive promoters in macrophages Cristina Contursi, I-Ming Wang, Lucia Gabriele, Massimo Gadina, John O'Shea, Herbert C. Morse, III, and Keiko Ozato PMCID: PMC26621 Substitutions in the aspartate transcarbamoylase domain of hamster CAD disrupt oligomeric structure Yu Qiu and Jeffrey N. Davidson PMCID: PMC26622 Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation Betsy M. Sutherland, Paula V. Bennett, Olga Sidorkina, and Jacques Laval PMCID: PMC26623 PTGF-β, a type β transforming growth factor (TGF-β) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-β signaling pathway Mingjia Tan, Yixin Wang, Kunliang Guan, and Yi Sun PMCID: PMC26624 Role of adenine functional groups in the recognition of the 3′-splice-site AG during the second step of pre-mRNA splicing Rajesh K. Gaur, Leonid Beigelman, Peter Haeberli, and Tom Maniatis PMCID: PMC26625 Yeast flavin-containing monooxygenase is induced by the unfolded protein response Jung-Keun Suh and Jon D. Robertus PMCID: PMC26626 Biophysics Denaturant-induced movement of the transition state of protein
folding revealed by high-pressure stopped-flow measurements Günter Pappenberger, Christophe Saudan, Michael Becker, André E. Merbach, and Thomas Kiefhaber PMCID: PMC26608 The middle way R. B. Laughlin, David Pines, Joerg Schmalian, Branko P. Stojković, and Peter Wolynes PMCID: PMC26611 Pulling a single chromatin fiber reveals the forces that maintain its higher-order structure Yujia Cui and Carlos Bustamante PMCID: PMC26627 Staphylococcal protein A: Unfolding pathways, unfolded states, and differences between the B and E domains Darwin O. V. Alonso and Valerie Daggett PMCID: PMC26628 Solid-state synthesis and mechanical unfolding of polymers of T4 lysozyme Guoliang Yang, Ciro Cecconi, Walter A. Baase, Ingrid R. Vetter, Wendy A. Breyer, Julie A. Haack, Brian W. Matthews, Frederick W. Dahlquist, and Carlos Bustamante PMCID: PMC26629 NMR solution structure of the human prion protein Ralph Zahn, Aizhuo Liu, Thorsten Lührs, Roland Riek, Christine von Schroetter, Francisco López García, Martin Billeter, Luigi Calzolai, Gerhard Wider, and Kurt Wüthrich PMCID: PMC26630 Fluorescence correlation spectroscopy reveals fast optical excitation-driven intramolecular dynamics of yellow fluorescent proteins Petra Schwille, Susanne Kummer, Ahmed A. Heikal, W. E. Moerner, and Watt W. Webb PMCID: PMC26631 Kinetic equilibrium of forces and molecular events in muscle contraction Erwin W. Becker PMCID: PMC26632 Cell Biology Differential quantal release of histamine and 5-hydroxytryptamine
from mast cells of vesicular monoamine transporter 2 knockout mice Eric R. Travis, Yan-Min Wang, Darren J. Michael, Marc G. Caron, and R. Mark Wightman PMCID: PMC26633 Involvement of protein kinase A in fibroblast growth
factor-2-activated transcription Juha-Pekka Pursiheimo, Markku Jalkanen, Kjetil Taskén, and Panu Jaakkola PMCID: PMC26634 Coculturing diverse clonal populations prevents the early-stage neoplastic progression that occurs in the separate clones Ming Chow and Harry Rubin PMCID: PMC26635 Analysis of receptor signaling pathways by mass spectrometry: Identification of Vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors Akhilesh Pandey, Alexandre V. Podtelejnikov, Blagoy Blagoev, Xosé R. Bustelo, Matthias Mann, and Harvey F. Lodish PMCID: PMC26636 Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway Jean-Paul Mira, Valerie Benard, John Groffen, Luraynne C. Sanders, and Ulla G. Knaus PMCID: PMC26637 Developmental Biology Overexpression of Xenopus laevis growth hormone stimulates growth of tadpoles and frogs Haochu Huang and Donald D. Brown PMCID: PMC26638 Prolactin is not a juvenile hormone in Xenopus laevis metamorphosis Haochu Huang and Donald D. Brown PMCID: PMC26639 Evolution Chloroplast protein and centrosomal genes, a tRNA intron, and odd telomeres in an unusually compact eukaryotic genome, the cryptomonad nucleomorph Stefan Zauner, Martin Fraunholz, Jürgen Wastl, Susanne Penny, Margaret Beaton, Thomas Cavalier-Smith, Uwe-G. Maier, and Susan Douglas PMCID: PMC26640 Molecular cytogenetic dissection of human chromosomes 3 and 21 evolution S. Müller, R. Stanyon, P. Finelli, N. Archidiacono, and J. Wienberg PMCID: PMC26641 Molecular heterochrony in the early development of Drosophila Junhyong Kim, Jonita Q. Kerr, and Gi-Sik Min PMCID: PMC26642 Genetics Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice Poornima Upadhya, Edward H. Birkenmeier, Connie S. Birkenmeier, and Jane E. Barker PMCID: PMC26643 Quantifying single gene copy number by measuring fluorescent probe lengths on combed genomic DNA John Herrick, Xavier Michalet, Chiara Conti, Catherine Schurra, and Aaron Bensimon PMCID: PMC26644 Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma Yaping Shou, Maria L. Martelli, Ana Gabrea, Ying Qi, Leslie A. Brents, Anna Roschke, Gordon Dewald, Ilan R. Kirsch, P. Leif Bergsagel, and W. Michael Kuehl PMCID: PMC26645 Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock Yi Liu, Jennifer Loros, and Jay C. Dunlap PMCID: PMC26646 Guanidine hydrochloride blocks a critical step in the propagation of the prion-like determinant [PSI+] of Saccharomyces cerevisiae Simon S. Eaglestone, Lloyd W. Ruddock, Brian S. Cox, and Mick F. Tuite PMCID: PMC26647 Repetitive-DNA elements are similarly distributed on Caenorhabditis elegans autosomes Stefan A. Surzycki and William R. Belknap PMCID: PMC26648 Analysis of microsatellite mutations in the mitochondrial DNA of Saccharomyces cerevisiae Elaine Ayres Sia, Christine A. Butler, Margaret Dominska, Patricia Greenwell, Thomas D. Fox, and Thomas D. Petes PMCID: PMC26649 Circadian rhythms in Neurospora crassa: Lipid deficiencies restore robust rhythmicity to null frequency and white-collar mutants Patricia L. Lakin-Thomas and Stuart Brody PMCID: PMC26650 Knowledge-based analysis of microarray gene expression data by using support vector machines Michael P. S. Brown, William Noble Grundy, David Lin, Nello Cristianini, Charles Walsh Sugnet, Terrence S. Furey, Manuel Ares, Jr., and David Haussler PMCID: PMC26651 A human model for multigenic inheritance: Phenotypic expression in Hirschsprung disease requires both the RET gene and a new 9q31 locus Stacey Bolk, Anna Pelet, Robert M. W. Hofstra, Misha Angrist, Remi Salomon, David Croaker, Charles H. C. M. Buys, Stanislas Lyonnet, and Aravinda Chakravarti PMCID: PMC26652 Immunology Diversity, functionality, and stability of the T cell repertoire derived in vivo from a single human T cell precursor Philippe Bousso, Volker Wahn, Iyadh Douagi, Gerd Horneff, Christophe Pannetier, Françoise Le Deist, Fred Zepp, Tim Niehues, Philippe Kourilsky, Alain Fischer, and Geneviève de Saint Basile PMCID: PMC26653 A mouse CD8 T cell-mediated acute autoimmune diabetes independent of the perforin and Fas cytotoxic pathways: Possible role of membrane TNF Pedro Luis Herrera, David M. Harlan, and Pierre Vassalli PMCID: PMC26654 Induction of resistance to diabetes in non-obese diabetic mice by targeting CD44 with a specific monoclonal antibody Lola Weiss, Shimon Slavin, Shoshana Reich, Patrizia Cohen, Svetlana Shuster, Robert Stern, Ella Kaganovsky, Elimelech Okon, Ariel M. Rubinstein, and David Naor PMCID: PMC26655 Use of soluble peptide–DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis Brian L. Kotzin, Michael T. Falta, Frances Crawford, Edward F. Rosloniec, Jerry Bill, Philippa Marrack, and John Kappler PMCID: PMC26656 Prophylactic DNA vaccine for hepatitis C virus (HCV) infection: HCV-specific cytotoxic T lymphocyte induction and protection from HCV-recombinant vaccinia infection in an HLA-A2.1 transgenic mouse model Tatsumi Arichi, Takafumi Saito, Marian E. Major, Igor M. Belyakov, Mutsunori Shirai, Victor H. Engelhard, Stephen M. Feinstone, and Jay A. Berzofsky PMCID: PMC26657 Medical Sciences Chromosomal instability and cytoskeletal defects in oral cancer cells William S. Saunders, Michele Shuster, Xin Huang, Burhan Gharaibeh, Akon H. Enyenihi, Iver Petersen, and Susanne M. Gollin PMCID: PMC26658 The IgG Fc receptor, FcγRIIB, is a target for deregulation by chromosomal translocation in malignant lymphoma Mary B. Callanan, Patricia Le Baccon, Pascal Mossuz, Samuel Duley, Christian Bastard, Rifat Hamoudi, Martin J. Dyer, Gustav Klobeck, Ruth Rimokh, Jean Jacques Sotto, and Dominique Leroux PMCID: PMC26659 Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy Keita Kunisada, Shinji Negoro, Eiroh Tone, Masanobu Funamoto, Tomoaki Osugi, Shuichi Yamada, Masaru Okabe, Tadamitsu Kishimoto, and Keiko Yamauchi-Takihara PMCID: PMC26660 The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice Yoshihiro Yamada, Richard Pannell, Alan Forster, and Terence H. Rabbitts PMCID: PMC26661 Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: Relation to hypercortisolism and corticotropin-releasing hormone Ma-Li Wong, Mitchel A. Kling, Peter J. Munson, Samuel Listwak, Julio Licinio, Paolo Prolo, Brian Karp, Ian E. McCutcheon, Thomas D. Geracioti, Jr., Michael D. DeBellis, Kenner C. Rice, David S. Goldstein, Johannes D. Veldhuis, George P. Chrousos, Edward H. Oldfield, Samuel M. McCann, and Philip W. Gold PMCID: PMC26662 Potent antimalarial activity of clotrimazole in in vitro cultures of Plasmodium falciparum Teresa Tiffert, Hagai Ginsburg, Miriam Krugliak, Barry C. Elford, and Virgilio L. Lew PMCID: PMC26663 Estrogen receptors α and β in the rodent mammary gland Shigehira Saji, Elwood V. Jensen, Stefan Nilsson, Tove Rylander, Margaret Warner, and Jan-Åke Gustafsson PMCID: PMC26664 The long cytoplasmic tail of gp41 is required in a cell type-dependent manner for HIV-1 envelope glycoprotein incorporation into virions Tsutomu Murakami and Eric O. Freed PMCID: PMC26665 Generation of longer cDNA fragments from serial analysis of gene expression tags for gene identification Jian-Jun Chen, Janet D. Rowley, and San Ming Wang PMCID: PMC26666 Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene Tomoaki Goto, Toru Nishi, Takahiko Tamura, Sukhendu B. Dev, Hideo Takeshima, Masato Kochi, Kimio Yoshizato, Jun-ichi Kuratsu, Tsuneaki Sakata, Gunter A. Hofmann, and Yukitaka Ushio PMCID: PMC26667 A platelet–endothelium interaction mediated by lectin-like oxidized low-density lipoprotein receptor-1 Makoto Kakutani, Tomoh Masaki, and Tatsuya Sawamura PMCID: PMC26668 Infusion of α-galactosidase A reduces tissue globotriaosylceramide storage in patients with Fabry disease R. Schiffmann, G. J. Murray, D. Treco, P. Daniel, M. Sellos-Moura, M. Myers, J. M. Quirk, G. C. Zirzow, M. Borowski, K. Loveday, T. Anderson, F. Gillespie, K. L. Oliver, N. O. Jeffries, E. Doo, T. J. Liang, C. Kreps, K. Gunter, K. Frei, K. Crutchfield, R. F. Selden, and R. O. Brady PMCID: PMC26669 Percutaneous peptide immunization via corneum barrier-disrupted murine skin for experimental tumor immunoprophylaxis Naohiro Seo, Yoshiki Tokura, Takafumi Nishijima, Hideo Hashizume, Fukumi Furukawa, and Masahiro Takigawa PMCID: PMC26670 Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation Wen Yong Chen and Tim M. Townes PMCID: PMC26671 Luteinizing hormone induction of ovarian tumors: Oligogenic
differences between mouse strains dictates tumor disposition Ruth A. Keri, Kristen L. Lozada, Fadi W. Abdul-Karim, Joseph H. Nadeau, and John H. Nilson PMCID: PMC26672 Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: Implications for bone marrow metastasis Deeppreet Singh, Deval D. Joshi, Meera Hameed, Jing Qian, Pedro Gascón, Paul B. Maloof, Anne Mosenthal, and Pranela Rameshwar PMCID: PMC26673 The Nef protein of HIV-1 associates with rafts and primes T cells for activation Jen-Kuei Wang, Etsuko Kiyokawa, Eric Verdin, and Didier Trono PMCID: PMC26674 Melan-A/MART-151–73 represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4+ T cells Hassane M. Zarour, John M. Kirkwood, Lisa Salvucci Kierstead, Wolfgang Herr, Vladimir Brusic, Craig L. Slingluff, Jr., John Sidney, Alessandro Sette, and Walter J. Storkus PMCID: PMC26675 The role of phosphoglycans in Leishmania–sand fly interactions David L. Sacks, Govind Modi, Edgar Rowton, Gerald Späth, Linda Epstein, Salvatore J. Turco, and Stephen M. Beverley PMCID: PMC26676 Microbiology Identification of bdm-1, a gene involved in G protein β-subunit function and α-subunit accumulation Shin Kasahara, Ping Wang, and Donald L. Nuss PMCID: PMC26677 Treatment of Mycobacterium tuberculosis with antisense oligonucleotides to glutamine synthetase mRNA inhibits glutamine synthetase activity, formation of the poly-l-glutamate/glutamine cell wall structure, and bacterial replication Günter Harth, Paul C. Zamecnik, Jin-Yan Tang, David Tabatadze, and Marcus A. Horwitz PMCID: PMC26678 A host-specific function is required for ligation of a wide variety of ribozyme-processed RNAs Carl E. Reid and David W. Lazinski PMCID: PMC26679 Epstein–Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoter Lian Wang, Steven R. Grossman, and Elliott Kieff PMCID: PMC26680 Neurobiology Requirement for nitric oxide activation of p21ras/extracellular regulated kinase in neuronal ischemic preconditioning Mirella Gonzalez-Zulueta, Alicia B. Feldman, Laura J. Klesse, Robert G. Kalb, James F. Dillman, Luis F. Parada, Ted M. Dawson, and Valina L. Dawson PMCID: PMC26681 Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system Markus Glatzel, Eckhard Flechsig, Beatriz Navarro, Michael A. Klein, Jean C. Paterna, Hansruedi Büeler, and Adriano Aguzzi PMCID: PMC26682 Reactive oxygen species and nitric oxide mediate plasticity of neuronal calcium signaling Olena Yermolaieva, Nathan Brot, Herbert Weissbach, Stefan H. Heinemann, and Toshinori Hoshi PMCID: PMC26683 Effects of salicylates and aminoglycosides on spontaneous otoacoustic emissions in the Tokay gecko Charles E. Stewart and A. James Hudspeth PMCID: PMC26684 A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum Heidi A. Tissenbaum, John Hawdon, Melissa Perregaux, Peter Hotez, Leonard Guarente, and Gary Ruvkun PMCID: PMC26685 Epistatic and independent functions of Caspase-3 and Bcl-XL in developmental programmed cell death K. A. Roth, C.-Y. Kuan, T. F. Haydar, C. D'Sa-Eipper, K. S. Shindler, T. S. Zheng, K. Kuida, R. A. Flavell, and P. Rakic PMCID: PMC26686 Pharmacology Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase J. M. Hetman, S. H. Soderling, N. A. Glavas, and J. A. Beavo PMCID: PMC26687 Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein Linda L. Pearce, Robin E. Gandley, Weiping Han, Karla Wasserloos, Molly Stitt, Anthony J. Kanai, Margaret K. McLaughlin, Bruce R. Pitt, and Edwin S. Levitan PMCID: PMC26688 Physiology Corticotropin-releasing hormone causes antidiuresis and antinatriuresis by stimulating vasopressin and inhibiting atrial natriuretic peptide release in male rats J. Gutkowska, M. Jankowski, S. Mukaddam-Daher, and S. M. McCann PMCID: PMC26689 Plant Biology Cloning of the Arabidopsis RTM1
gene, which controls restriction of long-distance movement of
tobacco etch virus Stephen T. Chisholm, Sunita K. Mahajan, Steven A. Whitham, Miki L. Yamamoto, and James C. Carrington PMCID: PMC26690 Nucleotide binding and autophosphorylation of the clock protein KaiC as a circadian timing process of cyanobacteria Taeko Nishiwaki, Hideo Iwasaki, Masahiro Ishiura, and Takao Kondo PMCID: PMC26691 Psychology From the Cover:
Explaining the moon illusion Lloyd Kaufman and James H. Kaufman PMCID: PMC26692 From the Cover:
Prefrontal cortex and episodic memory retrieval mode Martin Lepage, Omar Ghaffar, Lars Nyberg, and Endel Tulving PMCID: PMC26693 Contribution of S opponent cells to color appearance Russell L. De Valois, Karen K. De Valois, and Luke E. Mahon PMCID: PMC26694 Social Sciences Anthropology Statistical methods for characterizing similarities and differences between semantic structures A. Kimball Romney, Carmella C. Moore, William H. Batchelder, and Ti-Lien Hsia PMCID: PMC26695 |
