| | This journal provides immediate access to some articles. Colloquium Papers Genetics and the origin of species: An  introduction Francisco J. Ayala and Walter M. Fitch PMCID: PMC33678 Origin of Genes Walter Gilbert, Sandro J. de Souza, and Manyuan Long PMCID: PMC33679 Transposable elements as sources of variation in animals
and plants Margaret G. Kidwell and Damon Lisch PMCID: PMC33680 Long term trends in the evolution of H(3) HA1 human influenza
type A Walter M. Fitch, Robin M. Bush, Catherine A. Bender, and Nancy J. Cox PMCID: PMC33681 Genes, peoples, and languages L. Luca Cavalli-Sforza PMCID: PMC33682 DNA variation at the Sod locus of
Drosophila melanogaster: An unfolding story of
natural selection Richard R. Hudson, Alberto G. Sáez, and Francisco J. Ayala PMCID: PMC33684 Neutral behavior of shared polymorphism Andrew G. Clark PMCID: PMC33687 Divergent and conserved features in the spatial expression of the
Drosophila pseudoobscura
esterase-5B gene and the
esterase-6 gene of DrosophilamelanogasterNatalia A. Tamarina, Michael Z. Ludwig, and Rollin C. Richmond PMCID: PMC33691 A demographic approach to selection Wyatt W. Anderson and Takao K. Watanabe PMCID: PMC33694 Phylogenetics and the origin of species John C. Avise and Kurt Wollenberg PMCID: PMC33696 Assortative fertilization in DrosophilaTherese Ann Markow PMCID: PMC33700 Incipient species formation in salamanders of the
Ensatinacomplex David B. Wake PMCID: PMC33701 Genetics and the origin of bird species Peter R. Grant and B. Rosemary Grant PMCID: PMC33702 Vagaries of the molecular clock Francisco J. Ayala PMCID: PMC33703 Evolution of codon usage bias in DrosophilaJeffrey R. Powell and Etsuko N. Moriyama PMCID: PMC33704 The evolution of plant nuclear genes Michael T. Clegg, Michael P. Cummings, and Mary L. Durbin PMCID: PMC33705 Evolution by the birth-and-death process in multigene families of
the vertebrate immune system Masatoshi Nei, Xun Gu, and Tatyana Sitnikova PMCID: PMC33709 Perspective The radioactivity of atmospheric krypton in 1949–1950 Anthony Turkevich, Lester Winsberg, Howard Flotow, and Richard M. Adams PMCID: PMC33711 Review Immunity to retroviral infection: The Friend virus model Kim J. Hasenkrug and Bruce Chesebro PMCID: PMC33712 Physical Sciences Applied Mathematics Structure of the zero-pressure-gradient turbulent boundary layer G. I. Barenblatt, A. J. Chorin, O. H. Hald, and V. M. Prostokishin PMCID: PMC21511 Biological Sciences Biochemistry Association of the mammalian helicase MAH with the pre-mRNA splicing complex Gyongyi M. Molnar, Anne Crozat, Stine-Kathrein Kraeft, Qing Ping Dou, Lan Bo Chen, and Arthur B. Pardee PMCID: PMC21514 Helical repeat of DNA in the region of homologous pairing Konstantin Kiianitsa and Andrzej Stasiak PMCID: PMC21515 Allosteric intermediates indicate R2 is the liganded hemoglobin end state Maria A. Schumacher, Ekaterina E. Zheleznova, Kitty S. Poundstone, Ronald Kluger, Richard T. Jones, and Richard G. Brennan PMCID: PMC21516 Total chemical synthesis of enzymatically active human type II secretory phospholipase A 2Tilman M. Hackeng, Carine M. Mounier, Cassian Bon, Philip E. Dawson, John H. Griffin, and Stephen B. H. Kent PMCID: PMC21517 A DnaB intein in Rhodothermus marinus: Indication of recent intein homing across remotely related organisms Xiang-Qin Liu and Zhuma Hu PMCID: PMC21518 X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release Benoît Gigant, Jean-Baptiste Charbonnier, Zelig Eshhar, Bernard S. Green, and Marcel Knossow PMCID: PMC21519 Direct involvement of the ubiquitin-conjugating enzyme Ubc9/Hus5 in the degradation of IκBα Kei Tashiro, Matthew P. Pando, Yumi Kanegae, Penny M. Wamsley, Satoshi Inoue, and Inder M. Verma PMCID: PMC21520 The p53 tumor suppressor targets a novel regulator of G protein signaling Leonard Buckbinder, Susana Velasco-Miguel, Yan Chen, Ningzhi Xu, Randy Talbott, Larry Gelbert, Jizong Gao, Bernd R. Seizinger, J. Silvio Gutkind, and Nikolai Kley PMCID: PMC21521 Human and Saccharomyces cerevisiae dolichol phosphate mannose synthases represent two classes of the enzyme, but both function in SchizosaccharomycespombePaul A. Colussi, Christopher H. Taron, Jamey C. Mack, and Peter Orlean PMCID: PMC21522 Steroid receptor induction of gene transcription: A two-step model Guido Jenster, Thomas E. Spencer, Mark M. Burcin, Sophia Y. Tsai, Ming-Jer Tsai, and Bert W. O’Malley PMCID: PMC21523 α-Tocopheryl hydroquinone is an efficient multifunctional inhibitor of radical-initiated oxidation of low density lipoprotein lipids Jiří Neužil, Paul K. Witting, and Roland Stocker PMCID: PMC21524 The herpes simplex virus 1 protein kinase U S3 is required for protection from apoptosis induced by the virus Rosario Leopardi, Charles Van Sant, and Bernard Roizman PMCID: PMC21525 The major yeast poly(A)-binding protein is associated with cleavage factor IA and functions in premessenger RNA 3′-end formation Lionel Minvielle-Sebastia, Pascal J. Preker, Thomas Wiederkehr, Yvan Strahm, and Walter Keller PMCID: PMC21526 Leishmania tarentolae contains distinct cytosolic and mitochondrial glutaminyl–tRNA synthetase activities Christoph E. Nabholz, Remy Hauser, and André Schneider PMCID: PMC21527 Activation of the orphan receptor RIP14 by retinoids Ann Marie Zavacki, Jürgen M. Lehmann, Wongi Seol, Timothy M. Willson, Steven A. Kliewer, and David D. Moore PMCID: PMC21528 The Xenopus proglucagon gene encodes novel GLP-1-like peptides with insulinotropic properties David M. Irwin, Malathy Satkunarajah, Yi Wen, Patricia L. Brubaker, Raymond A. Pederson, and Michael B. Wheeler PMCID: PMC21529 Targeted inactivation of α i2 or α i3 disrupts activation of the cardiac muscarinic K + channel, I K+Ach, in intact cells Margaret O. Sowell, Chianping Ye, Dennis A. Ricupero, Sherry Hansen, Stephen J. Quinn, Peter M. Vassilev, and Richard M. Mortensen PMCID: PMC21530 Biophysics Detection of single-molecule interactions using correlated thermal diffusion A. D. Mehta, J. T. Finer, and J. A. Spudich PMCID: PMC21531 Nonexponential kinetics of a single tRNA Phe molecule under physiological conditions Yiwei Jia, Alexander Sytnik, Liangquan Li, Serguei Vladimirov, Barry S. Cooperman, and Robin M. Hochstrasser PMCID: PMC21532 Microsecond atomic force sensing of protein conformational dynamics: Implications for the primary light-induced events in bacteriorhodopsin Itay Rousso, Edward Khachatryan, Yahaloma Gat, Igor Brodsky, Michael Ottolenghi, Mordechai Sheves, and Aaron Lewis PMCID: PMC21533 Kinetic theory of fibrillogenesis of amyloid β-protein Aleksey Lomakin, David B. Teplow, Daniel A. Kirschner, and George B. Benedek PMCID: PMC21534 Cell Biology Phosphorylation and subunit organization of axonal neurofilaments determined by scanning transmission electron microscopy R. D. Leapman, P. E. Gallant, T. S. Reese, and S. B. Andrews PMCID: PMC21512 Inducible gene expression and protein translocation using nontoxic ligands identified by a mammalian three-hybrid screen Stephen D. Liberles, Steven T. Diver, David J. Austin, and Stuart L. Schreiber PMCID: PMC21513 Nuclear localization of basonuclin in human keratinocytes and the role of phosphorylation Shiro Iuchi and Howard Green PMCID: PMC21535 Tumor induction by a transformation-defective polyoma virus mutant blocked in signaling through Shc Roderick Bronson, Clyde Dawe, John Carroll, and Thomas Benjamin PMCID: PMC21536 Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion Hirokazu Nakahara, Linda Howard, Erik W. Thompson, Hiroshi Sato, Motoharu Seiki, Yunyun Yeh, and Wen-Tien Chen PMCID: PMC21537 The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex Xiangwei He, Thomas E. Patterson, and Shelley Sazer PMCID: PMC21538 Roles of phospholipase C β2 in chemoattractant-elicited responses Huiping Jiang, Yanan Kuang, Yanping Wu, Wei Xie, Melvin I. Simon, and Dianqing Wu PMCID: PMC21539 Developmental Biology An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice Michael A. McDevitt, Yuko Fujiwara, Ramesh A. Shivdasani, and Stuart H. Orkin PMCID: PMC21540 An important developmental role for oligosaccharides during early embryogenesis of cyprinid fish Jeroen Bakkers, Carlos E. Semino, Henri Stroband, Jan W. Kijne, Phillips W. Robbins, and Herman P. Spaink PMCID: PMC21541 Evolution Phylogeny of the genus Pistacia as determined from analysis of the chloroplast genome Dan E. Parfitt and Maria L. Badenes PMCID: PMC21542 An upper dentition of Aframonius dieides (Primates) from the Fayum, Egyptian Eocene Elwyn L. Simons and Ellen R. Miller PMCID: PMC21543 Functional and nonfunctional mutations distinguished by random recombination of homologous genes Huimin Zhao and Frances H. Arnold PMCID: PMC21544 Cleavage patterns and the topology of the metazoan tree of life James W. Valentine PMCID: PMC21545 Molecular evidence that echiurans and pogonophorans are derived annelids Damhnait McHugh PMCID: PMC21546 Genetics Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of SaccharomycescerevisiaeJ. Pablo Radicella, Claudine Dherin, Chantal Desmaze, Maurice S. Fox, and Serge Boiteux PMCID: PMC21547 Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase Teresa Roldán-Arjona, Ying-Fei Wei, Kenneth C. Carter, Arne Klungland, Catherine Anselmino, Rui-Ping Wang, Meena Augustus, and Tomas Lindahl PMCID: PMC21548 Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype Ning Zhang, Philip Chen, Kum Kum Khanna, Shaun Scott, Magtouf Gatei, Sergei Kozlov, Dianne Watters, Kevin Spring, Tim Yen, and Martin F. Lavin PMCID: PMC21549 Transitions in the coupling of transcription and nucleotide excision repair within RNA polymerase II-transcribed genes of SaccharomycescerevisiaeMarcel Tijsterman, Richard A. Verhage, Pieter van de Putte, Judith G. Tasseron-de Jong, and Jaap Brouwer PMCID: PMC21550 The one ancestor per generation rule and three other rules of mitochondrial inheritance Susumu Ohno PMCID: PMC21551 Synergistic and promoter-selective activation of transcription by recruitment of transcription factors TFIID and TFIIB Eduardo Gonzalez-Couto, Natacha Klages, and Michel Strubin PMCID: PMC21552 Retention of replication fidelity by a DNA polymerase functioning in a distantly related environment Holly Kloos Dressman, Chien-Chia Wang, Jim D. Karam, and John W. Drake PMCID: PMC21553 Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma Richard J. Davis and Frederic G. Barr PMCID: PMC21554 High genetic instability of heterochromatin after transposition of the LINE-like I factor in DrosophilamelanogasterPatrizio Dimitri, Bruno Arcà, Libera Berghella, and Elisabetta Mei PMCID: PMC21555 The hotspot conversion paradox and the evolution of meiotic recombination Alan Boulton, Richard S. Myers, and Rosemary J. Redfield PMCID: PMC21556 Immunology Direct delivery of exogenous MHC class I molecule-binding oligopeptides to the endoplasmic reticulum of viable cells Patricia M. Day, Jonathan W. Yewdell, Angel Porgador, Ronald N. Germain, and Jack R. Bennink PMCID: PMC21557 A single peripheral CD8 + T cell can give rise to progeny expressing type 1 and/or type 2 cytokine genes and can retain its multipotentiality through many cell divisions Anne Kelso and Penny Groves PMCID: PMC21558 Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination Yansong Gu, Shengfang Jin, Yijie Gao, David T. Weaver, and Frederick W. Alt PMCID: PMC21559 Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(α1*0101,β1*0401) transgenic mice Salil D. Patel, Andrew P. Cope, Mauro Congia, Teddy T. Chen, Eugene Kim, Lars Fugger, Diane Wherrett, and Grete Sonderstrup-McDevitt PMCID: PMC21560 Natural killer cell acceptance of H-2 mismatch bone marrow grafts in transgenic mice expressing HLA-Cw3 specific killer cell inhibitory receptor (CD158b) Anna Cambiaggi, Christophe Verthuy, Philippe Naquet, François Romagné, Pierre Ferrier, Roberto Biassoni, Alessandro Moretta, Lorenzo Moretta, and Eric Vivier PMCID: PMC21561 Characterization of tumor necrosis factor-deficient mice Michael W. Marino, Ashley Dunn, Dianne Grail, Melissa Inglese, Yuji Noguchi, Elizabeth Richards, Achim Jungbluth, Hisashi Wada, Malcolm Moore, Barbara Williamson, Sunanda Basu, and Lloyd J. Old PMCID: PMC21562 Medical Sciences Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer Eugene D. Kwon, Arthur A. Hurwitz, Barbara A. Foster, Christopher Madias, Andrew L. Feldhaus, Norman M. Greenberg, Maurice B. Burg, and James P. Allison PMCID: PMC21563 Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth P. H. Maxwell, G. U. Dachs, J. M. Gleadle, L. G. Nicholls, A. L. Harris, I. J. Stratford, O. Hankinson, C. W. Pugh, and P. J. Ratcliffe PMCID: PMC21564 Modified cytokeratins expressed on the surface of carcinoma cells undergo endocytosis upon binding of human monoclonal antibody and its recombinant Fab fragment Henrik J. Ditzel, Ursula Garrigues, Claus B. Andersen, Morten K. Larsen, H. Jacques Garrigues, Arne Svejgaard, Ingegerd Hellström, Karl Erik Hellström, and Jens C. Jensenius PMCID: PMC21565 Tat protein induces self-perpetuating permissivity for productive HIV-1 infection Chiang J. Li, Yutaka Ueda, Bin Shi, Laura Borodyansky, Lili Huang, You-Zhi Li, and Arthur B. Pardee PMCID: PMC21566 Transgenic Gαq overexpression induces cardiac contractile failure in mice Drew D. D’Angelo, Yoshihito Sakata, John N. Lorenz, Gregory P. Boivin, Richard A. Walsh, Stephen B. Liggett, and Gerald W. Dorn, II PMCID: PMC21567 Macrophages lacking scavenger receptor A show a decrease in binding and uptake of acetylated low-density lipoprotein and of apoptotic thymocytes, but not of oxidatively damaged red blood cells Valeska Terpstra, Nonna Kondratenko, and Daniel Steinberg PMCID: PMC21568 Altered expression of the WT1 Wilms tumor suppressor gene in human breast cancer Gary B. Silberstein, Katharine Van Horn, Phyllis Strickland, Charles T. Roberts, Jr., and Charles W. Daniel PMCID: PMC21569 Mouse model of G M2 activator deficiency manifests cerebellar pathology and motor impairment Yujing Liu, Alexander Hoffmann, Alexander Grinberg, Heiner Westphal, Michael P. McDonald, Katherine M. Miller, Jacqueline N. Crawley, Konrad Sandhoff, Kinuko Suzuki, and Richard L. Proia PMCID: PMC21570 Thymineless death in colon carcinoma cells is mediated via Fas signaling Janet A. Houghton, Franklin G. Harwood, and David M. Tillman PMCID: PMC21571 The antisense bcl-2– IgH transcript is an optimal target for synthetic oligonucleotides Susanna Morelli, Domenico Delia, Sergio Capaccioli, Alessandro Quattrone, Nicola Schiavone, Anna Bevilacqua, Silvia Tomasini, and Angelo Nicolin PMCID: PMC21572 Growth arrest of Epstein–Barr virus immortalized B lymphocytes by adenovirus-delivered ribozymes Shuang Huang, Dwayne Stupack, Patricia Mathias, Yibing Wang, and Glen Nemerow PMCID: PMC21573 Microbiology The hepatitis B virus X gene induces p53-mediated programmed cell death Paolo Chirillo, Sabrina Pagano, Gioacchino Natoli, Pier Lorenzo Puri, Vito Lelio Burgio, Clara Balsano, and Massimo Levrero PMCID: PMC21574 Gene expression from plasmids containing the araBAD promoter at subsaturating inducer concentrations represents mixed populations Deborah A. Siegele and James C. Hu PMCID: PMC21575 Neurobiology Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Iβ gene expression followed by late-onset neuromotor deterioration Christian Andres, Rachel Beeri, Alon Friedman, Efrat Lev-Lehman, Sivan Henis, Rina Timberg, Moshe Shani, and Hermona Soreq PMCID: PMC21576 Intracisternal basic fibroblast growth factor enhances functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction Takakazu Kawamata, W. Dalton Dietrich, Timothy Schallert, Jeffrey E. Gotts, Robert R. Cocke, Larry I. Benowitz, and Seth P. Finklestein PMCID: PMC21577 Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain Luciano Conti, Claudio De Fraja, Massimo Gulisano, Enrica Migliaccio, Stefano Govoni, and Elena Cattaneo PMCID: PMC21578 Brain-derived neurotrophic factor rapidly enhances phosphorylation of the postsynaptic N-methyl- d-aspartate receptor subunit 1 Piin-Chau Suen, Kuo Wu, Eric S. Levine, Howard T. J. Mount, Jia-Ling Xu, Siang-Yo Lin, and Ira B. Black PMCID: PMC21579 Disruption of hippocampal development in vivo by CR-50 mAb against Reelin Kazunori Nakajima, Katsuhiko Mikoshiba, Takaki Miyata, Chikako Kudo, and Masaharu Ogawa PMCID: PMC21580 Fixation of allosteric states of the nicotinic acetylcholine receptor by chemical cross-linking Anke Watty, Christoph Methfessel, and Ferdinand Hucho PMCID: PMC21581 Interaction between amyloid precursor protein and presenilins in mammalian cells: Implications for the pathogenesis of Alzheimer disease Weiming Xia, Jimin Zhang, Ruth Perez, Edward H. Koo, and Dennis J. Selkoe PMCID: PMC21582 Opioid receptors from a lower vertebrate ( Catostomus commersoni): Sequence, pharmacology, coupling to a G-protein-gated inward-rectifying potassium channel (GIRK1), and evolution Mark G. Darlison, Florian R. Greten, Robert J. Harvey, Hans-Jürgen Kreienkamp, Thorsten Stühmer, Henk Zwiers, Karl Lederis, and Dietmar Richter PMCID: PMC21583 Pharmacology Functionally differentiating two neuronal nitric oxide synthase isoforms through antisense mapping: Evidence for opposing NO actions on morphine analgesia and tolerance Yuri A. Kolesnikov, Ying-Xian Pan, Anna-Marie Babey, Subash Jain, Roger Wilson, and Gavril W. Pasternak PMCID: PMC21584 Nitrergic control of peripheral sympathetic responses in the human corpus cavernosum: A comparison with other species Selim Cellek and Salvador Moncada PMCID: PMC21585 Quantitative trait loci controlling halothane sensitivity in CaenorhabditiselegansBruno van Swinderen, David R. Shook, Robert H. Ebert, Vera A. Cherkasova, Thomas E. Johnson, Robert J. Shmookler Reis, and C. Michael Crowder PMCID: PMC21586 Physiology Specific requirement of putrescine for the mitogenic action of juvenile hormone on adult insect neuroblasts Myriam Cayre, Colette Strambi, Pierre Charpin, Roger Augier, and Alain Strambi PMCID: PMC21587 Plant Biology AtMRP1 gene of Arabidopsis encodes a glutathione S-conjugate pump: Isolation and functional definition of a plant ATP-binding cassette transporter gene Yu-Ping Lu, Ze-Sheng Li, and Philip A. Rea PMCID: PMC21588 Cloning of a polycistronic cDNA from tomato encoding γ-glutamyl kinase and γ-glutamyl phosphate reductase Mario García-Ríos, Tomomichi Fujita, P. Christopher LaRosa, Robert D. Locy, Jean M. Clithero, Ray A. Bressan, and Laszlo N. Csonka PMCID: PMC21589 Inheritance, gene expression, and lignin characterization in a mutant pine deficient in cinnamyl alcohol dehydrogenase John J. MacKay, David M. O’Malley, Timothy Presnell, Fitzgerald L. Booker, Malcolm M. Campbell, Ross W. Whetten, and Ronald R. Sederoff PMCID: PMC21590 Nontarget DNA sequences reduce the transgene length necessary for RNA-mediated tospovirus resistance in transgenic plants Sheng-Zhi Pang, Fuh-Jyh Jan, and Dennis Gonsalves PMCID: PMC21591 Social Sciences Psychology Integration of local pattern elements into a global shape in human vision Jukka Saarinen, Dennis M. Levi, and Bridgitte Shen PMCID: PMC21592 Corrections Proc Natl Acad Sci U S A. 1997 July 22; 94(15): 8272. PMCID: PMC56138 Corrects: Ivan Huc, et al. Virtual combinatorial libraries: Dynamic generation of molecular and supramolecular diversitybyself-assembly. Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2106–2110. Proc Natl Acad Sci U S A. 1997 July 22; 94(15): 8272. PMCID: PMC56139 Corrects: Edward Giovannucci, et al. The CAG repeat within the androgen receptor gene and its relationship to prostatecancer. Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3320–3323. |
